Case Report: Acute Fatty Liver Of Pregnancy In A 30-year Old Nigerian Primigravida

Acute fatty liver of pregnancy is an uncommon, potentially fatal disorder that usually occurs in the third trimester of pregnancy or in the early post partum. We present here a 30-year-old Nigerian primigravida with acute fatty liver of pregnancy. She was successfully managed and discharged. Keywords: Acute fatty liver of pregnancy. Nigerian Journal of Clinical Practice Vol. 11 (4) 2008: pp. 389-39

Identification of subdominant lactic acid bacteria in dawadawa (a soup condiment) and their evolution during laboratory-scale fermentation of Parkia biglobosa (African locust beans)

The successive colonization of fermenting African locust beans (Parkia biglobosa) by lactic acid bacteria (LAB) was investigated for seven days. The LAB isolated were Pediococcus pentosaceus, Lactobacillus raffinolactus, Leuconostoc mesenteroides, Leuconostoc sp, Pediococcus halophilus,Pediococcus sp, Lactobacillus sp, Lactobacillus plantarum, Lactobacillus acidophilus and Lactobacillus brevis. The first dominant species were P. pentosaceus, which was more in abundance, L. raffinolactus, L. mesenteroides and another Leuconostoc sp. At the end of fermentation, a stable community comprising of P. halophilus, P. pentasaceus and L. brevis was formed. The dominant genera in this study were Lactobacillus and Pediococcus. The proximate analysis of the fermenting andfermented mash showed an increase in moisture content from 55.1 to 65.2%, pH from 6.25 to a stable alkaline value of 8.4. The reducing sugar however, decreased from 0.96 to 0.58 mg. The amino acid content increased from an initial value of 8.13 to 35.55 mg for the laboratory-scale product, whereas the value of the control was 13.4 mg. The total viable count increased from an initial value of log102.6 to log105.8 and then fell to a final value of log104.1. The enterococci count increased initially but eventually fell to zero. The total yeast count increased initially from log105.3 to log106.6 and thereafter fell to zero. The market sample had a value of log101.5. No coliforms were found in the course of fermentation as well as in the final product of the laboratory-scale experiment and the market sample

The evaluation of intranasal Lactobacillus fermentum and Mannheimia haemolytica bacterine in the control of Mannheimia haemolytica infection in grasscutter (Thryonomys swinderianus temminck, 1827)

This study evaluates the effect of recombinant Mannheimia hemolytica bacterine and Lactobacillus fermentum intranasal administration on experimental pneumonic Mannheimiosis in grasscutters (Thryonomys swinderianus Temminck, 1827). This investigation involved apparently healthy adult grasscutters that were divided into groups A, B, C, D, E, F, G and H of three (3) grasscutters each with group H serving as the control. Group A (vaccinated twice with bacterin and infected), group B (vaccinated once with bacterin and infected), group C, E (vaccinated, inoculated with Lactobacillus fermentum and infected), group D (inoculated with Lactobacillus fermentum alone), group F (infected), group G (grasscutters infected and later inoculated with Lactobacillus fermentum) and lastly group H (control). The mortality pattern, pathology of the respiratory tract and nasal bacterial load were assessed using standard methods. The result showed that intranasal application of Lactobacillus fermentum and or recombinant Mannheimia haemolytica bacterine reduces the nasal bacterial load, pathology and mortality pattern associated with experimental Mannheimia haemolytica infection in the grasscutter hence they could be useful in the control of respiratory disorders in grasscutters.Keywords: grasscutter, bacterin, experimental, respiratory, infectio