14 research outputs found
Ionic liquid 1-butyl-3-methylimidazolium bromide ([bmim]Br): a green and neutral reaction media for the efficient, catalyst-free synthesis of quinoxaline derivatives
Quinoxaline derivatives were produced in excellent yields and short reaction times via the condensation of 1,2-diamines with 1,2-diketones in the neutral ionic liquid 1-butyl-3-methylimidazolium bromide ([bmim]Br) under catalyst-free and microwave irradiation conditions
A developed chromogenic probe for determination of dual analyte with logic gates function and keypad-lock
A simple indicator displacement assay ensemble for rapid and selective determination and naked-eye detection of Cu<sup>2+</sup> and citrate through a novel diazo-based colorimetric chemosensor
Citrate as a naturally occurring ion with important biological roles, especially in metabolic cycles, and as an important biomarker in the early diagnosis of many diseases, including prostate cancer, has received special attention. In the present study, a novel, sensitive, fast and simple colorimetric bisazo-based chemosensor was developed for sequential determination and naked-eye detection of Cu2+ and citrate. UV-Vis spectroscopic studies showed that Reactive Red 141 (RR141) exhibits high selectivity and sensitivity towards Cu2+ in the presence of many other cations in deionised water (10 mmol L−1 MES(2-(N-morpholino)ethanesulfonic acid)/NaOH buffer solution, pH 6.0) and complex real samples as well. The obvious colorimetric response while interaction with copper and citrate is due to complexation between RR141 and Cu2+, and then the citrate detection occurred through metal transfer from the RR141-Cu2+ towards the citrate anion releasing RR141 via an indicator displacement route. The mechanism of detection has been carefully investigated using the semi-empirical calculation method of MM2 molecular mechanics. The proposed detection method for citrate ion has a detection limit of 0.15 µmol L−1 and a satisfactory linear range of 1.92–45.96 µmol L−1, which is consistent with the desired average diagnostic concentration in prostate cancer (less than 2 mmol L−1). Our studies’ results indicate the high capability of the developed chemical sensor for quantitative and qualitative citrate detection in various complex media, including biological and clinical real samples.</p
Bismuth triggered selective colorimetric naked-eye detection for oxalate ions based on bromopyrogallol red that works as a molecular keypad lock
Novel use of calmagite as a fast and easy colorimetric anion chemosensor and solid-state sensor for carbonate ion in running water
ChemInform Abstract: One-Pot Synthesis of N-Alkyl Purine and Pyrimidine Derivatives from Alcohols Using TsIm: A Rapid Entry into Carboacyclic Nucleoside Synthesis.
A convenient and efficient one-pot N-alkylation of nucleobases from alcohols using
N-(
p-toluenesulfonyl)imidazole (TsIm) is described. In this method, treatment of alcohols with a mixture of purine or pyrimidine nucleobase, TsIm, K
2CO
3, and triethylamine in refluxing DMF regioselectively furnishes the corresponding
N-alkyl nucleobases in good yields. This methodology is highly efficient for various structurally diverse primary alcohols.
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Silica-Supported 2,4,6-Trichloro-1,3,5-triazine as an Efficient Reagent for Direct Conversion of Carboxylic Acids to Amides Under Solvent-Free Conditions
JSCS–4054 Original scientific paper
Ionic liquid 1-butyl-3-methylimidazolium bromide ([bmim]Br): a green and neutral reaction media for the efficient, catalyst-free synthesis of quinoxaline derivative