Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic

This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic

Methods in soil protection used in Poland, Slovakia, the Czech Republic and Hungary

Soil occupies a key position within ecosystems and fulfils a number of functions, of which the ecological soil functions are of outstanding importance. Pollutants discharged into soils can have a lasting effect on these soil functions. In order to protect the soil against pollutants, on the one hand its ability to function must be secured in the long term by means of an effective avoidance of pollutant discharges. This is the subject of precautionary soil conservation. On the other hand, in the case of existing changes to the soil, it is essential for an estimate of the potential risks they pose to the environment to be made and for steps to be taken where appropriate. This report is an overview of methods currently applied in soil conservation in the Czech Republic, Poland, Slovakia and Hungary in comparison to German and international standards. This exchange of information is an important prerequisite for future joint projects and is a contribution to harmonising and standardising the methods of large-scale soil conservation in Central and Eastern Europe. (orig./SR)SIGLEAvailable from FIZ Karlsruhe / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekBundesministerium fuer Umwelt, Naturschutz und Reaktorsicherheit, Bonn (Germany)DEGerman

Silent embolic infarcts on computed tomographybrain scans and risk of ipsilateral hemisphericevents in patients with asymptomatic internalcarotid artery stenosis

Objectives: This study tested the hypothesis that silent embolic infarcts on computed tomography (CT) brain scans can predict ipsilateral neurologic hemispheric events and stroke in patients with asymptomatic internal carotid artery stenosis. Methods: In a prospective multicenter natural history study, 821 patients with asymptomatic carotid stenosis graded with duplex scanning who had CT brain scans were monitored every 6 months for a maximum of 8 years. Duplex scans were reported centrally, and stenosis was expressed as a percentage in relation to the normal distal internal carotid criteria used by the North American Symptomatic Carotid Endarterectomy Trialists. CT brain scans were reported centrally by a neuroradiologist. In 146 patients (17.8%), 8 large cortical, 15 small cortical, 72 discrete subcortical, and 51 basal ganglia ipsilateral infarcts were present; these were considered likely to be embolic and were classified as such. Other infarct types, lacunes (n = 15), watershed (n = 9), and the presence of diffuse white matter changes (n = 95) were not considered to be embolic. Results: During a mean follow-up of 44.6 months (range, 6 months-8 years), 102 ipsilateral hemispheric neurologic events (amaurosis fugax in 16, 38 transient ischemic attacks [TIAs], and 47 strokes) occurred, 138 patients died, and 24 were lost to follow-up. In 462 patients with 60% to 99% stenosis, the cumulative event-free rate at 8 years was 0.81 (2.4% annual event rate) when embolic infarcts were absent and 0.63 (4.6% annual event rate) when present (log-rank P = .032). In 359 patients with <60% stenosis, embolic infarcts were not associated with increased risk (log-rank P = .65). In patients with 60% to 99% stenosis, the cumulative stroke-free rate was 0.92 (1.0% annual stroke rate) when embolic infarcts were absent and 0.71 (3.6% annual stroke rate) when present (log-rank P = .002). In the subgroup of 216 with moderate 60% to 79% stenosis, the cumulative TIA or stroke-free rate in the absence and presence of embolic infarcts was 0.90 (1.3% annual rate) and 0.65 (4.4% annual rate), respectively (log-rank P = .005). Conclusion: The presence of silent embolic infarcts can identify a high-risk group for ipsilateral hemispheric neurologic events and stroke and may prove useful in the management of patients with moderate asymptomatic carotid stenosis

Velocity correlations of intermediate mass fragments produced in central collisions of Au + Au at E = 150 A.MeV

Velocity correlations of intermediate mass fragments (IMFs), produced in central collisions of Au + Au at 150 A.MeV beam energy, are extracted from measurements with the FOPI (phase I) detector system at SIS in GSI Darmstadt. The IMF correlation function for semicentral events is found to be affected by the directed sideward flow. When rotating the events into a unique reaction plane an enhancement of correlations, resulting from event mixing effects, vanishes. Selecting violent collisions with a high degree of azimuthal symmetry the correlation function appears nearly independent of additional event or single particle gate conditions. The comparison of the data with a Coulomb dominated final-state interaction model points to time scales of #tau# #propor to# 25 fm/c or less for emitting IMFs from an expanding and multifragmenting source with radius R #propor to# 14 fm. (orig.)SIGLEAvailable from TIB Hannover: RR 1847(93-14) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman

Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Disease Study 2019

10.1016/s0140-6736(21)01169-7The Lancet397102922337-236