Mental health impacts of flooding: a controlled interrupted time series analysis of prescribing data in England.

BACKGROUND: There is emerging evidence that people affected by flooding suffer adverse impacts on their mental well-being, mostly based on self-reports. METHODS: We examined prescription records for drugs used in the management of common mental disorder among primary care practices located in the vicinity of recent large flood events in England, 2011-2014. A controlled interrupted time series analysis was conducted of the number of prescribing items for antidepressant drugs in the year before and after the flood onset. Pre-post changes were compared by distance of the practice from the inundated boundaries among 930 practices located within 10 km of a flood. RESULTS: After control for deprivation and population density, there was an increase of 0.59% (95% CI 0.24 to 0.94) prescriptions in the postflood year among practices located within 1 km of a flood over and above the change observed in the furthest distance band. The increase was greater in more deprived areas. CONCLUSIONS: This study suggests an increase in prescribed antidepressant drugs in the year after flooding in primary care practices close to recent major floods in England. The degree to which the increase is actually concentrated in those flooded can only be determined by more detailed linkage studies

On a new conformal functional for simplicial surfaces

We introduce a smooth quadratic conformal functional and its weighted version $$W_2=\sum_e \beta^2(e)\quad W_{2,w}=\sum_e (n_i+n_j)\beta^2(e),$$ where $\beta(e)$ is the extrinsic intersection angle of the circumcircles of the triangles of the mesh sharing the edge $e=(ij)$ and $n_i$ is the valence of vertex $i$. Besides minimizing the squared local conformal discrete Willmore energy $W$ this functional also minimizes local differences of the angles $\beta$. We investigate the minimizers of this functionals for simplicial spheres and simplicial surfaces of nontrivial topology. Several remarkable facts are observed. In particular for most of randomly generated simplicial polyhedra the minimizers of $W_2$ and $W_{2,w}$ are inscribed polyhedra. We demonstrate also some applications in geometry processing, for example, a conformal deformation of surfaces to the round sphere. A partial theoretical explanation through quadratic optimization theory of some observed phenomena is presented.Comment: 14 pages, 8 figures, to appear in the proceedings of "Curves and Surfaces, 8th International Conference", June 201

Effects of N(2080)3/2−N(2080){3/2}^- and N(2270)3/2−N(2270)3/2^- molecules on K∗ΣK^\ast \Sigma photoproduction

In the present work, we re-analyze the available data for $\gamma p\to K^{\ast +}\Sigma^0$ and $\gamma p \to K^{\ast 0}\Sigma^+$ by considering the contributions from the $N(2080){3/2}^-$ and $N(2270)3/2^-$ molecules instead of any nucleon resonances in the $s$ channel, where the $N(2080)3/2^-$ was proposed to be a $K^\ast \Sigma$ molecule as the strange partner of the $P_c^+(4457)$ hadronic molecular state, and the $N(2270)3/2^-$ was assumed to be a $K^*\Sigma^*$ molecule as the strange partner of the $\bar{D}^\ast \Sigma^\ast_c$ bound states that are predicated as members in the same heavy-quark spin symmetry multiplet as the $P_c$ states. It turns out that all the available cross-section data can be well reproduced, indicating that the molecular structures of the possible $N(2080){3/2}^-$ and $N(2270)3/2^-$ states are compatible with the available data for $K^\ast\Sigma$ photoproduction reactions. Further analysis shows that for both $\gamma p\to K^{\ast +}\Sigma^0$ and $\gamma p \to K^{\ast 0}\Sigma^+$ reactions, the $N(2080){3/2}^-$ exchange provides dominant contributions to the cross-sections in the near-threshold energy region, and significant contributions from the $N(2270)3/2^-$ exchange to the cross-sections in the higher energy region are also found. Predictions of the beam asymmetry $\Sigma$, target asymmetry $T$, and recoil baryon asymmetry $P$ are presented and compared with those from our previous work. Measurements of the data on these observables are called on to further constrain the reaction mechanisms of $K^\ast\Sigma$ photoproduction reactions and to verify the molecular scenario of the $N(2080){3/2}^-$ and $N(2270)3/2^-$ states.Comment: 10 pages, 8 figure

An Evolutionarily Threat-Relevant Odor Strengthens Human Fear Memory.

Olfaction is an evolutionary ancient sense, but it remains unclear to what extent it can influence routine human behavior. We examined whether a threat-relevant predator odor (2-methyl-2-thiazoline) would contextually enhance the formation of human fear memory associations. Participants who learned to associate visual stimuli with electric shock in this predator odor context later showed stronger fear responses to the visual stimuli than participants who learned in an aversiveness-matched control odor context. This effect generalized to testing in another odor context, even after extinction training. Results of a separate experiment indicate that a possible biological mechanism for this effect may be increased cortisol levels in a predator odor context. These results suggest that innate olfactory processes can play an important role in human fear learning. Modulatory influences of odor contexts may partly explain the sometimes maladaptive persistence of human fear memory, e.g., in post-traumatic stress disorders

Graphene-based photovoltaic cells for near-field thermal energy conversion

Thermophotovoltaic devices are energy-conversion systems generating an electric current from the thermal photons radiated by a hot body. In far field, the efficiency of these systems is limited by the thermodynamic Schockley-Queisser limit corresponding to the case where the source is a black body. On the other hand, in near field, the heat flux which can be transferred to a photovoltaic cell can be several orders of magnitude larger because of the contribution of evanescent photons. This is particularly true when the source supports surface polaritons. Unfortunately, in the infrared where these systems operate, the mismatch between the surface-mode frequency and the semiconductor gap reduces drastically the potential of this technology. Here we show that graphene-based hybrid photovoltaic cells can significantly enhance the generated power paving the way to a promising technology for an intensive production of electricity from waste heat.Comment: 5 pages, 4 figure

Methods to estimate acclimatization to urban heat island effects on heat- and cold-related mortality

Background: Investigators have examined whether heat mortality risk is increased in neighborhoods subject to the urban heat island (UHI) effect but have not identified degrees of difference in susceptibility to heat and cold between cool and hot areas, which we call acclimatization to the UHI. Objectives: We developed methods to examine and quantify the degree of acclimatization to heat- and cold-related mortality in relation to UHI anomalies and applied these methods to London, UK. Methods: Case–crossover analyses were undertaken on 1993–2006 mortality data from London UHI decile groups defined by anomalies from the London average of modeled air temperature at a 1-km grid resolution. We estimated how UHI anomalies modified excess mortality on cold and hot days for London overall and displaced a fixed-shape temperature-mortality function (“shifted spline” model). We also compared the observed associations with those expected under no or full acclimatization to the UHI. Results: The relative risk of death on hot versus normal days differed very little across UHI decile groups. A 1°C UHI anomaly multiplied the risk of heat death by 1.004 (95% CI: 0.950, 1.061) (interaction rate ratio) compared with the expected value of 1.070 (1.057, 1.082) if there were no acclimatization. The corresponding UHI interaction for cold was 1.020 (0.979, 1.063) versus 1.030 (1.026, 1.034) (actual versus expected under no acclimatization, respectively). Fitted splines for heat shifted little across UHI decile groups, again suggesting acclimatization. For cold, the splines shifted somewhat in the direction of no acclimatization, but did not exclude acclimatization. Conclusions: We have proposed two analytical methods for estimating the degree of acclimatization to the heat- and cold-related mortality burdens associated with UHIs. The results for London suggest relatively complete acclimatization to the UHI effect on summer heat–related mortality, but less clear evidence for cold–related mortality