Application of Aboodh transforms to the solution of nth-order ordinary differential equations

The study applied the Aboodh transform as a convenient and effective tool to provide exact solution to nth-order ordinary differential equation with constant coefficient based on the simplicity of the Aboodh transform and its fundamental properties. The Laplace transform is used to validate the exact solution provided by the Aboodh transform method

Thermodynamic analysis of a variable viscosity reactive hydromagnetic couette flow within parallel plates

This investigation is to consider the impact of a temperature-dependent variable viscosity of a reactive hydromagnetic Couette fluid flowing within parallel plates. The variable property of the fluid viscosity is thought to be an exponential relation of temperature under the impact of magnetic strength. The differential equations controlling the smooth movement of fluid and energy transfer are modeled and solved by using the series solution of modified Adomian decomposition technique (mADM). The outcomes are shown in tables and graphs for different estimations of thermophysical properties present in the flow regime together with the rate of entropy generation and irreversibility distribution outcome. Keywords: Reactive fluids, Couette Flow, variable viscosity, hydromagnetic and modified Adomian decomposition method (mADM)

Mechanism of kinin release during experimental acute pancreatitis in rats: evidence for pro- as well as anti-inflammatory roles of oedema formation

1. Kinin B(2) receptor antagonists or tissue kallikrein (t-KK) inhibitors prevent oedema formation and associated sequelae in caerulein-induced pancreatitis in the rat. We have now further investigated the mechanism of kinin generation in the pancreas. 2. Kinins were elevated in the pancreatic tissue already before oedema formation became manifest. Peak values (421±59 pmol g(−1) dry wt) were reached at 45 min and remained elevated for at least 2 h; a second increase was observed at 24 h. Pretreatment with the B(2) receptor antagonist icatibant abolished kinin formation, while post-treatment was ineffective. 3. Total kininogen levels were very low in the pancreas of controls, but increased 75-fold during acute pancreatitis. This increase was absent in rats that were pretreated with icatibant. 4. During pancreatitis, t-KK-like and plasma kallikrein (p-KK)-like activity in the pancreas, as well as trypsinogen activation peptide (TAP) increased significantly. Icatibant pretreatment further augmented t-KK about 100-fold, while p-KK was significantly attenuated; TAP levels remained unaffected. 5. Endogenous protease inhibitors (α(1)-antitrypsin, α(2)-macroglobulin) were low in normal tissues, but increased 45- and four-fold, respectively, during pancreatitis. This increase was abolished when oedema formation was prevented by icatibant. 6. In summary, oedema formation is initiated by t-KK; the ensuing plasma protein extravasation supplies further kininogen and active p-KK to the tissue. Concomitantly, endogenous protease inhibitors in the oedema fluid inhibit up to 99% of active t-KK. Our data thus suggest a complex interaction between kinin action and kinin generation involving positive and negative feedback actions of the inflammatory oedema