1,939 research outputs found
Radiation from a Charge Uniformly Accelerated for All Time
A recent paper of Singal [Gen. Rel. Grav. 27 (1995), 953-967] argues that a
uniformly accelerated particle does not radiate, in contradiction to the
consensus of the research literature over the past 30 years. This note points
out some questionable aspects of Singal's argument and shows how similar
calculations can lead to the opposite conclusion.Comment: LaTeX, 9 pages, to appear in General Relativity and Gravitatio
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Expression and Action of Kit Ligand/Stem Cell Factor in Normal Human and Bovine Ovarian Surface Epithelium and Ovarian Cancer
Greater than 95% of ovarian cancers originate from the epithelial cells on the surface of the ovary termed ovarian surface epithelium (OSE). A normal aspect of OSE function is repeated proliferation after ovulation, and this is postulated to be involved in part in the onset of ovarian cancer. The hypothesis tested is that locally produced growth factors have an important role in controlling OSE proliferation. The current study investigates the potential role of the growth factor kit ligand (KL)/stem cell growth factor and its receptor c-kit in normal OSE biology and ovarian cancer. Human tumors from borderline, stage I, and stage III cases of ovarian cancer were found to express KL and c-kit protein in the epithelial cell component by ICC analysis. The stromal cell component of human ovarian tumors contained little immunostaining. Bovine ovarian physiology and endocrinology are similar to the human such that cow ovaries were used as a model system to investigate normal OSE functions. KL and c-kit proteins were detected in the OSE from both normal human and bovine ovaries. Adjacent ovarian stromal tissue contained less intense but positive KL and c-kit immunostaining. To extend the ICC results, RNA was collected from normal bovine OSE and ovarian stromal cells to examine KL gene expression. KL transcripts were detected in cultured OSE and stromal cells by Northern blot analysis. KL gene expression was found to be high in freshly isolated OSE but low in freshly isolated stroma using a quantitative polymerase chain reaction procedure. Levels of KL gene expression in cultured OSE and stroma increased to high levels. Observations indicate that normal OSE expresses high levels of KL in vivo and in vitro. The actions of KL on the growth of both normal OSE cells and ovarian cancer cells was investigated. KL was found to stimulate the growth of normal OSE cells in a similar manner to epidermal growth factor. Observations demonstrate the production and action of KL by normal OSE cells and ovarian cancer cells. Coexpression of KL and c-kit by normal OSE suggests that KL can act as an autocrine factor for OSE. The local production and action of KL on OSE provides insight into normal OSE biology, and a factor that may be involved in the onset and progression of ovarian cancer
A Collaborative, Trilateral Approach to Bridging the Information Literacy Gap in Student Writing
As localized assessments confirm national findings that undergraduates struggle to integrate resources into research-based compositions effectively, data at one comprehensive public university indicate library sessions improve students’ ability to locate and evaluate information, but students continue to struggle with the “use” component of information literacy. This article presents a trilateral case study among librarians, faculty, and writing center administrators, emphasizing the intersection of programmatic partnerships, assessment, and pedagogical best practices. Our research shows a trilateral approach to information literacy increases efficacy and a sense of shared responsibility in support of student research where traditional bilateral approaches fall short
THYMUS-DEPENDENT AREAS IN THE LYMPHOID ORGANS OF NEONATALLY THYMECTOMIZED MICE
