1,011 research outputs found
University as an Institute of Forming the Value- and Competence-Based Codes of New Industrialization
The objective of the article is to consider a transition to neo-industrialization through a prism of codes (genetic) of the territory, allow-ing it to participate in neo-industrialization processes, and of the institutes stimulating its process, in specific conditions of managing practice. And to define a role of universities in formation of value- and competence-based codes of neo-industrialization. The plan and methodology included: analysis of relation of values and modernization; revealing of the values being characteristic for post-industrialization; revealing of neo-industrialization codes of territory and the actors forming these codes; at last, for empirical determination of neo-industrialization codes which universities create, – the poll of students of Ural state universities. So, to reveal the main codes of neo-industrialization its features were ana-lyzed being marked out by various researchers. The analysis showed that in the basis of neo-industrial development are the technical innovations rais-ing the labor productivity; the professional specialization caused by the level of education of population; and also new forms of interaction, both among the organizations and among people in a production process, creat-ing the new and updating the existing information flows and sources of their generation. Basic codes of neo-industrialization of a territory are: in-novative codes of territory (innovative solutions); production codes (pro-duction capacities); branch codes (branch specifics); information codes (in-formation and the information technologies); social-value codes (values of the population in terms of industrial transformations); social-competence codes (knowledge, ability and skills of population as of effective produc-tive force); institutional codes of territory (legislative provision of transi-tion to new type of industrialization). Respectively, the basic actors form-ing the codes of neo-industrialization are the enterprises of real sector (car-rier of production and industrial codes), society (carrier of social codes), authorities (carrier of institutional codes). Universities act as a transformer of information, innovative and value- and competence-based codes. For defining the neo-industrialization codes, what universities form, the poll of students of Ural state universities was carried out. It showed, that, to the majority of respondents, education is not only the process of knowledge transmission promoting to find job, but also the process of studying to live in the conditions being continually changed, of forming the platform for further self-development. The most of respondents are inclined to associate universities with the in-stitute of forming the competence-based codes of neo-industrialization, but also with research and international cooperation functions. As the poll showed, in Ural universities among scientific-educational measures at least represented are the meetings with business representatives – it’s a lack of interaction with enterprises, what could increase relevance and importance of the knowledge being transmitted. In the part of mutual influence of values and modernization processes, the poll showed that by new generation prevail secular-rational values what replaced the traditional values, forging the population in its behavior and needs as well as causing the resistance to innovative transformations. By new generation prevail the values of self-expression. That’s why it can be said that young generation positively percepts indus-trial transformations, being an active cell of postindustrial society. The fact that the values of self-expression prevail, testifies an active position of students and readiness to participate in changing their life. The answers of respondents received testify that one more institute of forming the social-value codes of neo-industrialization is a family, what confirms a theory of cultural transmission. In the part of the nearest planes of students after university graduation, the poll showed that new generation possesses the positive potential of in-novative transformations and neo-industrialization on the whole. The most popular answers were “to get a job on an existing enterprise”, “to study further (magistracy / postgraduate study)”, “to create family”, “to create own business”. The results of research allow to conclude, that universities set and solve, by permanently improving themselves in ways, mechanisms and instru-ments, the double task: on the one hand, form the social competence-based codes of new industrialization furthering the forming the high-qualified work force; in the other hand, form the social value-based codes of new industrialization, such as leader qualities, patriotic qualities, re-sponsibility, general culture, what will create a neo-industrial perception of world and allow to exist in it successfully
T134 Allelic imbalance and epigenetic changes as a marker of tumor spreading into the adjacent tissue
Non-small cell lung cancer (NSCLC) is characterized by multiple genetic alterations such as loss of heterozygosity (LOH), microsatellite instability (MSI), promoter hypermethylation and changes of miRNA expression. According to a field cancerization (FC) phenomenon the adjacent histologically normal tissue plays a role in tumor progression by triggering the transformation process.The aim of the study was the analysis of genetic alterations in tumor and adjacent tissue to determine the FC size and to reveal associations with clinico-morphological features of patients.The study group included 135 patients with NSCLC. From each patient 4 FFPE samples were analyzed: tumor, adjacent normal lung tissue at 2, 5, 10cm. LOH/MSI analysis was evaluated by PCR using 7 microsatellite loci. Promoter hypermethylation in genes RASSF1A FHIT, DAPK1, CDH1, CD44, TIMP3, MGMT was investigated by methyl-sensitive PCR. The expression levels of miRNAs let-7a, miR-155, miR-205 were measured by real-time PCR.Our results demonstrated that LOH/MSI occurs only in tumor while promoter hypermethylation occurs also in adjacent tissue at 2, 5cm, but not at 10cm. The downregulation of let-7a, miR-155 in adjacent tissue is lower than in tumor. The levels of investigated miRNAs in adjacent tissue vary depending on tumor differentiation – in patients with differentiated tumors it is higher than in the group with poorly differentiated tumors.We postulate that FC size in NSCLC is at least 5cm from tumor and includes only epigenetic but not structural (LOH/MSI) alterations. The evaluation of epigenetic changes in adjacent tissue (e.g., surgical margins) can potentially be used for postsurgical prognosis
Double-spiral magnetic structure of the Fe/Cr multilayer revealed by nuclear resonance scattering
We have studied the magnetization depth profiles in a [57Fe(dFe)/Cr(dCr)]x30
multilayer with ultrathin Fe layers and nominal thickness of the chromium
spacers dCr 2.0 nm using nuclear resonance scattering of synchrotron radiation.
