CROSS-SECTIONS CALCULATION FOR THE PROCESS e-(P1)+ e+(P2)-> H- i(P2)+ H- j(P14)+ X0i(P5)

The cross-sections (?), in electron (e-) positron (e+) collision, is calculated over range of center of mass energy(s) for the process: 12 e-P1+e+P3. Please find more detail in the PDF full content.Keywords: Higgs bosons; neutralinos.

Creation of Two Charginos and Neutralino Via Different Propagators

We investigated the creation of two Charginos.......... Keywords: Chargino, neutralino and Higgs boson DOI: 10.7176/APTA/84-02 Publication date:August 31st 202

Advancing nursing? Master's level nurses in Jordan

The aim of the study was to examine the extent to which advanced nursing practice was evident in Jordan, with a particular focus on the contribution of Master’s level nurses to advancing practice. It also aimed at understanding the drivers for developing its roles and the factors which might facilitate or hinder their implementation. The study used an ethnographic design in which qualitative and quantitative methods of data collection were used. The study comprised two stages. The first stage involved interviewing key stakeholders and surveying M-level nurses. Stage two involved interviewing and observing M-level nurses working in clinical practice in five Jordanian hospitals and interviewing the main stakeholders with whom those nurses had contact. Three themes emerged from the data: understanding advanced nursing practice, becoming am M-level nurse, and being an M-level nurse. The analysis showed that there was no clear notion of advanced nursing practice in Jordan, although participants did describe a number of different elements of advanced practice. The analysis also revealed that nurses undertake Master’s degrees for professional and self-development reasons. The most frequently cited benefits from M-level education that reflected on practice were the enhancement of cognitive abilities, including critical thinking, problem solving and the questioning of practice, the use of research skills and in-service training. The area with least change was that of the development of new practical skills. The data also suggested that a change of job title or job description, after gaining a Master’s degree, reflects the movement of M-level nurses away from direct patient care to non-direct patient care. Several factors were identified as facilitating or hindering the development of the role of M-level nurses in practice. These were organisational factors, professional factors, and personal attributes. The most significant factors were lack of recognition of the M-level nurse, and the subservient role of the nurse in Jordanian society

Synthesis of 5-Fluorouracil Derivatives as Possible Mutual Prodrugs with Meloxicam and Ibuprofen for Targeting Cancer Tissues

In the present study, five derivatives have been designed to be synthesized as possible mutual prodrugs for 5-Fluorouracil (5-FU) and non steroidal anti-inflammatory drugs (NSAIDs) to selectively deliver the drugs into the cancer cells. The synthesis of the target compounds were accomplished following multistep reaction procedures, the chemical reaction followed up and the purity of the products were checked by TLC. The structure of the final compounds and their intermediates were confirmed by their melting points, infrared spectroscopy and elemental microanalysis, the hydrolysis of compound III was studied using HPLC technique. According to the results mentioned above, compounds (I−V) can be good candidates as possible mutual prodrugs of 5-FU and NSAIDs that can selectively deliver the parent drugs into the cancer cells by the effect of enzymes that elevated in tumor tissues compared with normal tissues. Key wards: Anticancer, 5-Fluorouracil, NSAIDs, prodrug.

Utility of (MgO)12 nanocage as a chemical sensor for recognition of amphetamine drug: A computational inspection

DFT calculations on sensor-drug interactions are necessary for understanding binding mechanisms, predicting sensor performance, evaluating stability and reactivity, and rational design of sensor materials. We scrutinized the adsorption of amphetamine (AFE) on the pure magnesium oxide nano-cage (MgONC) by applying density functional theory. All geometries and single point energy computations were optimized at M06–2X/6–311 G (d, p). Furthermore, we performed an analysis of the natural bond orbital (NBO) and evaluated the values of partial natural charges. Additionally, we investigated donor-acceptor (D-A) interactions and examined the Wiberg bond index (WBI) in greater depth. The MgONC was capable of adsorbing AFE with greater strength with the energy of adsorption (Eads) of −48.19 kcal/mol (for stable configurations). Moreover, the NBO method demonstrated more effective D-A interactions between AFE and the MgONC. Based on the computations, for the most stable configuration, there was a substantial alteration in the HOMO-LUMO gap of the MgONC following the drug adsorption, thus increasing the electrical conductance (EC) of the MgONC. The sensing mechanism is related to the gap difference, which depends on the change in the EC. We adopted the conventional transition state theory for the prediction of recovery time. The computations indicated that the MgONC+ AFE configuration had a short recovery time for the desorption of AFE. Finally, based on our findings, we could conclude that the MgONC is an appropriate choice for the improvement of effective AFE sensors. DFT study of drug sensors will focus on enhancing sensitivity, selectivity, and stability while exploring novel materials and optimizing performance through theoretical simulations and analysis

Temperature-based prediction and validation of pink bollworm, Pectinophora gossypiella infestation on cotton crop

Pink bollworm Pectinophora gossypiella infestation on cotton now a days found to be a major alarm to cotton crop in Pakistan. The effect of past and future temperatures climatic factors on the infestation rate of pink bollworm needs to be extensively studied. Field visits were organized in different areas across 17 main districts of Punjab, Pakistan, for eight consecutive years from 2012 to 2019. Based on past data, the pink bollworm infestation rate for the year 2040 was estimated. Our results showed an extensive infestation of pink bollworm on cotton throughout the visited locations between 0.1 and 35.7 % range above the economic threshold level, that cause reasonable cotton productivity losses. Based on the results of historical data of infestation rate, the nine of the 17 districts (53 %), Bahawalnagar, Bahawalpur, Faisalabad, Jahang, Mianwali, Multan, Muzaffargarh, Rahimyar Khan, and Lodhran, showed significantly (p < 0.05) higher pink bollworm infestation rate than the other cotton-growing areas. Moreover, the systematic increase level of pink bollworm infestation was predicted in 2040, especially in the five districts, Bhakar, Jahang, Khanewal, Faisalabad, and Vehari. Considering the importance of biological parameters, different temperature regimes (21 °C, 28 °C, and 35 °C) were tested for the validity of temperature-based prediction. Our results showed that growth capacity of P. gossypiella were increased at 28 °C. It revealed that, variation in weather due to current climatic condition with decreases of temperature increases P. gossypiella infestation on cotton crop. In this investigation, the effects of a severe outbreak of pink bollworm infections in Punjab's cotton-growing regions are discussed