Synthesis of aryl-substituted thieno[3,2-b]thiophene derivatives and their use for N,S-heterotetracene construction

Fiesselmann thiophene synthesis was applied for the convenient construction of thieno[3,2-b]thiophene derivatives. Thus, new 5- or 6-aryl-3-hydroxythieno[3,2-b]thiophene-2-carboxylates were obtained by condensation of 5- or 4-aryl-3-chlorothiophene-2-carbox-ylates, respectively, with methyl thioglycolate in the presence of potassium tert-butoxide. The saponification of the resulting esters, with decarboxylation of the intermediating acids, gave the corresponding thieno[3,2-b]thiophen-3(2H)-ones. The latter ketones were used to synthesize new N,S-heterotetracenes, namely 9H-thieno[2',3':4,5]thieno[3,2-b]indoles by their treatment with arylhydrazines in accordance with the Fischer indolization reaction. © 2019 Demina et al.; licensee Beilstein-Institut.Russian Foundation for Basic Research, RFBR: 18-33-20083This study was supported by the Russian Foundation for Basic Research, Grant No. 18-33-20083

APPLICATION OF STIRLING ENGINES TO GENERATE ELECTRICITY IN THE SECONDARY THERMAL ENERGY

This paper considers the actual problem of increasing the efficiency of energy equipment using waste energy. It is proposed to use the heat of the flue gas as a fuel for the Stirling engine. Economic efficiency of use of the Stirling engine. Economic efficiency of use of the Stirling engine calculated.В работе рассматривается актуальная проблема повышения эффективности энергетического оборудования с использованием вторичных энергоресурсов. Предлагается использовать теплоту уходящих газов как топливо для двигателя Стирлинга. Рассчитана экономическая эффективность использования двигателя Стирлинга

Synthesis, photophysical and redox properties of the 2,5,7-tri(het)aryl- [1,2,4]triazolo[1,5-a]pyrimidines

A number of Y-type push-pull compounds based on the [1,2,4]triazolo[1,5-a]pyrimidine core, namely 5,7- di(het)aryl-substituted 2-phenyl-[1,2,4]triazolo[1,5-a]pyrimidines, were obtained by transition metal free nucleophilic C-H functionalization. Substituents at both the C-5 and C-7 positions were introduced by successive treatment of the starting 6-bromo-2-phenyl-[1,2,4]triazolo[1,5-a]pyrimidine with Grignard reagents. In addition, the optical and electrochemical properties of the synthesized push-pull systems were studied. © 2020 Arkat. All rights reserved.This research study was supported financially by the Russian Science Foundation (Project No. 19-13-00234)

Microwave-Assisted synthesis and evaluation of antibacterial activity of novel 6-fluoroaryl-[1,2,4]triazolo[1,5-A]pyrimidines

A series of 6-fluoroaryl substituted [1,2,4]triazolo[1,5-A]pyrimidines have been synthesized by using the microwave-Assisted Suzuki cross-coupling reaction from readily available 6-bromo-[1,2,4]triazolo[1,5-A]pyrimidine. The antimicrobial activity of new compounds has been evaluated in vitro against Mycobacterium tuberculosis H37Rv and gram-negative (Neisseria gonorrhoeae ATCC 49226) bacteria. © ARKAT-USA, Inc

Synthesis of Regular Polyhexene in Perfluoromethylcyclohexane

This work was supported by the Russian Science Foundation (Ref. № 18-13-00365)

Benzo[ b]selenophene/thieno[3,2- b]indole-Based N,S,Se-Heteroacenes for Hole-Transporting Layers

