Cichoń’s diagram for uncountable cardinals

We develop a version of Cichoń’s diagram for cardinal invariants on the generalized Cantor space 2 κ or the generalized Baire space κ κ , where κ is an uncountable regular cardinal. For strongly inaccessible κ, many of the ZFC-results about the order relationship of the cardinal invariants which hold for ω generalize; for example, we obtain a natural generalization of the Bartoszyński–Raisonnier–Stern Theorem. We also prove a number of independence results, both with < κ-support iterations and κ-support iterations and products, showing that we consistently have strict inequality between some of the cardinal invariants

High Frequency of the Apolipoprotein E*4 Allele in African Pygmies and Most of the African Populations in Sub-Saharan Africa

Apolipoprotein E genotypes (alleles *2, *3, and *4) have been determined in 70 Aka Pygmies and 470 unrelated African sub-Saharan subjects. Allele frequencies for Pygmies are 5.7% for APOE*2, 53.6% for APOE*3, and 40.7% for APOE*4, and the global proportions for sub-Saharan subjects are 11.6% for APOE*2, 70.6% for APOE*3, and 17.8% for APOE*4. The frequencies in some ethnic groups are statistically different from the overall mean in the Afar and the Isa, the Ewe (Togo), the Malinké (Guinea), and the Mossi; three ethnic groups have a higher allele frequency of APOE*4 (Fon, 29.4%; Zairians, 33.3%; Tutsi, 38.5%). The APOE*4 allele is considered the ancestral form because of its high frequency in African Pygmies and other aboriginal population