459 research outputs found
Semiclassical Analysis of M2-brane in AdS_4 x S^7 / Z_k
We start from the classical action describing a single M2-brane on AdS_4 x
S^7/ Z_k and consider semiclassical fluctuaitions around a static, 1/2 BPS
configuration whose shape is AdS_2 x S^1. The internal manifold S^7/ Z_k is
described as a U(1) fibration over CP^3 and the static configuration is wrapped
on the U(1) fiber. Then the configuration is reduced to an AdS_2 world-sheet of
type IIA string on AdS_4 x CP^3 through the Kaluza-Klein reduction on the S^1.
It is shown that the fluctuations form an infinite set of N=1 supermultiplets
on AdS_2, for k=1,2. The set is invariant under SO(8) which may be consistent
with N=8 supersymmetry on AdS_2. We discuss the behavior of the fluctuations
around the boundary of AdS_2 and its relation to deformations of Wilson loop
operator.Comment: 27 pages, v2: references added, v3: major revision including the
clarification of k=2 case, references added, version to appear in JHE
On semiclassical approximation for correlators of closed string vertex operators in AdS/CFT
We consider the 2-point function of string vertex operators representing
string state with large spin in AdS_5. We compute this correlator in the
semiclassical approximation and show that it has the expected (on the basis of
state-operator correspondence) form of the strong-coupling limit of the 2-point
function of single trace minimal twist operators in gauge theory. The
semiclassical solution representing the stationary point of the path integral
with two vertex operator insertions is found to be related to the large spin
limit of the folded spinning string solution by a euclidean continuation,
transformation to Poincare coordinates and conformal map from cylinder to
complex plane. The role of the source terms coming from the vertex operator
insertions is to specify the parameters of the solution in terms of quantum
numbers (dimension and spin) of the corresponding string state. Understanding
further how similar semiclassical methods may work for 3-point functions may
shed light on strong-coupling limit of the corresponding correlators in gauge
theory as was recently suggested by Janik et al in arXiv:1002.4613.Comment: 19 pages, 1 figure; minor corrections, references added, footnote
below eq. (4.5) adde
Correlators of Vertex Operators for Circular Strings with Winding Numbers in AdS5xS5
We compute semiclassically the two-point correlator of the marginal vertex
operators describing the rigid circular spinning string state with one large
spin and one windining number in AdS_5 and three large spins and three winding
numbers in S^5. The marginality condition and the conformal invariant
expression for the two-point correlator obtained by using an appropriate vertex
operator are shown to be associated with the diagonal and off-diagonal Virasoro
constraints respectively. We evaluate semiclassically the three-point
correlator of two heavy circular string vertex operators and one zero-momentum
dilaton vertex operator and discuss its relation with the derivative of the
dimension of the heavy circular string state with respect to the string
tension.Comment: 16 pages, LaTeX, no figure
Transumbilical Totally Laparoscopic Single-Port Nissen Fundoplication: A New Method of Liver Retraction: The Istanbul Technique
Mustafa Kemal Ataturk, founder of the Turkish Republic, had guarded many German scientists of a Jewish descent before the Second World War. Dr. Rudolf Nissen was one of the outstanding surgeons who had served in the Turkish university hospitals. He had created an antireflux procedure which is named after his own name while he was working in our clinic, the CerrahpaAYa Hospital. From a laparoscopic approach, the Nissen fundoplication was the gold standard intervention for the surgical treatment of gastroesophageal reflux disease (GERD). Currently, video laparoscopic surgery is evolving quickly with the guidance of new technology. Single-port (SP) laparoscopic transumbilical surgery is one of the newest branches of advanced laparoscopy
Correlation function of null polygonal Wilson loops with local operators
We consider the correlator of a light-like polygonal Wilson loop
with n cusps with a local operator (like the dilaton or the chiral primary
scalar) in planar N =4 super Yang-Mills theory. As a consequence of conformal
symmetry, the main part of such correlator is a function F of 3n-11 conformal
ratios. The first non-trivial case is n=4 when F depends on just one conformal
ratio \zeta. This makes the corresponding correlator one of the simplest
non-trivial observables that one would like to compute for generic values of
the `t Hooft coupling \lambda. We compute F(\zeta,\lambda) at leading order in
both the strong coupling regime (using semiclassical AdS5 x S5 string theory)
and the weak coupling regime (using perturbative gauge theory). Some results
are also obtained for polygonal Wilson loops with more than four edges.
