Efficient Real Time Vehicles Detection Approach for Complex Urban Traffic Management

Vehicles now a day are becoming very necessary part of our life this is leading to increase in congested traffic conditions around the world. With our research in this domain of vehicle detection with image processing we are focusing on detection of vehicles. This is then combined with car size detection. Our approach is to first work on the feature of four wheeler i.e., windshield of the car. Then to work with saliency generation of the region of interest which will be containing only windshield part for the vehicles in the frame. With conversion of this frame into HSV color model. From HSV the saturation value within certain limit is kept for the segmentation then on from that leading to the detection of the vehicles in the given frame. Vehicle size detection we have considered eagle eye view for taking out area and on the basis of that deciding threshold for the vehicles into different categories. Categories of vehicles include small, medium, large vehicles for four wheelers

An Approach of Initiating Geriatric Screening OPD at the Rural Health Training Centre of SMVMCH, Pondicherry

Objectives: To study the common chronic health problems among the elderly patients attending in recently initiated geriatric screening OPD at the RHTC. Material and Methods: Since one year, screening OPD has been started at RHTC of SMVMCH, for old patients (>60 years), twice a week. A team of trained medical interns, a post-graduate, a faculty in Community Medicine and a counselor screen and counsel the elderly patients for common medical and mental health problems. The screening tool is structured and has been adopted for patients of geriatric OPD at RHTC. The screening tool consist of General Health Questionnaire (GHQ-5), Psychosis screening, Alzheimer’s disease (AD8) questionnaire and checklist of common medical conditions. Patients were screened for early detection of health problems followed by counseling them/their caregivers and referral to specialty OPD for further care. Results: Total 512 elderly patients were screened over 4 months period from the start of geriatric OPD. Out of them, 276 (54%) and 117 (23%) were between the age group of 60-65 years and 66-70 years respectively. Among them 387 (75%) were below poverty line and 68 (13.3%) were having some kind of health insurance. GHQ score indicates that 255 (50%) patients had a score more than one and it was significantly higher among females compared to males. About 76 (16.8%) elderly had a score of > 1 for psychosis, out of which only 12 (14%) were referred to the higher centre. AD8 score shows 204 (40%) patients attended the clinic having a score more than 1 and it is significantly higher among females compared to males. Counseling for caregivers was given only in 13 (6%) of the patients with high AD8 score. Common chronic conditions present among them were joint pains (310, 60%), visual disturbances (247, 48%), hearing difficulty (120, 23.4%) and hypertension (107, 21%). Conclusion: The proportion of people with AD8 score more than 1 is high and most common chronic condition seen is joint pain. The action component of the clinic such as referral of dementia patients, psychosis patients and counseling of their care-givers need to be strengthened

First characterization of a superconducting filter-bank spectrometer for hyper-spectral microwave atmospheric sounding with transition edge sensor readout

We describe the design, fabrication, integration and characterization of a prototype superconducting filter bank with transition edge sensor readout designed to explore millimetre-wave detection at frequencies in the range 40 to 65 GHz. Results indicate highly uniform filter channel placement in frequency and high overall detection efficiency. The route to a full atmospheric sounding instrument in this frequency range is discussed.Centre for Earth Observing Instrumentation UK (CEOI

