Biomedical and therapeutic applications of biosurfactants

During the last years, several applications of biosurfactants with medical purposes have been reported. Biosurfactants are considered relevant molecules for applications in combating many diseases and as therapeutic agents due to their antibacterial, antifungal and antiviral activities. Furthermore, their role as anti-adhesive agents against several pathogens illustrate their utility as suitable anti-adhesive coating agents for medical insertional materials leading to a reduction of a large number of hospital infections without the use of synthetic drugs and chemicals. Biomedical and therapeutic perspectives of biosurfactants applications are presented and discussed in this chapter

Sintering of compound nonwovens by forced convection of hot air

Sintering and interlocking of model nonwoven materials composed of a mixture of polycaprolactone (PCL) and polyacrylonitrile (PAN) fibers by means of forced convection of hot air through their pores is studied experimentally and theoretically. PCL has a much lower melting point than PAN, and the air temperature was sufficiently high to melt the former, while the latter stayed solid. These molten PCL fibers became a binder and conglutinated the PAN matrix, enhancing stiffness. This was demonstrated by measuring the effect of heat treatment on the resulting Young’s modulus of these compound nonwovens, as well as by the corresponding micro-morphological changes revealed by scanning electron microscopy. It was also shown that heating past the melting point of the binding fibers (PCL) would not further increase stiffness of the nonwovens, neither would heating for longer periods of times. A theoretical model describing the heating process was developed and tested experimentally. The model was verified using poly(ethylene terephthalate) PET nonwovens, which revealed good agreement of the data with the theoretical predictions