Glicemia e concentrações séricas de insulina, triglicérides e cortisol em equinos da raça Mangalarga Marchador após exercício físico

O presente estudo teve por objetivo avaliar a influência do exercício físico de intensidade submáxima (provas de marcha) sobre as variáveis bioquímicas sanguíneas usadas na avaliação do metabolismo energético em equinos da raça Mangalarga Marchador criados no Estado do Espírito Santo. Para tal foram obtidas amostras de soro e plasma de 15 equinos, da raça Mangalarga Marchador, em quatro momentos assim definidos: antes (T0) e com 5 minutos (T1), 30 minutos (T2) e 2 horas (T3) após o término do exercício. A análise dos resultados demonstrou a não influência do exercício físico imposto sobre a glicose plasmática, com valores médios de 117,1±35,8mg/dL, 122,6±59,6mg/dL, 124,8± 48,6mg/dL e 112,9±49,1mg/dL, e sobre a insulina sérica, com valores de mediana de 6,50mUI/mL, 2,00mUI/mL, 5,85mUI/mL e 11,60mUI/mL, respectivamente, nos tempos T0, T1, T2 e T3. De forma oposta, foi possível observar uma influência significativa sobre triglicérides séricos, com valores médios de 25,4±14,9mg/dL, 42,3±17,8mg/dL, 31,4±17,7mg/dL e 25,1±15,1mg/dL, e sobre o cortisol sérico, com valores médios de 7,46±4,37mg/dL, 12,45±3,08mg/dL, 11,40±2,52mg/dL e 6,89±1,78mg/dL, respectivamente nos tempos T0, T1, T2 e T3. A interpretação destes resultados permitiu concluir que a marcha elevou as concentrações séricas de triglicérides e cortisol. Também foi possível destacar que, por tais valores encontrarem-se dentro de intervalos fisiológicos, os equinos usados estavam aptos ao nível de exercício físico imposto na ocasião

International workshop on next generation gamma-ray source

A workshop on The Next Generation Gamma-Ray Source sponsored by the Office of Nuclear Physics at the Department of Energy, was held November 17-19, 2016 in Bethesda, Maryland. The goals of the workshop were to identify basic and applied research opportunities at the frontiers of nuclear physics that would be made possible by the beam capabilities of an advanced laser Compton beam facility. To anchor the scientific vision to realistically achievable beam specifications using proven technologies, the workshop brought together experts in the fields of electron accelerators, lasers, and optics to examine the technical options for achieving the beam specifications required by the most compelling parts of the proposed research programs. An international assembly of participants included current and prospective γ-ray beam users, accelerator and light-source physicists, and federal agency program managers. Sessions were organized to foster interactions between the beam users and facility developers, allowing for information sharing and mutual feedback between the two groups. The workshop findings and recommendations are summarized in this whitepaper

International workshop on next generation gamma-ray source

A workshop on The Next Generation Gamma-Ray Source sponsored by the Office of Nuclear Physics at the Department of Energy, was held November 17-19, 2016 in Bethesda, Maryland. The goals of the workshop were to identify basic and applied research opportunities at the frontiers of nuclear physics that would be made possible by the beam capabilities of an advanced laser Compton beam facility. To anchor the scientific vision to realistically achievable beam specifications using proven technologies, the workshop brought together experts in the fields of electron accelerators, lasers, and optics to examine the technical options for achieving the beam specifications required by the most compelling parts of the proposed research programs. An international assembly of participants included current and prospective γ-ray beam users, accelerator and light-source physicists, and federal agency program managers. Sessions were organized to foster interactions between the beam users and facility developers, allowing for information sharing and mutual feedback between the two groups. The workshop findings and recommendations are summarized in this whitepaper

Thermal conductivity, diffusivity and expansion of Avery Island salt at pressure and temperature

Preliminary data on the thermal properties of a coarse-grained rock salt from Avery Island, Louisiana, indicates that hydrostatic pressure to 50 MPa has little effect on the thermal conductivity, diffusivity and linear expansion at temperatures from 300 to 573 K. The measurements were made in a new apparatus under conditions of true hydrostatic loading. At room temperature and effective confining pressure increasing from 10 to 50 MPa, thermal conductivity and diffusivity are constant at roughly 7W/mK and 3.6 x 10/sup -6/ m/sup 2//s, respectively. At 50 MPa and temperature increasing from 300 to 573K, both conductivity and diffusivity drop by a factor of 2. Thermal linear expansion at 0 MPa matches that at 50 MPa, increasing from roughly 4.2 x 10/sup -5//K at 300 K to 5.5 x 10/sup -5/ at 573 K. The lack of a pressure effect on all three properties is confirmed by previous work. Simple models of microcracking suggest that among common geological materials the lack of pressure dependence is unique to rock salt

Clinically and temporally specific diagnostic thresholds for plasma ACTH in the horse

Objectives To derive temporally specific diagnostic thresholds for equine plasma ACTH concentration to be used alongside clinical judgement in each individual week of the year and appropriate for the degree of clinical suspicion in any given case. Furthermore, to apply these thresholds to compare the prevalence of high and low ACTH in two subgroups of animals with high and low clinical suspicion of PPID. Study design A retrospective population study examining a large laboratory database of equine plasma ACTH concentrations using an indirect approach to calculate diagnostic thresholds. Methods Logs of plasma ACTH concentrations from 75 892 individual horses were examined using robust L 2 estimation of mixtures of two normal distributions in categories of each week and month of the year. Thresholds dividing the two populations of high‐ACTH and low‐ACTH horses were then established at different levels of sensitivity and specificity and compared with clinical subgroups of horses divided based on reported clinical signs, as having high (n = 4036) or low (n = 3022) clinical suspicion of PPID. Results For most of the year there were small interweek differences in diagnostic thresholds. However, from mid‐June to early‐December diagnostic thresholds showed greater interweek variability, reaching a maximum in late September and early October. Grouping of high‐ and low‐ACTH compared favourably with grouping based on clinical signs. Main limitations Given the multiple sources of diagnostic samples, pre‐analytical data could not be fully verified. Conclusions Diagnostic thresholds for equine plasma ACTH vary through the year. It is especially important to consider the temporally specific threshold between June and December. Different clinical thresholds can be used depending on the case circumstances and whether a false‐positive or false‐negative diagnosis is deemed least desirable