6 research outputs found

    Non-Parametric Search for Significant Variables of a Linear Model

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    Pharmaceutical Applications of a Multi-Stage Group Testing Method

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    Efficient Group Testing Algorithms with a Constrained Number of Positive Responses

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    Group testing is a well known search problem that consists in detecting the defective members of a set of objects O by performing tests on properly chosen subsets (pools) of the given set O. In classical group testing the goal is to find all defectives by using as few tests as possible. We consider a variant of classical group testing in which one is concerned not only with minimizing the total number of tests but aims also at reducing the number of tests involving defective elements. The rationale behind this search model is that in many practical applications the devices used for the tests are subject to deterioration due to exposure to or interaction with the defective elements. As an example, consider the leak testing procedures aimed at guaranteeing safety of sealed radioactive sources. Personnel involved in these procedures are at risk of being exposed to radiation whenever a leak in the tested sources is present. The number of positive tests admitted by a leak testing procedure should depend on the dose of radiation which is judged to be of no danger for the health. Obviously, the total number of tests should also be taken into account in order to reduce the costs and the work load of the safety personnel. In this paper we consider both adaptive and nonadaptive group testing and for both scenarios we provide almost matching upper and lower bounds on the number of “yes” responses that must be admitted by any strategy performing at most a certain number t of tests. The lower bound for the non adaptive case follows from the upper bound on the optimal size of a variant of d-cover free families introduced in this paper, which we believe may be of interest also in other contexts

    Subquadratic non-adaptive threshold group testing

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    We consider threshold group testing â a generalization of a well known and thoroughly examined problem of combinatorial group testing. In the classical setting, the goal is to identify a set of positive individuals in a population, by performing tests on pools of elements. The output of each test is an answer to the question: is there at least one positive element inside a query set Q? The threshold group testing is a natural generalization of this classical setting which arises when the answer to a test is positive if at least t > 0 elements under test are positive. We show that there exists a testing strategy for the threshold group testing consisting of (formula presented ) tests, for d positive items in a population of size N. For any value of the threshold t, we also provide a lower bound of order (formula presented). Our subquadratic bound shows a complexity separation with the classical group testing (which corresponds to t = 1) where Ω(d2logdN) tests are needed [25]. Next, we introduce a further generalization, the multi-threshold group testing problem. In this setting, we have a set of s > 0 thresholds, t1, t2, â¦, ts. The output of each test is an integer between 0 and s which corresponds to which thresholds get passed by the number of positives in the queried pool. Here, one may be interested in minimizing not only the number of tests, but also the number of thresholds which is related to the accuracy of the tests. We show the existence of two strategies for this problem. The first one of size (formula presented ) is an extension of the above-mentioned result. The second strategy is more general and works for a range of parameters. As a consequence, we show that (formula presented ) tests are sufficient for t ⤠d/2. Both strategies use respectively O(âd) and O(ât) thresholds
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