Contributions of spontaneous phase slippage to linear and non-linear conduction near the Peierls transition in thin samples of o-TaS_3

In the Peierls state very thin samples of TaS_3 (cross-section area \sim 10^{-3} mkm^2) are found to demonstrate smearing of the I-V curves near the threshold field. With approaching the Peierls transition temperature, T_P, the smearing evolves into smooth growth of conductance from zero voltage interpreted by us as the contribution of fluctuations to the non--linear conductance. We identify independently the fluctuation contribution to the linear conductance near T_P. Both linear and non-linear contributions depend on temperature with close activation energies \sim (2 - 4) x 10^3 K and apparently reveal the same process. We reject creep of the {\it continuous} charge-density waves (CDWs) as the origin of this effect and show that it is spontaneous phase slippage that results in creep of the CDW. A model is proposed accounting for both the linear and non-linear parts of the fluctuation conduction up to T_P.Comment: 6 pages, 5 Postscript figure, RevTeX, accepted for publication in PR

Rotating vortex dipoles in ferromagnets

Vortex-antivortex pairs are localized excitations and have been found to be spontaneously created in magnetic elements. In the case that the vortex and the antivortex have opposite polarities the pair has a nonzero topological charge, and it behaves as a rotating vortex dipole. We find theoretically, and confirm numerically, the form of the energy as a function of the angular momentum of the system and the associated rotation frequencies. We discuss the process of annihilation of the pair which changes the topological charge of the system by unity while its energy is monotonically decreasing. Such a change in the topological charge affects profoundly the dynamics in the magnetic system. We finally discuss the connection of our results with Bloch Points (BP) and the implications for BP dynamics.Comment: 6 pages, 2 figure

Retinoprotective Effect of 2‐Ethyl‐3‐hydroxy‐6‐methylpyridine Nicotinate

An important task of pharmacology is to find effective agents to improve retinal microcirculation and resistance to ischemia. The purpose of the study is to pharmacologically evaluate the retinoprotective effect of 2-3-hydroxy-6-methylpyridine nicotinate in a rat model of retinal ischemia-reperfusio

Classical and relativistic dynamics of supersolids: variational principle

We present a phenomenological Lagrangian and Poisson brackets for obtaining nondissipative hydrodynamic theory of supersolids. A Lagrangian is constructed on the basis of unification of the principles of non-equilibrium thermodynamics and classical field theory. The Poisson brackets, governing the dynamics of supersolids, are uniquely determined by the invariance requirement of the kinematic part of the found Lagrangian. The generalization of Lagrangian is discussed to include the dynamics of vortices. The obtained equations of motion do not account for any dynamic symmetry associated with Galilean or Lorentz invariance. They can be reduced to the original Andreev-Lifshitz equations if to require Galilean invariance. We also present a relativistic-invariant supersolid hydrodynamics, which might be useful in astrophysical applications.Comment: 22 pages, changed title and content, added reference

Pharmacokinetic studies of new antiparkinsonian drug Rapitalam

The aim of this study was to investigate the pharmacokinetic parameters of the mGluR4 receptor blocker Rapitalam on rabbits. There was developed the method of the quantitative determination of Rapitalam in the blood plasma of rabbits using high performance liquid chromatography with tandem mass spectrometric detection. The study was performed on 12 rabbits (males, weighing between 3,300 to 3,500 g). In intragastric dosing of the substance was administered using a gastric tube in the form of suspension in water 0.9 mg/ml, 9 mg/ml, and 90 mg/ml at a dose of 0.3 mg/kg, 3 mg/kg and 30 mg/kg. The main pharmacokinetic parameters of the substance was established on rabbits that allow you to optimize the future use of it's as a potential drug for the treatment of Parkinson's diseas

Periodic sequences of arbitrage: a tale of four currencies

This paper investigates arbitrage chains involving four currencies and four foreign exchange trader‐arbitrageurs. In contrast with the three‐currency case, we find that arbitrage operations when four currencies are present may appear periodic in nature, and not involve smooth convergence to a ‘balanced’ ensemble of exchange rates in which the law of one price holds. The goal of this article is to understand some interesting features of sequences of arbitrage operations, features which might well be relevant in other contexts in finance and economics