Developed the Biowalk4Biofuels Anaerobic digestion plant (Biogas from Algae and Biowaste)

Developed the Biowalk4Biofuels Anaerobic digestion plant (Biogas from Algae and Biowaste). Managed of the entire construction of the plant

Database SQL/Workbench - Biowalk4Biofuels project - Plant (EU FP7 Project)

Developed a SQL Database software linked to the Biowalk4Biofuels managing labview software (EU FT7 Project

Biowalk4Biofuels FP7 annual meeting

Tour to the B4B demonstration Plant Site; Review of the technical progress made to date with comparison to the DOW, deliverables and milestones; Presentation of the first part of the Project movie

Carborane-Conjugated 2-Quinolinearcarboxamide Ligands of the Translocator Protein for Boron Neutron Capture Therapy

Potential boron neutron capture therapy (BNCT) agents have been designed on the basis of the evidence about translocator protein (TSPO) overexpression on the outer mitochondrial membrane of tumor cells. The structure of the first TSPO ligand bearing a carborane cage (compound 2d) has been modified in order to find a suitable candidate for in vivo studies. The designed compounds were synthesized and evaluated for their potential interaction with TSPO and tumor cells. In vitro biological evaluation showed in the case of fluoromethyl derivative 4b a nanomolar TSPO affinity very similar to that of 2d, a significantly lower cytotoxicity, and a slightly superior performance as boron carrier toward breast cancer cells. Moreover, compound 4b could be used as a 19F magnetic resonance imaging (MRI) agent as well as labeled with 11C or 18F to obtain positron emission tomography (PET) radiotracers in order to apply the “see and treat” strategy in BNCT