Present status and future prospects of Gir cow

Gir cattle in Saurashtra provide milk, manure and draught power. Animal genetic resources of native breeds are largely underutilized in India and indiscriminate crossbreeding has degraded large numbers of local breeds. This is also true with Gir cattle in its native breeding tract. (i) About two-third population is either graded Gir or Gir like and hence not pure Gir, (ii) only one-third population i.e. 7.6 lakh could be 95% towards pure Gir. Hence, it is difficult to obtain large number of pure Gir animals. Since 2003–04 to 2012– 13, contribution of Saurashtra to state total indigenous cattle milk yield is 60%. A 25 years data analysis on Gir cows at CBF revealed average lactation yield as 2029 litre in 321 days lactation length and 1843.8 litre milk yield in 300 days. Production performance of Gir cows in three districts:(1) Junagadh (2) Rajkot and (3) Bhavnagar showed that average test day milk yield in Gir cows over a lactation were 7.99±0.05 litre/d for Junagadh, 6.43±0.03 litre/d for Rajkot and 6.71±0.04 litre /d for Bhavnagar district, projected values for 300-days milk yield being was 2397, 1929, and 2013 litre for the three districts respectively. Average AFC in Gir cattle of the station herd was 1527.7±14.1 days (51 mth) whereas survey study in Junagadh, Rajkot and Bhavnagar districts indicated AFC in field Gir cows as 45, 49, and 46 month, respectively. Parity had a significant effect on total lactation milk yield in Gir cows at CBF. Highest total lactation yield was observed in 2nd lactation (2132±123.4 litre) while lowest was observed in 10th lactation (1456.8±219.1 litre). Milk production traits LY and 300-d LY exhibited 10 to 13 % genetic variability in the herd. This suggests that to increase variability in the herd, genetic material from outside herd needs to be introduced

Radiation responses of 2D and 3D glioblastoma cells: a novel, 3D-specific radioprotective role of VEGF/Akt signaling through functional activation of NHEJ

Glioblastoma is resistant to conventional treatments and has dismal prognosis. Despite promising in vitro data, molecular targeted agents have failed to improve outcomes in patients, indicating that conventional two-dimensional (2D) in vitro models of GBM do not recapitulate the clinical scenario. Responses of primary glioblastoma stem-like cells (GSC) to radiation in combination with EGFR, VEGF and Akt inhibition were investigated in conventional 2D cultures and a 3-dimensional (3D) in vitro model of GBM that recapitulates key GBM clinical features. VEGF deprivation had no effect on radiation responses of 2D GSC but enhanced radiosensitivity of GSC cultures in 3D. The opposite effects were observed for EGFR inhibition. Detailed analysis of VEGF and EGF signalling demonstrated a radioprotective role of Akt that correlates with VEGF in 3D and with EGFR in 2D. In all cases, positive correlations were observed between increased radiosensitivity, markers of unrepaired DNA damage and persistent phospho-DNA-PK nuclear foci. Conversely, increased numbers of Rad51 foci were observed in radioresistant populations, indicating a novel role for VEGF/Akt signalling in influencing radiosensitivity by regulating the balance between non-homologous end-joining and homologous recombination mediated DNA repair. Differential activation of tyrosine kinase receptors in 2D and 3D models of GBM explains the well documented discrepancy between pre-clinical and clinical effects of EGFR inhibitors. Data obtained from our 3D model identify novel determinants and mechanisms of DNA repair and radiosensitivity in GBM, and confirm Akt as a promising therapeutic target in this cancer of unmet need

PATRIC: The VBI PathoSystems Resource Integration Center

The PathoSystems Resource Integration Center (PATRIC) is one of eight Bioinformatics Resource Centers (BRCs) funded by the National Institute of Allergy and Infection Diseases (NIAID) to create a data and analysis resource for selected NIAID priority pathogens, specifically proteobacteria of the genera Brucella, Rickettsia and Coxiella, and corona-, calici- and lyssaviruses and viruses associated with hepatitis A and E. The goal of the project is to provide a comprehensive bioinformatics resource for these pathogens, including consistently annotated genome, proteome and metabolic pathway data to facilitate research into counter-measures, including drugs, vaccines and diagnostics. The project's curation strategy has three prongs: ‘breadth first’ beginning with whole-genome and proteome curation using standardized protocols, a ‘targeted’ approach addressing the specific needs of researchers and an integrative strategy to leverage high-throughput experimental data (e.g. microarrays, proteomics) and literature. The PATRIC infrastructure consists of a relational database, analytical pipelines and a website which supports browsing, querying, data visualization and the ability to download raw and curated data in standard formats. At present, the site warehouses complete sequences for 17 bacterial and 332 viral genomes. The PATRIC website () will continually grow with the addition of data, analysis and functionality over the course of the project