1,006 research outputs found
Finite Word Length FIR Filter Design Using Integer Programming Over a Discrete Coefficient Space
The article of record as published may be found at http://dx.doi.org/10.1109/TASSP.1982.1163925Published in: IEEE Transactions on Acoustics, Speech, and Signal Processing (Volume: 30 , Issue: 4 , Aug 1982)It is demonstrated that the improvement achieved by using integer programming over simple coefficient rounding in the design of finite impulse response (FIR) filters with discrete coefficients is most significant when the discrete coefficient space is the powers-of-two space or when a specification is to be met with a given coefficient word length by increasing the filter length. Both minimax and least square error criteria are considered
Clash of the Paladins: India's Hindu-nationalism in decline?
Hindu-nationalism is generally portrayed by most observers as the largest threat to India's democracy
Expression of MUC5AC and MUC5B mucins in normal and cystic fibrosis lung
AbstractHypersecretion of airway mucus is a characteristic feature of chronic airway diseases like cystic fibrosis (CF) and leads via impairment of the muco-ciliary clearance and bacterial superinfection to respiratory failure. The major components of the mucus matrix forming family of mucins in the airways are MUC5AC and MUC5B. To investigate the expression of these glycoproteins in CF, immunohistochemistry was carried out on trachea, bronchi and peripheral lung obtained from CF patients and compared to normal lung tissues. MUC5AC immunohistochemistry demonstrated signals in goblet cells of the epithelial lining. Also, goblet cells inside glandular secretory ducts revealed MUC5AC-positive staining. In comparison to those from normal subjects, CF sections were characterized by inflammatory changes and goblet cell hyperplasia, resulting in increased numbers of MUC5AC-positive cells. Immunohistochemical staining for MUC5B showed abundant staining of submucosal glands and epithelial goblet cells. Inside the glands, the immunoreactivity was restricted to glandular mucous cells. MUC5AC and MUC5B are expressed in the same histological pattern in CF compared to normal tissues with an increase of MUC5AC-positive cells due to goblet cell hyper- and metaplasia
The Care Homes Use of Medicines Study: prevalence, causes and potential harm of medication errors in care homes for older people
Introduction: Care home residents are at particular risk from medication errors, and our objective was to determine the prevalence and potential harm of prescribing, monitoring, dispensing and administration errors in UK care homes, and to identify their causes.
Methods: A prospective study of a random sample of residents within a purposive sample of homes in three areas. Errors were identified by patient interview, note review, observation of practice and examination of dispensed items. Causes were understood by observation and from theoretically framed interviews with home staff, doctors and pharmacists. Potential harm from errors was assessed by expert judgement.
Results: The 256 residents recruited in 55 homes were taking a mean of 8.0 medicines. One hundred and seventy-eight (69.5%) of residents had one or more errors. The mean number per resident was 1.9 errors. The mean potential harm from prescribing, monitoring, administration and dispensing errors was 2.6, 3.7, 2.1 and 2.0 (0 = no harm, 10 = death), respectively. Contributing factors from the 89 interviews included doctors who were not accessible, did not know the residents and lacked information in homes when prescribing; home staff’s high workload, lack of medicines training and drug round interruptions; lack of team work among home, practice and pharmacy; inefficient ordering systems; inaccurate medicine records and prevalence of verbal communication; and difficult to fill (and check) medication administration systems.
