User guide for the Biosphere Isotope Domains GB (Version 1) dataset and web portal

This report is a user guide for the Biosphere Isotope Domains GB (V1) dataset, which includes (1) a GIS layer for strontium, sulphur and oxygen isotopes (2) datasets of strontium and sulphur isotope measurements from samples across the Great Britain - published separately and available via BGS and (3) a web portal for viewing and querying the data. A description of the data, methodology and assumptions used in the construction of the Biosphere Isotope Domains GB map is included in the associated publications for strontium (Evans, 2018) and sulphur (Chenery, 2018). The primary application of such datasets is for determining the provenance of skeletal material; although the data may also be of use in modern traceability studies of fauna and flora

Spin fluctuations in the quasi-two dimensional Heisenberg ferromagnet GdI_2 studied by Electron Spin Resonance

The spin dynamics of GdI_2 have been investigated by ESR spectroscopy. The temperature dependences of the resonance field and ESR intensity are well described by the model for the spin susceptibility proposed by Eremin et al. [Phys. Rev. B 64, 064425 (2001)]. The temperature dependence of the resonance linewidth shows a maximum similar to the electrical resistance and is discussed in terms of scattering processes between conduction electrons and localized spins.Comment: to be published in PR

Toxic oxygen metabolite production by circulating phagocytic cells in inflammatory bowel disease.

To investigate the possibility that the oxidative capacity of phagocytic cells may be defective in inflammatory bowel disease, toxic oxygen metabolite production by circulating neutrophils and monocytes has been measured by luminol dependent chemiluminescence. Neutrophils from patients with Crohn's disease and ulcerative colitis produced significantly lower chemiluminescent responses after chemotactic stimulation with formylmethionylleucylphenylalanine (fMLP) than neutrophils from control patients, p = 0.018 and 0.043 respectively. Chemiluminescent responses of neutrophils from patients with inflammatory bowel disease, however, were similar to control responses when cells were stimulated with latex beads or phorbol myristate acetate. Monocytes from patients with Crohn's disease produced significantly greater levels of chemiluminescence than control monocytes when stimulated with either fMLP (p less than 0.002), phorbol myristate acetate (p less than 0.0005) or latex beads (p less than 0.002). Monocytes from patients with ulcerative colitis also produced significantly greater levels of chemiluminescence than controls when stimulated with latex beads (p less than 0.5) or phorbol myristate acetate (p less than 0.0005), although there was no difference in the level of chemiluminescence in response to fMLP. These results exclude a generalised defect in phagocytic cell oxidase activity in inflammatory bowel disease and suggest that circulating monocytes are 'activated'