G\"odel-type Spacetimes in Induced Matter Gravity Theory

A five-dimensional (5D) generalized G\"odel-type manifolds are examined in the light of the equivalence problem techniques, as formulated by Cartan. The necessary and sufficient conditions for local homogeneity of these 5D manifolds are derived. The local equivalence of these homogeneous Riemannian manifolds is studied. It is found that they are characterized by three essential parameters $k$, $m^2$ and $\omega$: identical triads $(k, m^2, \omega)$ correspond to locally equivalent 5D manifolds. An irreducible set of isometrically nonequivalent 5D locally homogeneous Riemannian generalized G\"odel-type metrics are exhibited. A classification of these manifolds based on the essential parameters is presented, and the Killing vector fields as well as the corresponding Lie algebra of each class are determined. It is shown that the generalized G\"odel-type 5D manifolds admit maximal group of isometry $G_r$ with $r=7$, $r=9$ or $r=15$ depending on the essential parameters $k$, $m^2$ and $\omega$. The breakdown of causality in all these classes of homogeneous G\"odel-type manifolds are also examined. It is found that in three out of the six irreducible classes the causality can be violated. The unique generalized G\"odel-type solution of the induced matter (IM) field equations is found. The question as to whether the induced matter version of general relativity is an effective therapy for these type of causal anomalies of general relativity is also discussed in connection with a recent article by Romero, Tavakol and Zalaletdinov.Comment: 19 pages, Latex, no figures. To Appear in J.Math.Phys.(1999

Augmented Reality based monitoring of the remote-lab

© 2014 IEEE. Augmented Reality technology approach has been being adopted within the education sector. The advanced technology tools in many classes have the potential changed of users' attitudes toward the pedagogical and psychological objectives and goals. Moreover, augmented reality has not elicited so much attention within the corridors of education sector as it is now. In order to improve the interactive effectiveness in the smart classroom environment, there is a demand to tailor the innovation technology and align it with every changing requirements and capabilities of various users. Consequently, the educators are increasingly finding augmented reality suitable for deployment in education. In this paper, a project shows how Augmented Reality utilised with overlay Smart-Grid can support the learning process in attractive methods for monitoring events of captured scenes in remote-lab such as video stream, Web-link from smart devices' camera

Big brother is watching - using digital disease surveillance tools for near real-time forecasting

Abstract for the International Journal of Infectious Diseases 79 (S1) (2019).https://www.ijidonline.com/article/S1201-9712(18)34659-9/abstractPublished versio

Glueball Regge trajectories from gauge/string duality and the Pomeron

The spectrum of light baryons and mesons has been reproduced recently by Brodsky and Teramond from a holographic dual to QCD inspired in the AdS/CFT correspondence. They associate fluctuations about the AdS geometry with four dimensional angular momenta of the dual QCD states. We use a similar approach to estimate masses of glueball states with different spins and their excitations. We consider Dirichlet and Neumann boundary conditions and find approximate linear Regge trajectories for these glueballs. In particular the Neumann case is consistent with the Pomeron trajectory.Comment: In this revised version we made some additional remarks on the text. We also included 2 more references. The glueball spectrum and Regge trajectories are unchanged. 10 pages, 2 eps figure

Satellite laser ranging work at the Goddard Space Flight Center

Laser ranging systems, their range and accuracy capabilities, and planned improvements for future systems are discussed, the systems include one fixed and two mobile lasers ranging systems. They have demonstrated better than 10 cm accuracy both on a carefully surveyed ground range and in regular satellite ranging operations. They are capable of ranging to all currently launched retroreflector equipped satellites with the exception of Timation III. A third mobile system is discussed which will be accurate to better than 5 cm and will be capable of ranging to distant satellites such as Timation III and LAGEOS

On Supergroups with Odd Clifford Parameters and Supersymmetry with Modified Leibniz Rule

We investigate supergroups with Grassmann parameters replaced by odd Clifford parameters. The connection with non-anticommutative supersymmetry is discussed. A Berezin-like calculus for odd Clifford variables is introduced. Fermionic covariant derivatives for supergroups with odd Clifford variables are derived. Applications to supersymmetric quantum mechanics are made. Deformations of the original supersymmetric theories are encountered when the fermionic covariant derivatives do not obey the graded Leibniz property. The simplest non-trivial example is given by the N=2 SQM with a real $(1,2,1)$ multiplet and a cubic potential. The action is real. Depending on the overall sign ("Euclidean" or "Lorentzian") of the deformation, a Bender-Boettcher pseudo-hermitian hamiltonian is encountered when solving the equation of motion of the auxiliary field. A possible connection of our framework with the Drinfeld twist deformation of supersymmetry is pointed out.Comment: Final version to be published in Int. J. Mod. Phys. A; 20 page