Two series of new N,S,Se-heteroacenes, namely, 6H-benzo[4′,5′]selenopheno[2′,3′:4,5]thieno[3,2-b]indoles and 12H-benzo[4″,5″]selenopheno[2″,3″:4′,5′]thieno[2′,3′4,5]thieno[3,2-b]indoles, were successfully obtained using an effective strategy based on Fiesselmann thiophene and Fischer indole synthesis. The new molecules exhibit a large optical band gap (2.82 eV < Egopt < 3.23 eV) and their highest occupied molecular orbital (HOMO) energy formed by the plane π-core ranges between -5.2 and -5.6 eV, with the narrower optical band gap and lower HOMO level corresponding to selenated heteroacenes. In thin solid films of the heteroacenes, hole mobility measured using the conventional CELIV technique ranges between 10-5 and 10-4 cm2·V-1·s-1. All these make the proposed condensed-ring compounds a promising platform for the development of hole-transporting materials applicable in organic electronics. Copyright © 2020 American Chemical Society.The research (synthesis of new heteroacenes and investigation of their semiconductor properties) was financially supported by the Russian Science Foundation (project no. 18-13-00409). N.S.D. and N.A.R. would like to acknowledge the financial support for the analytical studies of synthesized compounds from the Ministry of Education and Science of the Russian Federation within the framework of the State Assignment for Research (project no. AAAA-A19-119012490006-1). The authors are grateful to Grigory A. Kim for carrying out the DFT calculations which were performed using ⟨⟨Uran⟩⟩ supercomputer of the Institute of Mathematic and Mechanics of the Ural Branch of the Russian Academy of Sciences. The XRD measurements were performed using the equipment of CKP FMI IPCE RAS

ОСОБЕННОСТИ ОНТОГЕНЕЗА СКЕЛЕТА ГОЛОВЫ САМЦОВ АМЕРИКАНСКОЙ НОРКИ ГЕНОТИПОВ STANDARD И LAVENDER (в норме и при воздействии препарата биостил)

The paper explores Biostil specimen on the American mink males of Standard and Lavender genotypes. The males selected were of different age from the experimental fur farm of theInstituteofCytologyand Genetics of Siberian Department ofRussianAcademyof Science. The paper is aimed at investigation of the influence on the growth and development of American mink males’ case brain skeleton of different genotypes aged 40–50; 86–90 and 176–180 days. The mink stock was bred by parents who were fed with Biostil dozed 0.05 ml/kg of body weight during 5 days before oestrum and during the oestrum. The authors observed the control animals who were not fed with Biostil. The mink stock was divided into the experimental and control groups according to the age and genotype features. The research was conducted by means of descriptive anatomic method and craniometric features. The authors found out 18 craniometric features. The research results show that Biostil influences positively morphogenesis of American mink males’ case brain of Standard genotype and some negative impact of Biostil on Lavender genotype. These impacts are mostly observed in the group of the males of reproductive age. Biostil impact on the morphogenesis of Lavender minks (a/a m/m) is followed by the changes in physiological parameters of growth and development of case brain that are mostly observed in the reproductive age. This impact is characterized by lower parameters of the case brain and lower growth of dorsal, ventral, cervical and sagittal crests.Проведены исследования препарата биостил на самцах американских норок генотипов Standard и Lavender разных возрастных групп на экспериментальной звероферме Института цитологии и генетики СО РАН. Целью работы являлось изучение влияния препарата биостил на рост и развитие скелета самцов американской норки разных окрасочных генотипов в возрасте 40–50; 86–90 и 176–180 дней на примере черепа. Поголовье норчат было получено от родительских пар, которым добавляли в корм биостил перед гоном в течение 5 дней и в период гона трёхкратно через день в дозе 0,05 мл/кг массы тела. Контролем служили животные, родители которых не получали с кормом биостил. Потомство было разделено на опытные и контрольные группы в соответствии с возрастными и генотипическими особенностями. Исследования проводили с помощью описательного анатомического метода и краниометрических измерений. Определено 18 краниометрических показателей. Результаты проведенных исследований позволяют сделать вывод о положительном влиянии препарата на морфогенез черепа самцов американской норки генотипа Standard и некотором угнетающем влиянии биостила на формирование черепа самцов американской норки генотипа Lavender. Указанные воздействия препарата наиболее выражены в группе самцов репродуктивного периода. Воздействие препарата на морфогенез черепа особей Lavender (a/a m/m) сопровождается изменением физиологических параметров роста и развития черепа, которые более четко проявляются в репродуктивном периоде и выражаются уменьшением размеров черепа, снижением активности роста дорсального, вентрального, затылочного и сагиттального гребней

THERMAL CONDUCTIVITY OF FLUORINATED SOLUTIONS OF UNSATURATED HYDROCARBONS WITH A POSITIVE EXCESS VOLUME

Solutions of perfluorinated compounds and unsaturated hydrocarbons are highly nonideal systems. A decrease in the thermal conductivity of solutions relative to their additive values in the entire concentration range and their correlation with the values of excess volumes were found.Работа выполнена при финансовой поддержке РФФИ, грант № 19-38-90075