Specific areas of lymphocyte depletion, termed thymus-dependent areas, have been delineated in neonatally thymectomized C3H/Bi and F1 (C57BL x C3H/Bi) mice. They occur within the lymphoid follicles of the spleen immediately surrounding the central arterioles, and constitute the mid and deep cortical zones of the lymph nodes. These depleted areas appear in healthy thymectomized mice as early as 3 wk after operation but, in mice which survive for more than 6 to 7 wk, the thymus-dependent areas are repopulated by rapidly dividing pyroninophilic cells, the majority of which are immature plasma cells. Syngeneic thymus cells, labeled in vitro with tritiated adenosine localize preferentially in the thymus-dependent areas after intravenous injection. Similarly labeled spleen cells also accumulate in these areas but, in addition, are distributed at the periphery of splenic follicles and in the outer cortical zone of the lymph nodes. Many more spleen than thymus cells enter the lymphoid tissues and the spleen appears to be the primary target. The apparent paradox that syngeneic thymus cells are less efficient than spleen cells in restoring neonatally thymectomized mice to normality is discussed in the light of these results and possible routes by which the migrating cells could enter the lymphoid tissues are considered. The origin of the plasma cells which repopulate the lymphocyte depleted areas is also discussed. It is concluded that the normal thymus produces cells which contribute directly to the migratory or circulatory lymphocyte population but that there also exists another source of supply for the plasma cell series. These two systems may function synergistically so that the thymus may control, directly or indirectly, the balance of cell populations within the body
Lattice thermal conductivity of freestanding gallium nitride nanowires
aip Publishers Publications Topics | Librarians Authors Your access is provided by: Eastern Illinois University Register to create your user account, or sign in if you have an existing account Additional sign in Sign in via Shibboleth/Athens My cart Export citations Add to my favorites Recommend to library Subscribe to email alerts Submit an article Reprints & Permissions Subscribe to RSS Access Key Free Content Open Access Content Subscribed Content Free Trial Content Home \u3e Publishers \u3e AIP Publishing \u3e Journal of Applied Physics \u3e Volume 108, Issue 3 \u3e Article banner image F Lattice thermal conductivity of freestanding gallium nitride nanowires Download PDF Jie Zou1,a) + View Affiliations a) Electronic mail: [email protected]. J. Appl. Phys. 108, 034324 (2010); http://dx.doi.org/10.1063/1.3463358 Previous Article Table of Contents Next Article Back to Search Results facebook twitter Share this page separator email print this page Abstract Full Text References (28) Cited By (8) Data & Media Metrics Related We report detailed calculations of the lattice thermal conductivity of freestanding gallium nitride(GaN)nanowires with diameters ranging from 20 to 140 nm. Results are compared with experimental data on GaNnanowires grown by thermal chemical vapor deposition(CVD). Calculations are based on the Boltzmann transport equation and take into account the change in the nonequilibrium phonon distribution in the case of diffuse scattering at the surfaces. Phonon dispersion relation is obtained in the elastic continuum approximation for each given nanowire. For valid comparisons with the experimental data, simulations are performed with a dopant concentration and impurity profile characteristic of thermal CVDGaNnanowires. Our results show that the room-temperature thermal conductivity of the nanowires has very low values, ranging from 6.74 W/m K at 20 nm to 16.4 W/m K at 140 nm. The obtained results are in excellent agreement with the experimental data. We have also demonstrated that in addition to impurity scattering, boundary scattering, and phonon confinement, the change in the nonequilibrium phonon distribution leads to a further reduction in the thermal conductivity of the nanowires and has to be taken into account in the calculations. Our conclusion is different from that of an earlier study which attributed the very low thermal conductivity to the unusually large mass-difference scattering in the nanowires
Revivals of quantum wave-packets in graphene
We investigate the propagation of wave-packets on graphene in a perpendicular
magnetic field and the appearance of collapses and revivals in the
time-evolution of an initially localised wave-packet. The wave-packet evolution
in graphene differs drastically from the one in an electron gas and shows a
rich revival structure similar to the dynamics of highly excited Rydberg
states.
We present a novel numerical wave-packet propagation scheme in order to solve
the effective single-particle Dirac-Hamiltonian of graphene and show how the
collapse and revival dynamics is affected by the presence of disorder. Our
effective numerical method is of general interest for the solution of the Dirac
equation in the presence of potentials and magnetic fields.Comment: 22 pages, 10 figures, 3 movies, to appear in New Journal of Physic
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