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Negative regulation of the SH2-homology-containing protein-tyrosine phosphatase-1 (Shp-1) P2 promoter by the HTLV-1 tax oncoprotein
Posttraumatic Stress Disorder Symptoms Contribute to Staff Perceived Irritability, Anger, and Aggression After TBI in a Longitudinal Veteran Cohort: A VA TBI Model Systems Study
Objective
To examine the relationship between staff perceived irritability, anger, and aggression and posttraumatic stress disorder (PTSD) in veterans with traumatic brain injury (TBI) of all severity levels.
Design
Longitudinal cohort design.
Setting
Veterans Affairs Polytrauma Transitional Rehabilitation Programs.
Participants
Veterans and service members with TBI of all severity levels enrolled in the Veterans Affairs Polytrauma Rehabilitation Centers’ Traumatic Brain Injury Model System national database (N=240).
Interventions
Not applicable.
Main Outcome Measure
Univariable and multivariable logistic regression modeling was used to examine the association between irritability, anger, and aggression and potential risk factors, including PTSD symptoms. Irritability, anger, and aggression was measured as a single construct using an item from the Mayo-Portland Adaptability Inventory-4 that was rated by program staff at admission and discharge from the inpatient rehabilitation program. PTSD symptoms were assessed using the PTSD Checklist–Civilian Version.
Results
PTSD symptoms uniquely predicted program staff-rated irritability, anger, and aggression at discharge even after controlling for severity of TBI, age, male sex, education, and annual earnings. The model explained 19% of the variance in irritability, anger, and aggression.
Conclusions
When TBI severity and PTSD symptoms were considered simultaneously in a sample of veterans, only PTSD symptoms predicted staff-rated irritability, anger, and aggression. Given the negative outcomes linked with irritability, anger, and aggression, veterans may benefit from assessment and treatment of PTSD symptoms within rehabilitation settings
Design Study of CANGAROO-III, Stereoscopic Imaging Atmospheric Cherenkov Telescopes for sub-TeV Gamma-ray
CANGAROO-III is an Imaging Atmospheric Cherenkov Telescope (IACT) array of
four 10 m telescopes for very high energy (sub-TeV) gamma-ray astronomy. A
design study of the CANGAROO-III telescope system was carried out using the
Monte Carlo technique in order to optimize the pixel size and the telescope
spacing. Studies were also made of observations at low elevation angles.Comment: 17pages, 13 figures, elsart, to appear in Astro. Part. Phy
Search for TeV gamma-rays from SN 1987A in 2001
We searched for TeV gamma-rays from the remnant of SN 1987A around 5400 days
after the supernova. The observations were carried out in 2001, from November
16 to December 11, using the CANGAROO-II Imaging Atmospheric Cherenkov
Telescope. In total, 708 minutes of ON- and 1019 minutes of OFF-source data
were obtained under good conditions. The detection threshold was estimated to
be 1 TeV, due to the mean zenith angle of 39. The upper limits for the
gamma-ray flux were obtained and compared with the previous observations and
theoretical models. The observations indicate that the gamma-ray luminosity is
lower than erg s at TeV.Comment: 8 pages, 3 figures, submitted for publication, style file adde
In vitro analysis of durability of S-PRG filler-containing composite crowns for primary molar restoration
Objective: To evaluate the reliability, maximum principal stress, shear stress, and crack initiation of a computer-aided design/computer-aided manufacturing (CAD/CAM) resin composite (RC) incorporating surface pre-reacted glass (S-PRG) filler for primary molar teeth. Methods: Mandibular primary molar crowns fabricated by experimental (EB) or commercially available CAD/CAM RCs (HC) were prepared and cemented to a resinous abutment tooth using an adhesive resin cement (Cem) or a conventional glass-ionomer cement (CX). These specimens were subjected to a single compressive test (n = 5/each) and the step-stress accelerated life testing (SSALT) (n = 12/each). Data was evaluated using Weibull analyses and reliability was calculated. Afterwards, the maximum principal stress and crack initiation point of each crown was analyzed by finite element analysis. To evaluate bonding of EB and HC to dentin, microtensile bond strength (μTBS) testing was conducted using primary molar teeth (n = 10/each). Results: There was no significant difference between the fracture loads of EB and HC for either cement (p > 0.05). The fracture loads of EB-CX and HC-CX were significantly lower than EB-Cem and HC-Cem (p 0.05). Significance: The crowns fabricated with the experimental CAD/CAM RC incorporating S-PRG filler yielded greater fracture loads and reliability than the crowns manufactured with commercially available CAD/CAM RC regardless of the luting materials. These findings suggest that the experimental CAD/CAM RC crown may be clinically useful for the restoration of primary molars.Nakase Y., Yamaguchi S., Jalkh E.B.B., et al. In vitro analysis of durability of S-PRG filler-containing composite crowns for primary molar restoration. Dental Materials 39, 640 (2023); https://doi.org/10.1016/j.dental.2023.04.006
Detection of diffuse TeV gamma-ray emission from the nearby starburst galaxy NGC 253
We report the TeV gamma-ray observations of the nearby normal spiral galaxy
NGC 253. At a distance of 2.5 Mpc, NGC 253 is one of the nearest
starburst galaxies. This relative closeness, coupled with the high star
formation rate in the galaxy, make it a good candidate TeV gamma-ray source.
Observations were carried out in 2000 and 2001 with the CANGAROO-II 10 m
imaging atmospheric Cerenkov telescope. TeV gamma-ray emission is detected at
the level with a flux of at energies 0.5 TeV. The data indicate that the
emission region is broader than the point spread function of our telescope.Comment: 4 pages, double colomn, 3 figures, aa.cl
Detection of Gamma-rays around 1TeV from RX J0852.0-4622 by CANGAROO-II
We have detected gamma-ray emission at the 6sigma level at energies greater
than 500GeV from the supernova remnant RX J0852.0-4622 (G266.2-1.2) using the
CANGAROO-II Imaging Atmospheric Cherenkov Telescope (IACT). The flux was 0.12
times of that of Crab at 1TeV. The signal centroid is consistent with the peak
of the X-ray emission in the north-west rim of the remnant.Comment: 12pages, 4figures, to be published in ApJ
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