681 research outputs found
Organizing International Technological Collaboration in Subcontractor Relationships An Investigation of the Knowledge-Stickyness Problem
Technological knowledge is often claimed to be context-bound and sticking to local surroundings. This paper investigates how technological knowledge can be exchanged in international subcontractor relationships, using relationship-oriented organizational practices. Five hypotheses concerning such practices are tested. It is shown that the use of relationshiporiented practices varies with exports and the active development of subcontractors in product and process development activities. Moreover, international development-oriented subcontractors are more likely to use interpersonal exchange, electronic data interchange and formalized contracts than other types of subcontractors. Research implications as well as managerial implications are derived.Subcontracting, knowledge, international division og labour
Efficient Forward Simulation of Fisher-Wright Populations with Stochastic Population Size and Neutral Single Step Mutations in Haplotypes
In both population genetics and forensic genetics it is important to know how
haplotypes are distributed in a population. Simulation of population dynamics
helps facilitating research on the distribution of haplotypes. In forensic
genetics, the haplotypes can for example consist of lineage markers such as
short tandem repeat loci on the Y chromosome (Y-STR). A dominating model for
describing population dynamics is the simple, yet powerful, Fisher-Wright
model. We describe an efficient algorithm for exact forward simulation of exact
Fisher-Wright populations (and not approximative such as the coalescent model).
The efficiency comes from convenient data structures by changing the
traditional view from individuals to haplotypes. The algorithm is implemented
in the open-source R package 'fwsim' and is able to simulate very large
populations. We focus on a haploid model and assume stochastic population size
with flexible growth specification, no selection, a neutral single step
mutation process, and self-reproducing individuals. These assumptions make the
algorithm ideal for studying lineage markers such as Y-STR.Comment: 17 pages, 6 figure
A gentle introduction to the discrete Laplace method for estimating Y-STR haplotype frequencies
Y-STR data simulated under a Fisher-Wright model of evolution with a
single-step mutation model turns out to be well predicted by a method using
discrete Laplace distributions.Comment: 18 pages, 5 figure
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