2,252 research outputs found
Vegetation analysis in the Laramie Basin, Wyoming from ERTS-1 imagery
The author has identified the following significant results. The application of ERTS-1 imagery to vegetation mapping and identification was tested and confirmed by field checking. ERTS-1 imagery interpretation and density contour mapping allows definition of minute vegetation features and estimation of vegetative biomass and species composition. Large- and small-scale vegetation maps were constructed for test areas in the Laramie Basin and Laramie mountains of Wyoming. Vegetative features reflecting grazing intensity, moisture availability, changes within the growing season, cutting of hay crops, and plant community constituents in forest and grassland are discussed and illustrated. Theoretical considerations of scattering, sun angle, slope, and instrument aperture upon image and map resolution were investigated. Future suggestions for applications of ERTS-1 data to vegetative analysis are included
Assessing functional novelty of PSI structures via structure-function analysis of large and diverse superfamilies
The structural genomics initiatives have had as one of their aims to improve our understanding of protein function by providing representative structures for many structurally uncharacterised protein families. As suggested by the recent assessment of the Protein Structure Initiative (Structural Genomics Initiative, funded by the NIH), doubts have arisen as to whether Structural Genomics as initially planned were really beneficial to our understanding of biological issues, and in particular of protein function.
A few protein domain superfamilies have been shown to account for unexpectedly large numbers of proteins encoded in fully sequenced genomes. These large superfamilies are generally very diverse, spanning a wide range of functions, both in terms of molecular activities and biological processes. Some of these superfamilies, such as the Rossmann-fold P-loop nucleotide hydrolases or the TIM-barrel glycosidases, have been the subject of extensive structural studies which in turn have shed light on how evolution of the sequence and structure properties produce functional diversity amongst homologues. Recently, the Structure-Function Linkage Database (SFLD) has been setup with the aim of helping the study of structure-function correlations in such superfamilies. Since the evolutionary success of these large superfamilies suggests biological importance, several Structural Genomics Centers have focused on providing full structural coverage for representatives of all sequence families in these superfamilies.
In this work we evaluate structure/function diversity in a set of these large superfamilies and attempt to assess the quality and quantity of biological information gained from Structural Genomics.

Processing double refractory gold-arsenic-bearing concentrates by direct reductive melting
Iron arsenides may be the key to extraction of gold from existing refractory ores such as that at Bakyrchik, Kazakhstan, an ore body containing an estimated ÂŁ8.5Â billion reserve of gold. Gold is not extractable without significant ecological contamination from the associate arsenopyrite mineralisation. A new method for gold recovery from refractory gold-arsenic-bearing materials, based on direct reductive melting (DRM) of the concentrate has been developed, which locks As into relatively benign iron arsenide phases, whilst gold is extracted into lead alloy. The method has been filed as a patent with the Patent Office of the Republic of Kazakhstan.Islamic Development Bank - Cambridge International Scholarship Programm
Hoi An in the seventeenth and eighteenth centuries: an international entrepot
Master of ArtsCenter for Southeast Asian StudiesUniversity of Michiganhttps://deepblue.lib.umich.edu/bitstream/2027.42/149086/1/013852925.pd
CATHEDRAL: A Fast and Effective Algorithm to Predict Folds and Domain Boundaries from Multidomain Protein Structures
We present CATHEDRAL, an iterative protocol for determining the location of previously observed protein folds in novel multidomain protein structures. CATHEDRAL builds on the features of a fast secondary-structure–based method (using graph theory) to locate known folds within a multidomain context and a residue-based, double-dynamic programming algorithm, which is used to align members of the target fold groups against the query protein structure to identify the closest relative and assign domain boundaries. To increase the fidelity of the assignments, a support vector machine is used to provide an optimal scoring scheme. Once a domain is verified, it is excised, and the search protocol is repeated in an iterative fashion until all recognisable domains have been identified. We have performed an initial benchmark of CATHEDRAL against other publicly available structure comparison methods using a consensus dataset of domains derived from the CATH and SCOP domain classifications. CATHEDRAL shows superior performance in fold recognition and alignment accuracy when compared with many equivalent methods. If a novel multidomain structure contains a known fold, CATHEDRAL will locate it in 90% of cases, with <1% false positives. For nearly 80% of assigned domains in a manually validated test set, the boundaries were correctly delineated within a tolerance of ten residues. For the remaining cases, previously classified domains were very remotely related to the query chain so that embellishments to the core of the fold caused significant differences in domain sizes and manual refinement of the boundaries was necessary. To put this performance in context, a well-established sequence method based on hidden Markov models was only able to detect 65% of domains, with 33% of the subsequent boundaries assigned within ten residues. Since, on average, 50% of newly determined protein structures contain more than one domain unit, and typically 90% or more of these domains are already classified in CATH, CATHEDRAL will considerably facilitate the automation of protein structure classification
High Speed Phase-Resolved 2-d UBV Photometry of the Crab pulsar
We report a phase-resolved photometric and morphological analysis of UBV data
of the Crab pulsar obtained with the 2-d TRIFFID high speed optical photometer
mounted on the Russian 6m telescope. By being able to accurately isolate the
pulsar from the nebular background at an unprecedented temporal resolution (1
\mu s), the various light curve components were accurately fluxed via
phase-resolved photometry. Within the range, our datasets are consistent
with the existing trends reported elsewhere in the literature. In terms of flux
and phase duration, both the peak Full Width Half Maxima and Half Width Half
Maxima decrease as a function of photon energy. This is similarly the case for
the flux associated with the bridge of emission. Power-law fits to the various
light curve components are as follows; \alpha = 0.07 \pm 0.19 (peak 1), \alpha
= -0.06 \pm 0.19 (peak 2) and \alpha = -0.44 \pm 0.19 (bridge) - the
uncertainty here being dominated by the integrated CCD photometry used to
independently reference the TRIFFID data. Temporally, the main peaks are
coincident to \le 10 \mu s although an accurate phase lag with respect to the
radio main peak is compromised by radio timing uncertainties. The plateau on
the Crab's main peak was definitively determined to be \leq 55 \mu s in extent
and may decrease as a function of photon energy. There is no evidence for
non-stochastic activity over the light curves or within various phase regions,
nor is there evidence of anything akin to the giant pulses noted in the radio.
Finally, there is no evidence to support the existence of a reported 60 second
modulation suggested to be as a consequence of free precession.Comment: 13 pages, 12 figures, accepted for publication in Astronomy &
Astrophysic
Tissue biochemical diversity of 20 gooseberry cultivars and the effect of ethylene supplementation on postharvest life
The European gooseberry (Ribes uva-crispa) is still an understudied crop with limited data available on its biochemical profile and postharvest life. A variety of polyphenols were detected in the skin and flesh of 20 gooseberry cvs, representing mainly flavonol glycosides, anthocyanins and flavan-3-ols. In contrast, gooseberry seeds were for the first time characterised by the presence of considerable amounts of hydroxycinnamic acid glycosides tentatively identified by UPLC-QToF/MS. All cvs examined represented a good source of vitamin C while being low in sugar. Furthermore, the postharvest stability of bioactives was explored by supplementation of exogenous ethylene in air at 5 °C. Results suggest a low sensitivity of gooseberries to ethylene. The overall quality of gooseberries remained stable over two weeks, showing potential for extended bioactive life
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