499 research outputs found

    Formation of sustained antitumor effect in mice’s liver and spleen (CBA х C57BL/6)F1 after a single intravenous injection of zymosan-treated neutrophils

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    Application of zymosan in medicine is limited because of its side effects, since the native granules of zymosan directly activate serum complement components and phagocytic cells. In this regard, it was decided at the outset (ex vivo) to incorporate the granules of zymosan in the neutrophils, and only then inject these "loaded" zymosan neutrophils into the bloodstream. Our experiments showed a total inhibition of the weight accretion of both tumor affected liver (from 5220 ± 963 to 1327 ± 219 mg) and spleen (from 328 ± 29 to 187 ± 64 mg) of mice. Thus these data showed that even on the 17th day after a single intravenous injection zymosan-treated neutrophils persist expressed manifestations of anti-tumor activity in the liver and spleen, that may be basis for using this method for antimetastatic preventive measures in liver and other localizations

    Variations of cosmic rays according to the data of interplanetary probes Zond-3 and Venus-2

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    Cosmic ray intensity variation measured by Zond 3 and Venus 2 interplanetary probe

    Capture of particles of dust by convective flow

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    Interaction of particles of dust with vortex convective flows is under theoretical consideration. It is assumed that the volume fraction of solid phase is small, variations of density due to nonuniform distribution of particles and those caused by temperature nonisothermality of medium are comparable. Equations for the description of thermal buoyancy convection of a dusty medium are developed in the framework of the generalized Boussinesq approximation taking into account finite velocity of particle sedimentation. The capture of a cloud of dust particles by a vortex convective flow is considered, general criterion for the formation of such a cloud is obtained. The peculiarities of a steady state in the form of a dust cloud and backward influence of the solid phase on the carrier flow are studied in detail for a vertical layer heated from the sidewalls. It is shown that in the case, when this backward influence is essential, a hysteresis behavior is possible. The stability analysis of the steady state is performed. It turns out that there is a narrow range of governing parameters, in which such a steady state is stable.Comment: 14 pages, 10 figures, published in Physics of Fluid

    Religious Affiliation and Socio-Cultural Image of Staff of Omsk Railway Workshops at the Turn of 19th-20th Centuries

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    The relevance of the study is determined by insufficient exploration of the problem of religious affiliation of the employees of West Siberia railway transport enterprises at the turn of 19th-20th centuries. Attention is paid to the fact that religious affiliation is a significant social and cultural characteristics, not only of the individual, but also of social and professional communities. The novelty of the study lies in attracting and analyzing the data contained in the departmental office learned of the little-known archival documents. Their analysis allows to reconstruct the religious component of the socio-cultural image and the spiritual world of the workers of large enterprises of industrial type operating on the Siberian railroad at the turn of 19th-20th centuries. According to the authors, within the labour collective of Omsk main railway workshops there was a general increase in the number of employees belonging to different religious denominations. It is proved that religious affiliation was an important factor influencing socio-cultural image of workers and employees of the largest industrial enterprises of the Siberian railway and Omsk - the main railway workshops. The data are revealed that the professional structure of the enterprise included mostly the representatives of the Christian Orthodox denomination. The authors show that religious values influenced the way of life, cultural level of development of the personality and his attitude to his production duties

    Magnetic quantum beating of gamma radiation on 181Ta Nuclei

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    A frequency-time variant of gamma resonance spectroscopy is suggested with the use of quantum interference on Mössbauer transitions induced under the conditions of gamma magnetic resonance. Calculations are performed for the 181Ta nucleus. It has been shown that the coherent dynamics of nuclear spins is essential for the formation of the time harmonics of the absorption spectrum. © 2005 Pleiades Publishing, Inc

    Analysis of vibration impact on stability of dewetting thin liquid film

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    Dynamics of a thin dewetting liquid film on a vertically oscillating substrate is considered. We assume moderate vibration frequency and large (compared to the mean film thickness) vibration amplitude. Using the lubrication approximation and the averaging method, we formulate the coupled sets of equations governing the pulsatile and the averaged fluid flows in the film, and then derive the nonlinear amplitude equation for the averaged film thickness. We show that there exists a window in the frequency-amplitude domain where the parametric and shear-flow instabilities of the pulsatile flow do not emerge. As a consequence, in this window the averaged description is reasonable and the amplitude equation holds. The linear and nonlinear analyses of the amplitude equation and the numerical computations show that such vibration stabilizes the film against dewetting and rupture.Comment: 19 pages, 11 figure

    Radio-frequency Mössbauer spectra of the "easy"-plane type magnetic system (FeBO3)

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    The theory of formation of the RF Mössbauer spectra for the "easy"-plane type magnetics (FeBO3) and for various types of RF field polarization is presented. Experiments using both linearly and circularly polarized external RF fields were carried out at different temperatures. At room temperature the experimental spectra for both cases are well described by switching hyperfine (hf) field model. At temperatures close to the Neel temperature (335 K), the spectra in the oscillating and rotating RF field were obtained and their forms are described by models of switching and rotating hf field, respectively. © 2006 Springer Science+Business Media, Inc

    On the self-excitation of vibrations of a boring bar in the process of deep boring

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    The article presents equivalent mathematical models of a boring bar designed for deep boring, in a distributed and a discrete idealizations. A mathematical model describing coupled torsional and lateral vibrations of a boring bar is constructed in the form of a set of differential equations with lagging of the cutting process dynamics. A methodology for studying stability in small of the deep boring process using a characteristic quasi-polynomial is presented. The numerical-analytical results of the studies made it possible to discern stability regions in the parameter space of the model and to obtain relations for maximal cutting depth as a function of geometrical and technological parameters (stiffness, cutting velocity, feeding etc.) of the boring bar considered. It is noted that the obtained numerical-analytical results are in good agreement with experimental data
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