Innovations of wireless capsule robots in gastrointestinal endoscopy: a review

Gastrointestinal endoscopy as crucial observation procedure for detecting numerous critical disorders has many limitations with current tethered devices. Specialists recommended further investigation by Wireless Capsule Endoscopy (WCE) in which they investigate gastrointestinal tract by a capsule-sized robot equipped with out-body image transmitter. WCE is utilized in further observation of the small bowel for different disorders such as tumors, polyps, bleeding, and Crohn’s disease. Although numerous advances have been done in the last decade and the technology progress is so fast, some restrictions still remained in terms of visioning issues, orientation, drug delivery, biopsy, and others. Using passive motion, very time-consuming process, localization, and lack of movement control are the main challenges of researchers in this criteria. In this article, recent technological advancements in the area of WCE inspection are highlighted. As WCE inspection generally become the top priority for finding of gastrointestinal tract disorders, a comprehensive review has been considered to evaluate technologies and limitations in terms of technical specifications

Intention and Negligence as Elements of Illegality : A Study of the 'personale Unrechtsauffassung'

textabstractBackground: Gastrointestinal endoscopy plays a crucial role in the diagnosis and management of gastrointestinal disorders. When endoscopy is indicated during pregnancy, concerns about the effects on pregnancy outcome often arise. The aim of this study was to assess whether lower gastrointestinal endoscopies (LGEs) across all three trimesters of pregnancy affects pregnancy outcomes. Methods: A systematic literature search was performed using Embase (including MEDLINE), Medline OvidSP, Cochrane Central Register of Controlled Trials, Web-of-Science, Google scholar and Pubmed. All original research articles from 1990 until May 2014 involving pregnant women who underwent LGE for any indication were included. Adverse pregnancy events like spontaneous abortion, preterm birth and fetal demise were assessed for a temporal and etiological relation with the LGE. Results: In total, 5514 references were screened by two independent reviewers. Eighty-two references met the inclusion criteria and were selected. Two retrospective, controlled studies, one uncontrolled study and 79 case reports were identified. In the three studies, birth outcomes did not differ between women undergoing LGE during pregnancy, compared to women that had an indication for LGE but in whom LGE was not performed because of pregnancy. In 79 case reports, 92 patients are described who underwent 100 LGE's during pregnancy. LGEs performed in all trimesters (n = 32, 39 and 29) were both temporally and etiologically related to 1, 3 and 2 adverse events, respectively. Conclusion: Based on the available literature, this review concludes that lower gastrointestinal endoscopy during pregnancy is of low risk for mother and child in all three trimesters of pregnancy