INTESTINAL ROTATION AND FIXATION ABNORMALITIES IN CHILDREN — CLINICAL COURSE, DIAGNOSIS AND TREATMENT APPROACHES

The article elucidates current opinion on embryogenesis and anatomical variants of intestinal rotation and fixation abnormalities (IRFA) in children describing signs and symptoms, clinical course and methods of diagnostics in 83 patients (age 0–9 years old). The authors emphasize characteristic features of manifestation and clinical course in connection with anatomical variant and age and consider possible treatment approaches.Key words: children, intestine, abnormal rotation and fixation.</strong

INTESTINAL ROTATION AND FIXATION ABNORMALITIES IN CHILDREN — CLINICAL COURSE, DIAGNOSIS AND TREATMENT APPROACHES

The article elucidates current opinion on embryogenesis and anatomical variants of intestinal rotation and fixation abnormalities (IRFA) in children describing signs and symptoms, clinical course and methods of diagnostics in 83 patients (age 0–9 years old). The authors emphasize characteristic features of manifestation and clinical course in connection with anatomical variant and age and consider possible treatment approaches.Key words: children, intestine, abnormal rotation and fixation

NEW CONCEPT OF ETIOPATHOGENESIS OF INFANT'S CHRONIC CONSTIPATION AND TREATMENT PRINCIPLES

Basing upon the study of conjunctive tissue frame and unstriped muscles of colon from autopsy material, as well as analysis of over 2000 clinical observations the authors set forth a new concept of etiopathogenesis of infant's chronic constipations by interpreting the functional disorders as a consequence of genetically determined status of conjunctive tissue frame. principles of conservative therapy and indications to surgery correction are considered.Key words: chronic constipation, etiology and pathogenesis, treatment, lactulose, surgical intervention, children