Is it really possible to grow isotropic on-lattice diffusion-limited aggregates?

In a recent paper (Bogoyavlenskiy V A 2002 \JPA \textbf{35} 2533), an algorithm aiming to generate isotropic clusters of the on-lattice diffusion-limited aggregation (DLA) model was proposed. The procedure consists of aggregation probabilities proportional to the squared number of occupied sites ($k^2$). In the present work, we analyzed this algorithm using the noise reduced version of the DLA model and large scale simulations. In the noiseless limit, instead of isotropic patterns, a $45^\circ$ ($30^\circ$) rotation in the anisotropy directions of the clusters grown on square (triangular) lattices was observed. A generalized algorithm, in which the aggregation probability is proportional to $k^\nu$, was proposed. The exponent $\nu$ has a nonuniversal critical value $\nu_c$, for which the patterns generated in the noiseless limit exhibit the original (axial) anisotropy for $\nu<\nu_c$ and the rotated one (diagonal) for $\nu>\nu_c$. The values $\nu_c = 1.395\pm0.005$ and $\nu_c = 0.82\pm 0.01$ were found for square and triangular lattices, respectively. Moreover, large scale simulations show that there are a nontrivial relation between noise reduction and anisotropy direction. The case $\nu=2$ (\bogo's rule) is an example where the patterns exhibit the axial anisotropy for small and the diagonal one for large noise reduction.Comment: 12 pages, 8 figure

Role of cytokines and nitric oxide in the induction of tuberculostatic macrophage functions.

The aim of this study was to determine phenotypic differences when BCG invades macrophages. Bacilli prepared from the same BCG primary seed, but produced in different culture media, were analysed with respect to the ability to stimulate macrophages and the susceptibility to treatment with cytokines and nitric oxide (NO). Tumour necrosis factor (TNF) activity was assayed by measuring its cytotoxic activity on L-929 cells, interleukin-6 (IL-6) and interferon-gamma (IFN-gamma) were assayed by enzyme-linked immunosorbent assay (ELISA), whereas NO levels were detected by Griess colorimetric reactions in the culture supernatant of macrophages incubated with IFN-gamma, TNF or NO and subsequently exposed to either BCG-I or BCG-S. We found that BCG-I and BCG-S bacilli showed different ability to simulate peritoneal macrophages. Similar levels of IL-6 were detected in stimulated macrophages with lysate from two BCG samples. The highest levels of TNF and IFN-gamma were observed in macrophages treated with BCG-S and BCG-I, respectively. The highest levels of NO were observed in cultures stimulated for 48 h with BCG-S. We also found a different susceptibility of the bacilli to exogenous treatment with IFN-gamma and TNF which were capable of killing 60 and 70% of both bacilli, whereas NO was capable of killing about 98 and 47% of BCG-I and BCG-S, respectively. The amount of bacilli proportionally decreased with IFN-gamma and TNF, suggesting a cytokine-related cytotoxic effect. Moreover, NO also decreased the viable number of bacilli. Interestingly, NO levels of peritoneal macrophages were significantly increased after cytokine treatment. This indicates that the treatment of macrophages with cytokines markedly reduced bacilli number and presented effects on NO production. The results obtained here emphasize the importance of adequate stimulation for guaranteeing efficient killing of bacilli. In this particular case, the IFN-gamma and TNF were involved in the activation of macrophage bactericidal activity

Quality in management accounting: approach by activities in large companies

This study intends to contribute to the knowledge about the approach by activities, a management accounting method that promotes the quality of information. As specific objectives we have identified the following: to analyze the knowledge rate regarding the approach by activities, and identify whether there is a link between it and the financial officers’ characteristics; to analyze the utilization rate of the approach by activities, and the factors conditioning it; to analyze whether there is a link between a company’s features, and the use of the approach by activities. The data collection method used was the application of a survey to the financial officers of the largest Portuguese companies, which yielded 61 valid responses. The results found allowed us to conclude the following: the Time Driven Activity Based Costing is very little known and used in Portugal; there is a link between the knowledge of the approach by activities and the financial officers’ gender, age and educational background; there is a link between the use of the approach by activities and two company features: the legal form and the capital holding.info:eu-repo/semantics/acceptedVersio

Fertilização com uréia em superfície em pastagem irrigada e a volatilização de amônia.

A aplicação de uréia em superfície na pastagem pode ocasionar elevadas perdas de amônia por volatilização e uma das alternativas para minimizar esse efeito é a irrigação ou a precipitação logo após a adubação. O objetivo dessa pesquisa foi avaliar o efeito da aplicação de lâminas de água, após a adubação com uréia (75 kgN/ha) na superfície e a lanço em pastagem de colonião, nas perdas de N por volatilização. Foram realizados três experimentos em três épocas, verão, inverno e primavera. O delineamento experimental foi em faixas, em sistema de aspersão em linha, com cinco repetições. Os tratamentos foram quatro níveis de irrigação após a adubação com uréia, sendo três tratamentos com lâminas de água e um controle (sem irrigação). Um dos tratamentos consistia em elevar a umidade do solo à capacidade de campo e os outros dois eram lâminas de água intermediárias aos do controle e capacidade de campo, havendo variação conforme a estação do ano. No verão, a aplicação de apenas 3,2 mm de água elevou a umidade do solo para 52,4% da capacidade de água disponível e reduziu as perdas de N-NH3 para menos de 3,1 % do N aplicado, enquanto a ausência de irrigação provocou perdas de 30,5%. No inverno e na primavera a volatilização de N-NH3 foi baixa, mesmo na ausência de irrigação após a adubação. Na primavera, a irrigação com 16 mm de água elevou a umidade do solo à capacidade de campo e reduziu as perdas para 1,6 % do N aplicado, enquanto no controle as perdas foram de 5%