20 research outputs found
A facility to Search for Hidden Particles (SHiP) at the CERN SPS
A new general purpose fixed target facility is proposed at the CERN SPS
accelerator which is aimed at exploring the domain of hidden particles and make
measurements with tau neutrinos. Hidden particles are predicted by a large
number of models beyond the Standard Model. The high intensity of the SPS
400~GeV beam allows probing a wide variety of models containing light
long-lived exotic particles with masses below (10)~GeV/c,
including very weakly interacting low-energy SUSY states. The experimental
programme of the proposed facility is capable of being extended in the future,
e.g. to include direct searches for Dark Matter and Lepton Flavour Violation.Comment: Technical Proposa
A facility to Search for Hidden Particles (SHiP) at the CERN SPS
A new general purpose fixed target facility is proposed at the CERN SPS accelerator which is aimed at exploring the domain of hidden particles and make measurements with tau neutrinos. Hidden particles are predicted by a large number of models beyond the Standard Model. The high intensity of the SPS 400~GeV beam allows probing a wide variety of models containing light long-lived exotic particles with masses below (10)~GeV/c, including very weakly interacting low-energy SUSY states. The experimental programme of the proposed facility is capable of being extended in the future, e.g. to include direct searches for Dark Matter and Lepton Flavour Violation
Genetic landscape in Russian patients with familial left ventricular noncompaction
BackgroundLeft ventricular noncompaction (LVNC) cardiomyopathy is a disorder that can be complicated by heart failure, arrhythmias, thromboembolism, and sudden cardiac death. The aim of this study is to clarify the genetic landscape of LVNC in a large cohort of well-phenotyped Russian patients with LVNC, including 48 families (n=214).MethodsAll index patients underwent clinical examination and genetic analysis, as well as family members who agreed to participate in the clinical study and/or in the genetic testing. The genetic testing included next generation sequencing and genetic classification according to ACMG guidelines.ResultsA total of 55 alleles of 54 pathogenic and likely pathogenic variants in 24 genes were identified, with the largest number in the MYH7 and TTN genes. A significant proportion of variants −8 of 54 (14.8%) −have not been described earlier in other populations and may be specific to LVNC patients in Russia. In LVNC patients, the presence of each subsequent variant is associated with increased odds of having more severe LVNC subtypes than isolated LVNC with preserved ejection fraction. The corresponding odds ratio is 2.77 (1.37 −7.37; p <0.001) per variant after adjustment for sex, age, and family.ConclusionOverall, the genetic analysis of LVNC patients, accompanied by cardiomyopathy-related family history analysis, resulted in a high diagnostic yield of 89.6%. These results suggest that genetic screening should be applied to the diagnosis and prognosis of LVNC patients
A facility to Search for Hidden Particles (SHiP) at the CERN SPS
A new general purpose fixed target facility is proposed at the CERN SPS accelerator which is aimed at exploring the domain of hidden particles and make measurements with tau neutrinos. Hidden particles are predicted by a large number of models beyond the Standard Model. The high intensity of the SPS 400~GeV beam allows probing a wide variety of models containing light long-lived exotic particles with masses below (10)~GeV/c, including very weakly interacting low-energy SUSY states. The experimental programme of the proposed facility is capable of being extended in the future, e.g. to include direct searches for Dark Matter and Lepton Flavour Violation
АНАЛІЗ МОДЕЛЕЙ РОЗРАХУНКУ ТРУБ СИСТЕМИ «КОНСТРУКЦІЯ-ҐРУНТ»
Recently in the European countries the designs of flexible pipes and pipe bridges, the bearing capacity of which is provided by passive resistance of soil, have found more applications. The paper presents an analysis of existing models for calculating flexible pipes working as a system «construction-soil». The numerical example for calculating such construction design using software package SCAD is given.В последнее время в странах Европы стали чаще применятся конструкции гибких труб и труб-мостов, несущая способность которых обеспечивается пассивным сопротивлением грунта. В статье представлен анализ существующих моделей расчета гибких труб, работающих как система «конструкция-грунт», приведен пример расчета такой конструкции в программном комплексе SCAD.Останнім часом в країнах Європи набули поширення конструкції гнучких труб та труб-мостів, несна здатність яких забезпечується завдяки пасивному опору ґрунту. В статті представлено аналіз існуючих моделей розрахунку гнучких труб, що працюють як система «конструкція-ґрунт», та наведено приклад розрахунку такої конструкції в програмному комплексі SCAD
ANALYSIS OF FUNNELS EVALUATION MODEL BY THE “CONSTRUCTION-SOIL” SYSTEM
Recently in the European countries the designs of flexible pipes and pipe bridges, the bearing capacity of which is provided by passive resistance of soil, have found more applications. The paper presents an analysis of existing models for calculating flexible pipes working as a system «construction-soil». The numerical example for calculating such construction design using software package SCAD is given
Automatic measuring complex of main parameters of liquids. Part 2
В работе приведены результаты разработки и экспериментального исследования акустического уровнемера погружного типа, предназначенного для измерения различных параметров жидкости в резервуарах, в том числе во взрывоопасных зонах. Получены аналитические выражения для калибровки и учета погрешностей прибора.Наведені результати розробки та експериментального дослідження акустичного ультразвукового рівнеміра занурюваного типу.In work are brought results of development and experimental study acoustic ultrasonic level gauge submersible type
RadioPhysical methods of determination of component composition of fine-dyspersated mixtures. Part 2
Приведены результаты анализа радиофизических методов и экспериментальные данные по использованию аппаратуры сантиметрового и миллиметрового диапазонов длин волн для определения процентного содержания компонент мелкодисперсных смесей на различных стадиях технологического процесса.Наведені результати аналітичного дослідження радіофізичних методів визначення компонентного складу дрібнодисперсних сумішей на різних стадіях технологічного процесу.Brought results of analytical study of radiophysical methods of determination of component composition of fine-dyspersated mixtures on different stages of technological process