180 research outputs found

    Occasional Collocations in Poetry of P. B. Shelley and Their Typology

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    The article is devoted to the functional-semantic analysis of occasional collocations in the poetry of P. B. Shelley. Occasional collocation refers to a special type of lexical units - individual author’s combinations of words, in which, as a rule, the lexical-semantic combinability is intentionally violated to attract the attention of readers to an unusual use of words. The relevance of this study is determined by the fact that occasional collocations are, firstly, one of the most expressive means of aesthetic enrichment of the artwork, and secondly, valuable linguistic material to study. The purpose of this article is to conduct a comprehensive analysis of occasional collocations for defining the meaning of the units, identifying mechanisms of their formation and establishment of the functions of collocations in the context of the works of P. B. Shelley and their belonging to a particular taxonomic type. In the analysis the author identifies several types of occasional units, creating the originality of poet’s lyrics: the author’s metaphors, deliberate pleonasms, inter-perception transfer, epithets, combinations of words, containing the opposite semes and at the same time having common semes to create occasional meaning. It is emphasized that the creation of occasional collocations is a characteristic feature of the author’s style of Shelley

    Occasional Combinatorial Lexicology as an Area of Study of Occasional Collocations

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    The article is devoted to occasional combinatorial lexicology as a separate area of combinatorial linguistics, more precisely, to lexicology studying occasional collocations, or atypical, individually authored and non-reproducible word combinations created through deliberate violation of lexico-semantic compatibility for performing certain functionally expressive tasks within a specific text. Particular attention is paid to the fact that the authors create and include occasional collocations for various purposes: first, to express an unconventional attitude to the object or subject described, secondly, to give it its own characteristic, thirdly, to put a certain emphasis on any part of the narration, etc. The technique of the functional-semantic analysis of occasional collocations as the basic, complex method of investigation is presented in the article, and features of this type of collocations are revealed. The authors believe that the allocation of occasional combinatorial lexicology contributes to the development and improvement of combinatorial science and the lexicological branch, provides scientifically substantiated interpretation and description of special lexical units - occasional collocations

    Introduction of information technologies as a tool of effective development of educational institution

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    В статье рассматриваются вопросы информатизации образовательного учреждения на примере реализованных проектов в ГОУ СПО СО «Уральский колледж строительства, архитектуры и предпринимательства».In this article we examine some questions about spreading of information technologies in educational institution and as an example we used the projects implemented in Ural College of Construction, Architecture and Enterprise

    New personalized genetic mouse model of Lesch-Nyhan syndrome for pharmacology and gene therapy

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    In the current study, we present the results of the generation of a genetically modified mouse strain carrying a deletion in the HPRT1 gene. These mice can be effectively used for the preclinical testing of new drugs aimed at the treatment of Lesch-Nyhan syndrom

    Complications at the hip replacement and ways of their prediction (review of literature)

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    The review presents modern data on the role of immune system in development of postoperative complications at hip replacement. Surgical stress while having depressive influence on immune system is powerful factor that causes conditions for development of secondary immune depression or intensifies it. On this background possibility of development of both early and late postoperative complications is quite high, that's why frequency of revision hip replacement increases steadily. Providing of stability of endoprosthesis is extremely important at total hip replacement. Researches realized during last decades determined connection of processes of osteogenesis and bone resorption and polypeptide factors of growth - cytokines. That's why questions of prevention and. correction of loss of bone substance with use of modern pharmacological preparations are important in the movement of observed problem. Infectious complications are also very significant ones at hip replacement. The fact of infectious process being the result of interrelation of macro- and. microorganisms and. immune system having one the leading roles in this process is doubtless. Among all the measures for prevention of postoperative complications their prevention that allows to determine right tactics of operative treatment, to realize complex of preparatory and. rehabilitation measures and. to improve the results of treatment and quality of life of patient, becomes important. Use of immunologic methods allowed to choose criteria and to develop ways of prevention of development of complications at hip replacement. However proposed ways not always allow to count individual susceptibility of an organism to different infectious pathogens; most of them are based on the determination of various specific and. quite laborious indices. Necessity of realization of researches before an operation and. in different terms of postoperative period for determination of dynamic dependence of changes of laboratory indices is significant disadvantage and requires quite prolonged observation of the patient for getting an information about prevention of hip replacement results. That's why further development and use of new ways of early hip replacement undoubtedly allows to improve results of surgical treatment of patients with different forms of coxarthrosis

    ROLE OF INTERFERONS IN REGULATION OF OSTOGENIC AND OSTEORESORPTIVE PROCESSES

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    Bone tissue preserves high metabolic activity during all time of its life. Homeostasis of bone tissue is provided by fine balance between its formation by osteoblasts and its resorption by osteoclasts. There are complex regulatory interrelations between cells of bone differon and. system of interferons, the peculiarities of production of which mediate disturbances of osteoformating and. resorptive components of osteo metabolism at various pathological conditions. The review presents literature data on the role of interferons in regulation of osteogenous and. osteoresorptive processes which opens up the prospective of aimed application of interferons preparations with the purpose of restoration of immunologic imbalance and. bone tissue homeostasis
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