A Case of Medullary Carcinoma of the Jejunum Combined with the Intestinal Lymphangiectasia Accompanied by the Malabsorption Syndrome

Aim: to present a clinical and morphological observation of an extremely rare combination of medullary carcinoma of the jejunum and intestinal lymphangiectasia in a 33-year-old patient with clinical features of malabsorption syndrome over the 10 years.Key points. An autopsy revealed a tumor formation spreading from the wall of the jejunum to the mesentery, with metastases to the mesenteric lymph nodes. The medullary carcinoma with positive expression of СD117, DOG1, EMA, PanCK, PDL-1, vimentin, mosaic non-intense expression of CA19-9, calretinin, CD10, CDX2, CEA, MUC-5AC, SATB2, and negative reaction to ALK, CD3, CD8, CD20, CD30, CD31, CD34, CD45, CD56, chromogranin, CK7, CK20, desmin. The proliferative index was high: Ki-67 > 80 %. Moreover, during the histological examination of the intestinal wall, intestinal lymphangiectasia complicated by the malabsorption syndrome was revealed.Conclusion. The uniqueness of this clinical and morphological case is in the combination of medullary carcinoma of the jejunum metastasized to the mesenteric lymph nodes with the underlying intestinal lymphangiectasia accompanied by the development of malabsorption syndrome

Software development technology with automatic configuration to classes of image processing problems

A scheme is proposed to develop image processing and analysis software based on the generation of thesaurus tables in the interpreter's kernel. The scheme is based on the combined features of dynamic libraries and an interpreter with a set of functions for image processing. As a result, the program can be divided into two parts: the first is aimed at professional software developers, and the second at users. The interpreter is able to use extra functions of dynamic libraries. It makes it possible to change the properties of the software without compilation. On the other hand, users can change the graphical interface to improve the convenience of the workplace

Mathematical modeling of hydrodynamic processes in the liquid nucleus of an ingot

The article provides examples of physical and mathematical modeling of the process of motion of melt in the fluid nucleus of the hardening ingots of continuous casting in conductive method of electromagnetic mixing (CMEM). These models can be used while choosing rational parameters of CMEM machines and for development of continuous filling process control algorithms

Garnet-based complex substituted glass ceramic materials

В статье рассмотрен комплекс гранулированных стеклокерамических материалов на основе граната

The frequency and clinical course of retinopathy of prematurity in modern developmental care conditions as evidenced by the Moscow region perinatal center

Purpose: to determine the incidence and clinical course of retinopathy of prematurity (ROP) in modern developmental  care conditions as based by the data of a level III perinatal center.Material  and methods. A retrospective study of 920 premature infants of the ROP at-risk cohort managed by the Neonatology department of Moscow Regional Perinatal Center over the 2-year period of 2017–2018 was performed. Retinopathy  was graded and treated following the respective Federal clinical guidelines.Results. Of the 920 infants who met the screening criteria, ROP was detected in 193 (28.5 %) infants; 49 infants (7.2 %) required treatment.  Of all general somatic factors, the duration of artificial ventilation of lungs showed the strongest correlation with the frequency of development and severity of ROP.  In infants with birth weight > 1000 g, the incidence of severe forms of ROP correlated with the presence of necrotizing enterocolitis and intraventricular  hemorrhages, while in children with a lower body weight at birth no such correlation was detected. Bronchopulmonary dysplasia was not found to affect the development of ROP.  In groups of infants with birth weight of 1000–1499 g and 500–999 g, the frequency of transfusions of washed red blood cells with depleted leukocyte and thrombocyte levels was generally higher in children with ROP, both with spontaneous and induced regression, but showed no difference between the two subgroups.Conclusion. Severe somatic pathology does not always accompany the progression of ROP to the threshold stage. So, in order to optimize ROP screening, it is necessary to search for new more accurate criteria for ROP development and progression risk

Heating processes in solidification of blooms

The article gives analytical solution to the ingot solidification problem based on the “equivalent sources method”. Accuracy and correctness of the obtained final relations are proved

Identification of mathematical models at heating special steel grades in furnaces

The article gives the results of parametric identification of mathematical models of nonsymmetric heat- of metal in continuous pusher furnaces with powered hearth

Main methods of optimization of metal heating conditions

The article describes о range of problems of optimal те1аГ\. heating control. Analysis of main industrial technologies optimization methods in automobile construction and metallurgical production is conducted. The article shows effectiveness and advantages of the trunk asymptotic optimization method in solution of industrial optimization tasks

Heating of thermosensitive materials in conditions of counter-flow radiation-convectional heat exchange

In this work for the first time analytical solution of radiation-convectional heating of basic geometry bodies at counter flow heat exchange was developed