Furthermore, we also discuss a connection to the relation between a correlator
of local operators at null-separated positions and cusped Wilson loop suggested
in arXiv:1007.3243.Comment: 36 pages, 2 figure
Continuation for thin film hydrodynamics and related scalar problems
This chapter illustrates how to apply continuation techniques in the analysis
of a particular class of nonlinear kinetic equations that describe the time
evolution through transport equations for a single scalar field like a
densities or interface profiles of various types. We first systematically
introduce these equations as gradient dynamics combining mass-conserving and
nonmass-conserving fluxes followed by a discussion of nonvariational amendmends
and a brief introduction to their analysis by numerical continuation. The
approach is first applied to a number of common examples of variational
equations, namely, Allen-Cahn- and Cahn-Hilliard-type equations including
certain thin-film equations for partially wetting liquids on homogeneous and
heterogeneous substrates as well as Swift-Hohenberg and Phase-Field-Crystal
equations. Second we consider nonvariational examples as the
Kuramoto-Sivashinsky equation, convective Allen-Cahn and Cahn-Hilliard
equations and thin-film equations describing stationary sliding drops and a
transversal front instability in a dip-coating. Through the different examples
we illustrate how to employ the numerical tools provided by the packages
auto07p and pde2path to determine steady, stationary and time-periodic
solutions in one and two dimensions and the resulting bifurcation diagrams. The
incorporation of boundary conditions and integral side conditions is also
discussed as well as problem-specific implementation issues
Preliminary Surgical Results of Single-Incision Transumbilical Laparoscopic Bariatric Surgery
Neural Substrate of Cold-Seeking Behavior in Endotoxin Shock
Systemic inflammation is a leading cause of hospital death. Mild systemic inflammation is accompanied by warmth-seeking behavior (and fever), whereas severe inflammation is associated with cold-seeking behavior (and hypothermia). Both behaviors are adaptive. Which brain structures mediate which behavior is unknown. The involvement of hypothalamic structures, namely, the preoptic area (POA), paraventricular nucleus (PVH), or dorsomedial nucleus (DMH), in thermoregulatory behaviors associated with endotoxin (lipopolysaccharide [LPS])-induced systemic inflammation was studied in rats. The rats were allowed to select their thermal environment by freely moving in a thermogradient apparatus. A low intravenous dose of Escherichia coli LPS (10 µg/kg) caused warmth-seeking behavior, whereas a high, shock-inducing dose (5,000 µg/kg) caused cold-seeking behavior. Bilateral electrocoagulation of the PVH or DMH, but not of the POA, prevented this cold-seeking response. Lesioning the DMH with ibotenic acid, an excitotoxin that destroys neuronal bodies but spares fibers of passage, also prevented LPS-induced cold-seeking behavior; lesioning the PVH with ibotenate did not affect it. Lesion of no structure affected cold-seeking behavior induced by heat exposure or by pharmacological stimulation of the transient receptor potential (TRP) vanilloid-1 channel (“warmth receptor”). Nor did any lesion affect warmth-seeking behavior induced by a low dose of LPS, cold exposure, or pharmacological stimulation of the TRP melastatin-8 (“cold receptor”). We conclude that LPS-induced cold-seeking response is mediated by neuronal bodies located in the DMH and neural fibers passing through the PVH. These are the first two landmarks on the map of the circuitry of cold-seeking behavior associated with endotoxin shock
Experimental glomerulonephritis induced by hydrocarbon exposure: A systematic review
BACKGROUND: Much epidemiological evidence suggests that hydrocarbon exposure may induce glomerulonephritis and worsen its course in many patients. The mechanisms are unknown, however, no specific microscopic pattern has been identified, and it has also been argued that hydrocarbon exposure causes tubular damage mainly. Studying experimental animals may best answer these questions, and as no systematic review of glomerulonephritis produced experimentally by hydrocarbon exposure has been performed previously, I found it relevant to search for and analyse such studies. METHODS: Animal experiments having mimicked human glomerulonephritis by hydrocarbon exposure were sought on Medline and Toxnet RESULTS: Twenty-six experiments using thirteen different hydrocarbons were identified. Several human subtypes were observed including IgA nephritis, mesangial, proliferative and extracapillary glomerulonephritis, focal and focal-segmental sclerosis, minimal change nephropathy, anti-GBM and anti-TBM nephritis, and glomerulonephritis associated with peiarteritis nodosa. Glomerular proteinuria was seen in 10/12 experiments that included urine analyses, and renal failure in 5/8 experiments that included measurements of glomerular function. All experiments resulted in various degrees of tubular damage as well. In most studies, where the animals were examined at different times during or after the exposure, the renal microscopic and functional changes were seen immediately, whereas deposits of complement and immunoglobulins appeared late in the course, if at all. CONCLUSION: These experiments are in accord with epidemiological evidence that hydrocarbon exposure may cause glomerulonephritis and worsen renal function. Probable mechanisms include an induction of autologous antibodies and a disturbance of normal immunological functions. Also, tubular damage may increase postglomerular resistance, resulting in a glomerular deposition of macromolecules. In most models a causal role of glomerular immune complex formation was unlikely, but may rather have been a secondary phenomenon. As most glomerulonephritis subgroups were seen and as some of the hydrocarbons produced more than one subgroup, the microscopic findings in a patient cannot be used as a clue to the causation of his disease. By the same reason, the lack of a specific histological pattern in patients with glomerulonephritis assumed to have been caused by hydrocarbon exposure is not contradictive
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