The presence of a broad pure-magnetic half-order (1/2) Bragg reflection has
been detected at zero external field. The joint fit of the reflectivity curves
and Mossbauer spectra of reflectivity measured near the critical angle and at
the "magnetic" peak reveals that the magnetic structure of the multilayer is
formed by two spirals, one in the odd and another one in the even iron layers,
with the opposite signs of rotation. The double-spiral structure starts from
the surface with the almost antiferromagnetic alignment of the adjacent Fe
layers. The rotation of the two spirals leads to nearly ferromagnetic alignment
of the two magnetic subsystems at some depth, where the sudden turn of the
magnetic vectors by ~180 deg (spin-flop) appears, and both spirals start to
rotate in opposite directions. The observation of this unusual double-spiral
magnetic structure suggests that the unique properties of giant
magneto-resistance devices can be further tailored using ultrathin magnetic
layers.Comment: 9 pages, 3 figure
Six-membered heterocycles - I. The stereoisomerism of 2-alkyl-5-hexyl-1,3-dioxanes
2-Methyl-5-hexyl- and 2-isopropyl-5-hexyl-1, 3-dioxanes have been synthesized for the first time by the condensation of 2-hexyl-1, 3-propane-diol with acetaldehyde and isobutyraldehyde, and they have been separated into their stereoisomers by fractionation in efficient columns. It has been shown by a study of their PMR spectra that the low-boiling isomers have the cis- and the high-boiling isomers the trans-configuration. A study of the PMR spectra has enabled us to show not only the configuration but also the predominant conformations of the isomers; the cis-isomer exists predominantly in the unsymmetrical boat conformation with a diequatorial location of the substituents and the trans-isomer in the chair conformation, also with a diequatorial arrangement of the substituents. © 1971 Consultants Bureau
Search for a signal on intermediate baryon systems formation in hadron-nuclear and nuclear-nuclear interactions at high energies
We have analyzed the behavior of different characteristics of hadron-nuclear
and nuclear-nuclear interactions as a function of centrality to get a signal on
the formation of intermediate baryon systems. We observed that the data
demonstrate the regime change and saturation. The angular distributions of slow
particles exhibit some structure in the above mentioned reactions at low
energy. We believe that the structure could be connected with the formation and
decay of the percolation cluster. With increasing the mass of colliding nuclei,
the structure starts to become weak and almost disappears ultimately. This
shows that the number of secondary internuclear interactions increases with
increasing the mass of the colliding nuclei. The latter could be a reason of
the disintegration of any intermediate formations as well as clusters, which
decrease their influence on the angular distribution of the emitted particles.Comment: 2 pages and one figur
The study of the lunar macro-figure models using multi-parametric harmonic analysis and expansion in spherical functions
© SGEM2017 All Rights Reserved. The present work is focusing on construction and analysis of 5 lunar models using space and ground observations. Firstly, it should be noted that the task of building a model of the lunar macro-figure relative to its center of mass and axes of inertia does not have a definitive solution yet. Within the present work the models of the lunar macro-figure are developed on the basis of space and ground observations. The methods of observation had implied binding of lunar objects to stars, i.e. celestial coordinate system. As observations of that kind the data from “Clementine”, “Kaguya”, “LRO” space missions, and large-scale photographs of the Moon with stars were used. 5 models were constructed using the software “Automatic System of Scientific Investigation” (ASSI). Based on the results of the work the following conclusions are drawn after the analysis of the constructed models’ cross-sections for longitudes λ = -40°, -20°, 0°, 20°, 40°: 1) The mean level of the lunar southern hemisphere is higher than the northern one; 2) The lowering for northern latitudes in the range of 30° - 45° according to the ground observations is of the same order as based on the data from the space missions. Then, however, altitudes taken from the ground observations are starting to increase up to latitudes of 70° - 80°. This leads to significant difference between the shapes of hypsometric curves. 3) The good convergence between cross-sections of the models constructed on the basis of “Clementine” space mission and “KSC-1162” (Kazan Selenocentric Catalogue) is achieved. 