Quantum-enhanced magnetometry by phase estimation algorithms with a single artificial atom

Phase estimation algorithms are key protocols in quantum information processing. Besides applications in quantum computing, they can also be employed in metrology as they allow for fast extraction of information stored in the quantum state of a system. Here, we implement two suitably modified phase estimation procedures, the Kitaev and the semiclassical Fourier-transform algorithms, using an artificial atom realized with a superconducting transmon circuit. We demonstrate that both algorithms yield a flux sensitivity exceeding the classical shot-noise limit of the device, allowing one to approach the Heisenberg limit. Our experiment paves the way for the use of superconducting qubits as metrological devices which are potentially able to outperform the best existing flux sensors with a sensitivity enhanced by few orders of magnitude

Isovector soft dipole mode in 6Be

By using the 1H(6Li,6Be)n charge-exchange reaction, continuum states in 6Be were populated up to E_t=16 MeV, E_t being the 6Be energy above its three-body decay threshold. In kinematically complete measurements performed by detecting alpha+p+p coincidences, an E_t spectrum of high statistics was obtained, containing approximately ~5x10^6 events. The spectrum provides detailed correlation information about the well-known 0^+ ground state of 6Be at E_t=1.37 MeV and its 2^+ state at E_t=3.05 MeV. Moreover, a broad structure extending from 4 to 16 MeV was observed. It contains negative parity states populated by Delta L=1 angular momentum transfer without other significant contributions. This structure can be interpreted as a novel phenomenon, i.e. the isovector soft dipole mode associated with the 6Li ground state. The population of this mode in the charge-exchange reaction is a dominant phenomenon for this reaction, being responsible for about 60% of the cross section obtained in the measured energy range.Comment: 8 pages, 7 figure

ИЗМЕНЕНИЕ КЛИНИЧЕСКОЙ КАРТИНЫ АЛКОГОЛЬНОЙ ЗАВИСИМОСТИ НА ФОНЕ ЛЕЧЕНИЯ НАЛТРЕКСОНОМ ДЛИТЕЛЬНОГО ДЕЙСТВИЯ В ИНЪЕКЦИОННОЙ ФОРМЕ: СЛУЧАЙ ИЗ ПРАКТИКИ

Alcoholism is a severe chronic mental illness, often subordinating all aspects of the patient’s life and quickly leading to social degradation. In recent years we observed a certain change in the attitude towards the classical therapeutic approach, which implies a complete abstention from alcohol intake. This was due to the research on pharmacological agents that can affect the brain reinforcement system, thereby reducing craving and decreasing the amount of alcohol consumed. This article describes a clinical case of changing the pattern of alcohol abuse during the use of opioid receptor antagonist naltrexone in the form of injections for the treatment of a patient with severe alcohol dependence, resistant to psychopharmacotherapy. The effectiveness and duration of the treatment course is determined primarily by patients’ motivation or by the interest of persons close to the patient.В данной статье описан клинический случай применения антагониста опиоидных рецепторов налтрексона пролонгированного действия в форме инъекций для лечения пациента с тяжелым случаем алкогольной зависимости, резистентной к психофармакотерапии. Эффективность и продолжительность курса лечения, определяется в первую очередь, мотивацией больных либо заинтересованностью близких пациенту лиц

ИЗМЕНЕНИЕ КЛИНИЧЕСКОЙ КАРТИНЫ АЛКОГОЛЬНОЙ ЗАВИСИМОСТИ НА ФОНЕ ЛЕЧЕНИЯ НАЛТРЕКСОНОМ ДЛИТЕЛЬНОГО ДЕЙСТВИЯ В ИНЪЕКЦИОННОЙ ФОРМЕ: СЛУЧАЙ ИЗ ПРАКТИКИ

Alcoholism is a severe chronic mental illness, often subordinating all aspects of the patient’s life and quickly leading to social degradation. In recent years we observed a certain change in the attitude towards the classical therapeutic approach, which implies a complete abstention from alcohol intake. This was due to the research on pharmacological agents that can affect the brain reinforcement system, thereby reducing craving and decreasing the amount of alcohol consumed. This article describes a clinical case of changing the pattern of alcohol abuse during the use of opioid receptor antagonist naltrexone in the form of injections for the treatment of a patient with severe alcohol dependence, resistant to psychopharmacotherapy. The effectiveness and duration of the treatment course is determined primarily by patients’ motivation or by the interest of persons close to the patient.В данной статье описан клинический случай применения антагониста опиоидных рецепторов налтрексона пролонгированного действия в форме инъекций для лечения пациента с тяжелым случаем алкогольной зависимости, резистентной к психофармакотерапии. Эффективность и продолжительность курса лечения, определяется в первую очередь, мотивацией больных либо заинтересованностью близких пациенту лиц