Conclusions: That two thirds of residents were exposed to one or more medication errors is of concern. The will to improve exists, but there is a lack of overall responsibility. Action is required from all concerned
An Extended Zel'dovich Model for the Halo Mass Function
A new way to construct a fitting formula for the halo mass function is
presented. Our formula is expressed as a solution to the modified Jedamzik
matrix equation that automatically satisfies the normalization constraint. The
characteristic parameters expressed in terms of the linear shear eigenvalues
are empirically determined by fitting the analytic formula to the numerical
results from the high-resolution N-body simulation and found to be independent
of scale, redshift and background cosmology. Our fitting formula with the
best-fit parameters is shown to work excellently in the wide mass-range at
various redshifts: The ratio of the analytic formula to the N-body results
departs from unity by up to 10% and 5% over 10^{11}<= M/(M_sun/h)<= 5x10^{15}
at z=0,\ 0.5 and 1 for the FoF-halo and SO-halo cases, respectively.Comment: Accepted for publication in JCAP; 19pages, 9 figures, significantly
revised, discussion on the limitation of our model adde
Terahertz Radar Cross Section Characterization using Laser Feedback Interferometry with a Quantum Cascade Laser
Radar cross section (RCS) measurements of complex, large objects are usually performed on scale models so that the measurement is carried out in a well-controlled environment. This letter explores the feasibility of RCS measurement using a terahertz quantum cascade laser via laser feedback interferometry. Numerical simulations show that the RCS information embedded in the non-linear interferometric signals obtained from simple targets can be retrieved through numerical fitting of the well-known excess phase equation. The method is validated experimentally using a terahertz quantum cascade laser and the results are well matched with those obtained from numerical simulations
Escape from washing out of baryon number in a two-zero-texture general Zee model compatible with the large mixing angle MSW solution
We propose a two-zero-texture general Zee model, compatible with the large
mixing angle Mikheyev-Smirnov-Wolfenstein solution. The washing out of the
baryon number does not occur in this model for an adequate parameter range. We
check the consistency of a model with the constraints coming from flavor
changing neutral current processes, the recent cosmic microwave background
observation, and the Z-burst scenario.Comment: 22 pages, 2 eps figures, Type set revtex
New mechanism to cross the phantom divide
Recently, type Ia supernovae data appear to support a dark energy whose
equation of state crosses -1, which is a much more amazing problem than the
acceleration of the universe. We show that it is possible for the equation of
state to cross the phantom divide by a scalar field in the gravity with an
additional inverse power-law term of Ricci scalar in the Lagrangian. The
necessary and sufficient condition for a universe in which the dark energy can
cross the phantom divide is obtained. Some analytical solutions with or
are obtained. A minimal coupled scalar with different potentials,
including quadratic, cubic, quantic, exponential and logarithmic potentials are
investigated via numerical methods, respectively. All these potentials lead to
the crossing behavior. We show that it is a robust result which is hardly
dependent on the concrete form of the potential of the scalar.Comment: 11 pages, 5 figs, v3: several references added, to match the
published versio
Phantom Divide Crossing with General Non-minimal Kinetic Coupling
We propose a model of dark energy consists of a single scalar field with a
general non-minimal kinetic couplings to itself and to the curvature. We study
the cosmological dynamics of the equation of state in this setup. The coupling
terms have the form and
where
and are coupling parameters and their dimensions depend on the type
of function . We obtain the conditions required for phantom divide
crossing and show numerically that a cosmological model with general
non-minimal derivative coupling to the scalar and Ricci curvatures can realize
such a crossing.Comment: 12 pages, 4 figures. Accepted for publication in Gen. Rel. Grav.
arXiv admin note: substantial text overlap with arXiv:1105.4967,
arXiv:1201.1627, and with arXiv:astro-ph/0610092 by other author
Cosmological evolution of interacting dark energy in Lorentz violation
The cosmological evolution of an interacting scalar field model in which the
scalar field interacts with dark matter, radiation, and baryon via Lorentz
violation is investigated. We propose a model of interaction through the
effective coupling . Using dynamical system analysis, we study the
linear dynamics of an interacting model and show that the dynamics of critical
points are completely controlled by two parameters. Some results can be
mentioned as follows. Firstly, the sequence of radiation, the dark matter, and
the scalar field dark energy exist and baryons are sub dominant. Secondly, the
model also allows the possibility of having a universe in the phantom phase
with constant potential. Thirdly, the effective gravitational constant varies
with respect to time through . In particular, we consider a simple
case where has a quadratic form and has a good agreement with the
modified CDM and quintessence models. Finally, we also calculate the
first post--Newtonian parameters for our model.Comment: 14 pages, published versio
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