6 research outputs found
Defining the molecular response to trastuzumab, pertuzumab and combination therapy in ovarian cancer
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Allosteric modulation of G protein‐coupled receptors by amiloride and its derivatives. Perspectives for drug discovery?
No full textFunctionally distinct and selectively phosphorylated GPCR subpopulations co-exist in a single cell
Get PDFβ2-adrenergic receptor (β2AR) can be phosphorylated by G protein receptor kinases and second messenger-dependent kinases. Here, the authors demonstrate that these phosphorylation events are specific to functionally distinct and spatially segregated subpopulations of β2AR that co-exist in a single cell
