The design of systems for learning and working in librarianship.

The paper presents a philosophy and theory for the design of a system that would mediate between the librarian as a knowledge worker and the library as a learning organization. It does this by combining Activity Theory and Ecological Interface Design. The task to be supported is that of classification. The hypothesis is that the task of library classification can be supported by using the surrounding organization as an interactive learning environment, as the process of organizational learning depends on an appreciation of the cognitive process of classification

Oscillatory subglacial drainage in the absence of surface melt

The presence of strong diurnal cycling in basal water pressure records obtained during the melt season is well established for many glaciers. The behaviour of the drainage system outside the melt season is less well understood. Here we present borehole observations from a surge-type valley glacier in the St Elias Mountains, Yukon Territory, Canada. Our data indicate the onset of strongly correlated multi-day oscillations in water pressure in multiple boreholes straddling a main drainage axis, starting several weeks after the disappearance of a dominant diurnal mode in August 2011 and persisting until at least January 2012, when multiple data loggers suffered power failure. Jökulhlaups provide a template for understanding spontaneous water pressure oscillations not driven by external supply variability. Using a subglacial drainage model, we show that water pressure oscillations can also be driven on a much smaller scale by the interaction between conduit growth and distributed water storage in smaller water pockets, basal crevasses and moulins, and that oscillations can be triggered when water supply drops below a critical value. We suggest this in combination with a steady background supply of water from ground water or englacial drainage as a possible explanation for the observed wintertime pressure oscillations

Washington University Record, March 28, 2003

https://digitalcommons.wustl.edu/record/1962/thumbnail.jp

Design and Optimization of Mefenamic acid Fast Dissolving Tablets Employing Modified Starch by 23 Factorial Design

Latest developments in the technology have promoted viable dosage alternatives through oral route for pediatrics, bed ridden, and nauseous patients. Patient preference is one of the most important aspects in pharmacy practice. Now a day’s pharmacy companies are coming up with innovative drug delivery systems to deliver the drugs efficiently and with less side effects. This innovation led to the introduction of the concept of fast dissolving tablets. Though, a wide range of superdisintegrant is available for formulation of fast dissolving tablets. Still there is continuous need of development of superdisintegrants. Therefore in the present investigation, starch based superdisintegrant was prepared and evaluated for its application in the design of fast dissolving dosage forms. Keywords: Fast Dissolving Tablets, Superdisintegrant, Modified Starch, Mefenamic acid

Design, Optimization and Evaluation of Piroxicam Fast Dissolving Tablets Employing Modified Starch by 23 Factorial Design.

Fast dissolving tablet have potential advantages over conventional dosage forms, which has helped patient compliance, convenience, bioavailability and rapid onset of action. These are very good for drug delivery over geriatric and pediatric patients. They have significant advantages of solid and liquid dosage forms, because when they are in solid form and when transformed into liquid form and within few seconds after it is consumed. With new technologies for it formulation many commercial products are available in the market for the patients. So FDT have awful scope for being the delivery system. Therefore in the present investigation, starch based superdisintegrant was prepared and evaluated for its application in the design of fast dissolving dosage forms of piroxicam. Keywords: Fast Dissolving Tablets, Superdisintegrant, Modified Starch, Piroxicam

Taste masking Technologies: A Boon for Oral Administration of Drugs

Oral administration is widely used route of administration of drugs. The drug travels from the mouth, into the esophagus, then into the intestines. Sensing the taste is the major function of the tongue. In the formulation for pediatric & geriatric, bedridden & non-Cooperative patients, the main challenge to compounding pharmacist is to mask the taste of obnoxious and bitter drugs, result in patient non-compliance. Patients now expect and demand formulations that are pleasantly, or at least tolerable, flavored. This article reviews on taste-masking technologies and approaches for taste masking and bitterness reduction of dosage forms.  Keywords: Oral Administration, Drugs, Taste making, Taste bu

Open Economies and Patterns of Trade

This chapter takes up the relationship between foreign trade and growth in developing countries in the latter part of the twentieth century. Regional diversity was again the rule, with changing patterns of trade accompanying structural transformation. Fast-growing regions generally recorded increases in shares of manufactured exports with mid and high technological content, the most impressive being the Tigers and, in its speed of transformation, China. Recently in some countries, economic growth has been associated with specialization in dynamic services such as information and communications technologies, with India standing out in this regard. In the slow-growing regions on the other hand, trade diversification and technological upgrading were far less evident. The slow growers were also subject to terms-of-trade and other external shocks

Growth and Sectoral Policy

Policies regarding growth and sectoral strategies to support long-term structural transformation are the focus of this chapter. A theory of growth for a developing economy is the first topic. It serves as the background for analyzing policy frameworks for industry and agriculture and their interactions with trade

Financial Structures

The financial side of an economy undergoes structural change through the development process. There is no strict progression of financial development and initial conditions matter. But, broadly speaking, new financial structures gradually evolve, in a process that can be seen as a sequence of five "stages" of increasing financial complexity. Understanding financial structures is crucial for the analysis of macroeconomic policy in Chapter 7, since they can increase policy flexibility but can also constrain policy maneuver and generate risks of destabilization for the entire macroeconomy