7 research outputs found
Floxin, a resource for genetically engineering mouse ESCs
No full textWe describe a method for the highly efficient and precise targeted modification of gene trap loci in mouse embryonic stem cells (ESCs). Through the Floxin method, gene trap mutations were reverted and new DNA sequences inserted using Cre recombinase and a shuttle vector, pFloxin. Floxin technology is applicable to the existing collection of 24,149 compatible gene trap cell lines, which should enable high-throughput modification of many genes in mouse ESCs
An association study between the dymeclin gene and schizophrenia in the Japanese population
No full textThe pleiotropy associated with de novo variants in CHD4, CNOT3, and SETD5 extends to moyamoya angiopathy
No full textSetd5 haploinsufficiency alters neuronal network connectivity and leads to autistic-like behaviors in mice
No full text