Seborrheic dermatitis in patients with psychoneurological disorders

Seborrheic dermatitis (SD) is a chronic inflammatory skin disease. Genetic predisposition, hormonal disorders, neurohumoral, metabolic, and immune changes play an important role in the development of this disease. All these factors lead to activation of pathogenic microbial flora and development of the skin rash characteristic of SD. Malassezia fungus is currently believed to be the main etiological factor in the development of SD. In this paper, the authors draw attention to the characteristic features of seborrheic dermatitis in patients with neuropsychiatric disorders. Authors report their own observations. The use of Nizoral shampoo twice a week for 1 month was recommended as a topical therapy. In 58.3% of patients, no symptoms of seborrheic dermatitis were observed 1 month after administration of Nizoral shampoo. In 41.7% of patients, there was no itching and peeling, but minor hyperemia at the areas of rash was preserved. After the end of therapy, a two-month-long remission was observed in2/3 of patients, while others had only slight peeling. In view of the intense sebostatic effect of 2% ketoconazole, it can be recommended for the use in the form of shampoo for treatment and prevention of seborrheic dermatitis in patients at specialized institutions. The ease of use greatly facilitates the care for patients with psychoneurological disorders. © 2015, Media Sphera Publishing Group. All rights reserved

Analysis of the relationship between skin and emotional disorders in patients with psoriasis

107 patients (34 female and 73 male) diagnosed with “generalized psoriasis vulgaris, exudative form, progressive stage” were evaluated for the levels of anxiety and depression. These measurements were carried out along with psychiatrist interview, taking into consideration anamnestic and status information. 67,3% of patients unhesitatingly marked that a previous psychological trauma had caused the current exacerbation of psoriasis. The study reveals interrelationship between the psychiatric and somatic components of psoriasis. We managed to reach marked remission in 19 patients using low doses of psychotropic drugs along with primary dermatological treatment.107 пациентов (34 женщины и 73 мужчины) с диагнозом “генерализованный вульгарный псориаз, экссудативная форма, прогрессирующая стадия” были оценены по уровню тревожности и депрессии. Эти измерения проводились наряду с опросом психиатра с учетом анамнестической и статусной информации. 67,3% пациентов без колебаний отметили, что предыдущая психологическая травма вызвала нынешнее обострение псориаза. В ходе исследования выявлена взаимосвязь между психиатрическим и соматическим компонентами псориаза. Нам удалось достичь выраженной ремиссии у 19 пациентов, применявших низкие дозы психотропных препаратов наряду с первичным дерматологическим лечением

Связь между однонуклеотидной заменой T > C в гене MIR22 и развитием псориаза

Psoriasis is a multifactorial polygenic disease. Genetic markers of psoriasis still remain undetected. At the same time, the combined course of psoriasis with anxiety and depressive disorders suggests the participation of anxiety-associated genetic markers in the development of dermatosis. The aim of the study. To evaluate the association between single nucleotide change T > C in the gene MIR22 and psoriasis. Material and methods. The main group consisted of 88 patients with psoriasis (L40 according to the International Classification of Diseases-10), the control group - 165 unexplored persons. Genotyping was performed by using polymerase chain reaction - polymorphism of restriction DNA fragment lengths. Statistical analysis was processed using WinPepi, a two-way Fisher test. Results. Found the connection of TT genotype (replacement of T > C) with psoriasis (p = 0.030). The mechanisms of the identified link require further study.Псориаз - многофакторное полигенное заболевание. Генетические маркеры псориаза до сих пор не выявлены. В то же время сочетанное течение псориаза с тревожными и депрессивными расстройствами позволяет предположить участие в развитии дерматоза ассоциированных с тревожностью генетических маркеров. Цель исследования: оценить связь между однонуклеотидной заменой T > C в гене MIR22 и псориазом. Материал и методы. Основную группу составили 88 пациентов с псориазом (L40 согласно Международной классификации болезней - 10), контрольную - 165 необследованных лиц. Генотипирование проводили с использованием полимеразной цепной реакции - полиморфизма длин рестрикционных фрагментов ДНК. Статистический анализ осуществляли с помощью программы WinPepi, двустороннего критерия Фишера. Результаты. Обнаружена ассоциация генотипа ТТ (замена T > C) с псориазом (p = 0,030). Механизмы выявленной связи требуют дальнейшего изучения

Some problems of the teaching of organic chemistry in universities of Russia

[No abstract available