6 research outputs found
Localization of thyrotropin-releasing hormone receptor and thyrotroph embryonic factor on mouse Chromosome 15
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46999/1/335_2004_Article_BF00361398.pd
Genetic mapping of the T lymphocyte-specific transcription factor 7 gene on mouse Chromosome 11
The fibronectin receptor, alpha subunit (Itga5) maps to murine Chromosome 15, distal to D15Mit16
The γ phosphorylase kinase gene, Phkg , maps to mouse Chromosome 5 near Gus
Phosphorylase kinase is a multimeric regulatory enzyme in the glycogenolytic pathway. Interest in various types of phosphorylase kinase enzyme deficiency has focused attention on cloning and mapping the enzyme subunits. We report the mapping of the catalytic γ subunit gene, Phkg , to mouse Chromosome (Chr) 5 near β-glucuronidase ( Gus ), between alpha fetoprotein ( Afp ) and erythropoietin ( Epo ). In addition, PCR-based polymorphism assays have been developed for the human (EPO) and mouse erythropoietin genes, and a unique recombinant inbred strain distribution pattern has been defined for Epo , a distal anchor marker on mouse Chr 5.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/47007/1/335_2004_Article_BF00360562.pd