Post-transcriptional control during chronic inflammation and cancer: a focus on AU-rich elements

A considerable number of genes that code for AU-rich mRNAs including cytokines, growth factors, transcriptional factors, and certain receptors are involved in both chronic inflammation and cancer. Overexpression of these genes is affected by aberrations or by prolonged activation of several signaling pathways. AU-rich elements (ARE) are important cis-acting short sequences in the 3′UTR that mediate recognition of an array of RNA-binding proteins and affect mRNA stability and translation. This review addresses the cellular and molecular mechanisms that are common between inflammation and cancer and that also govern ARE-mediated post-transcriptional control. The first part examines the role of the ARE-genes in inflammation and cancer and sequence characteristics of AU-rich elements. The second part addresses the common signaling pathways in inflammation and cancer that regulate the ARE-mediated pathways and how their deregulations affect ARE-gene regulation and disease outcome

Measured and calculated data belonging to paper "can calorimetry be used to measure the melting rate of deicers?"

This dataset provides the measured data from the ice melting rate tests for each tested chemical at every timestep of 0.4 seconds. The headers are the same as used as in the paper and form the measured input data of the model presented in the paper. The outcome of the model is presented for each time step in a separate file.THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND ACCESS THE FILES IN THIS DATASET CLICK ON THE DOI-LINK ABOV

Measured and calculated data belonging to paper "can calorimetry be used to measure the melting rate of deicers?"

This dataset provides the measured data from the ice melting rate tests for each tested chemical at every timestep of 0.4 seconds. The headers are the same as used as in the paper and form the measured input data of the model presented in the paper. The outcome of the model is presented for each time step in a separate file.THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND ACCESS THE FILES IN THIS DATASET CLICK ON THE DOI-LINK ABOV

ESTIMATING THE 95 th PERCENTILE OF THE PASTEVOID SPACING DISTRIBUTION IN HARDENED

The spacing equations of Powers, Philleo, and Pleau and Pigeon are used to estimate the uniform thickness of paste surrounding entrained air voids that is required to encompass 95 % of the air-paste system. Spacing equation accuracy is determined by comparison to the numerically exact result of Lu and Torquato. The air void system is approximated by spheres with radii from a lognormal distribution. For the systems studied here, both the Philleo and the Pleau and Pigeon equations are accurate to within approximately 10 %. The Powers spacing factor can be used to estimate the same quantity to within a factor of two, and could be made far more accurate by adjusting the result using the variance in the air void radius distribution

Public Sharing File System Using Google Drive

Peer-to-peer computing popularly known as P2P, is the sharing of computer resources and services by direct exchange of files between systems. We are proposing a new architecture which overcomes the disadvantages of the existing file sharing systems like DC, Torrent and so on. The proposed system tries to minimize resource consumption at the user’s side in terms of bandwidth and storage. This paper suggests an approach that improves the limitations of the traditional file sharing approach, it shows us the need of a new system and the risks attached with its implementation. DOI: 10.17762/ijritcc2321-8169.150314

Sulfur K-Edge XAS Study of Sulfidic Crosslinks in Vulcanised Rubbers

This feasibility study allowed us to establish three main results : (i) With high quality XANES spectra, it becomes quite possible to resolve the characteristic σ*(S-S), π*(S-S) and σ*(S-C) resonances; (ii) The "undulator gap scan" technique can yield excellent EXAFS spectra at the sulfur K-edge over more than 1300 eV; (iii) S K-edge EXAFS spectra made it possible to discriminate between vulcanizates with variable amounts of sulfur crosslinks and zinc sulfide