4) The results of comparing the relief of the lunar surface based on ground and space images of the Moon and ALSEP system are following: a) Differences in absolute values of altitude for the near northern side of the Moon in the given systems are systematic. In this regard an alternative hypothesis concerning the shape of physical surface of the near side of the Moon has been proposed; b) The results of the analysis of ALSEP experiment data do not reject the proposed new hypothesis about relief lowering of the lunar surface to the North of the parallel + 10 ° relative to the generally accepted level; c) The analysis of space missions data with elements of a spacecraft external orienteering confirms the relief lowering of the lunar surface up to 1,5 km in the area of -70° < λ < -30°, -10° < ψ < -63° relative to the generally accepted level
The method of moonquakes selenophysical parameters analysis
© SGEM2017 All Rights Reserved. The purpose of the present study is to apply the new methods of multi-parametric analysis to moonquakes. It should be noted such physical phenomena as moonquakes are some kinds of complex systems. As the works in which analysis of moonquakes observations is conducted have shown, lunar seismophysics is much more complex process than Earth’s geophysics. This is why to study the physical nature of moonquakes and their parameters it is necessary to use methods of statistical physics and robust estimates. Currently, there are some attempts to study the lunar internal structure based on moonquakes using different seismic methods, such as signal’s passage time analysis, tomography techniques, seismic interferometry waves for deep moonquakes in order to conduct backward reflection on “Apollo” mission stations. Based on simulation of tidal lunar parameters which have been improved during the recent space missions, such as GRAIL (gravity), LRO (shape), and LLR (rotation), the presence of lunar internal layer with low viscosity coinciding with the areas where deep moonquakes take place is assumed. The method of moonquakes database analyzing is developed using the author’s time series analysis introduced for the Earth’s seismics studies based on space observations. The software applications to quantitatively describe parameters of moonquakes dynamic features are developed. A theoretical model for analyzing correlation with the lunar pole dynamics is developed for deep moonquakes. The connection of lunar poles motion dynamics and their uneven rotation with seismic activity has been tested. When developing numerical algorithms and software for moonquakes time series data processing, the modern methods of non-equilibrium statistical physics allowing obtaining a set of statistical parameters and information measures to study the statistical memory effects, periodic patterns, non-stationarity and dynamic intermittency effects, alignment and/or misalignment effects, frequency-phase synchronization from time signals have been used
Scientific and educational center of space researches and technologies in Kazan federal university
© SGEM2017. All Rights Reserved. The modern major project on creation a unique, scientific, educational, and technological Center of space researches and technologies was launched on the base of Engelhardt Astronomical Observatory (EAO) of Kazan Federal University in 2008. In EAO educational activity in the fields of training and retraining of specialists is conducted; scientific and practical training courses take place on the following educational programs: space geodesy and remote sensing, astronomy, radio astronomy. It should be noted, currently, it is necessary to develop high-tech stations and observatories, provide education in the fields of space geodesy and geophysics, and popularize the space knowledge. Kazan Federal University is one of the leading centers of Russia and the world in astronomy and space geodesy in terms of both training and fundamental and applied investigations. The scientific data which had been obtained by Kazan astronomers was used in the preparation for the missions to the Moon and Mars. In Kazan the leading scientific schools in the fields of stellar atmosphere astrophysics, space geodesy, and geophysics were established. All this allowed creating the scientific center where more than 7500 students take a short educational course on space studies annually and where classes on space knowledge popularization are taught for 25000 visitors. The scientific and educational center on the base of EAO is the first in the world complex combining the operating astronomical observatory and modern planetarium. There is a metrological geophysical testing ground operating in EAO. Such an approach allows creating a professional environment for learning about the Earth and Universe and increasing the interest in both historical and modern space concepts
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