High genetic variability of HIV-1 in female sex workers from Argentina

<p>Abstract</p> <p>Background</p> <p>A cross-sectional study on 625 Female Sex Workers (FSWs) was conducted between 2000 and 2002 in 6 cities in Argentina. This study describes the genetic diversity and the resistance profile of the HIV-infected subjects.</p> <p>Results</p> <p>Seventeen samples from HIV positive FSWs were genotyped by <it>env </it>HMA, showing the presence of 9 subtype F, 6 subtype B and 2 subtype C. Sequence analysis of the protease/RT region on 16 of these showed that 10 were BF recombinants, three were subtype B, two were subtype C, and one sample presented a dual infection with subtype B and a BF recombinant. Full-length genomes of five of the protease/RT BF recombinants were also sequenced, showing that three of them were CRF12_BF. One FSW had a dual HIV-1 infection with subtype B and a BF recombinant. The B sections of the BF recombinant clustered closely with the pure B sequence isolated from the same patient. Major resistance mutations to antiretroviral drugs were found in 3 of 16 (18.8%) strains.</p> <p>Conclusion</p> <p>The genetic diversity of HIV strains among FSWs in Argentina was extensive; about three-quarters of the samples were infected with diverse BF recombinants, near twenty percent had primary ART resistance and one sample presented a dual infection. Heterosexual transmission of genetically diverse, drug resistant strains among FSWs and their clients represents an important and underestimated threat, in Argentina.</p

Mechanical Strength of 17 134 Model Proteins and Cysteine Slipknots

A new theoretical survey of proteins' resistance to constant speed stretching is performed for a set of 17 134 proteins as described by a structure-based model. The proteins selected have no gaps in their structure determination and consist of no more than 250 amino acids. Our previous studies have dealt with 7510 proteins of no more than 150 amino acids. The proteins are ranked according to the strength of the resistance. Most of the predicted top-strength proteins have not yet been studied experimentally. Architectures and folds which are likely to yield large forces are identified. New types of potent force clamps are discovered. They involve disulphide bridges and, in particular, cysteine slipknots. An effective energy parameter of the model is estimated by comparing the theoretical data on characteristic forces to the corresponding experimental values combined with an extrapolation of the theoretical data to the experimental pulling speeds. These studies provide guidance for future experiments on single molecule manipulation and should lead to selection of proteins for applications. A new class of proteins, involving cystein slipknots, is identified as one that is expected to lead to the strongest force clamps known. This class is characterized through molecular dynamics simulations.Comment: 40 pages, 13 PostScript figure

Godel-type Universes in String-inspired Charged Gravity

We consider a string-inspired, gravitational theory of scalar and electromagnetic fields and we investigate the existence of axially-symmetric, G\"{o}del-type cosmological solutions. The neutral case is studied first and an "extreme" G\"{o}del-type rotating solution, that respects the causality, is determined. The charged case is considered next and two new configurations for the, minimally-coupled to gravity, electromagnetic field are presented. Another configuration motivated by the expected distribution of currents and charges in a rotating universe is studied and shown to lead to a G\"{o}del-type solution for a space-dependent coupling function. Finally, we investigate the existence of G\"{o}del-type cosmological solutions in the framework of the one-loop corrected superstring effective action and we determine the sole configuration of the electromagnetic field that leads to such a solution. It turns out that, in all the charged cases considered, Closed Timelike Curves do appear and the causality is always violated.Comment: 26 pages, LaTex file, a few comments and references added, version to appear in Physical Review

LRRK2 G2019S kinase activity triggers neurotoxic NSF aggregation

Parkinson’s disease is characterized by the progressive degeneration of dopaminergic neurons within the substantia nigra pars compacta and the presence of protein aggregates in surviving neurons. The LRRK2 G2019S mutation is one of the major determinants of familial Parkinson’s disease cases and leads to late-onset Parkinson’s disease with pleomorphic pathology, including α-synuclein accumulation and deposition of protein inclusions. We demonstrated that LRRK2 phosphorylates N-ethylmaleimide sensitive factor (NSF). We observed aggregates containing NSF in basal ganglia specimens from patients with Parkinson’s disease carrying the G2019S variant, and in cellular and animal models expressing the LRRK2 G2019S variant. We found that LRRK2 G2019S kinase activity induces the accumulation of NSF in toxic aggregates. Of note, the induction of autophagy cleared NSF aggregation and rescued motor and cognitive impairment observed in aged hG2019S bacterial artificial chromosome (BAC) mice. We suggest that LRRK2 G2019S pathological phosphorylation impacts on NSF biochemical properties, thus causing the formation of cytotoxic protein inclusions