Basing upon the study of conjunctive tissue frame and unstriped muscles of colon from autopsy material, as well as analysis of over 2000 clinical observations the authors set forth a new concept of etiopathogenesis of infant's chronic constipations by interpreting the functional disorders as a consequence of genetically determined status of conjunctive tissue frame. principles of conservative therapy and indications to surgery correction are considered.Key words: chronic constipation, etiology and pathogenesis, treatment, lactulose, surgical intervention, children