1,042 research outputs found

    Probabilistic analysis of bladed turbine disks and the effect of mistuning

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    Probabilistic assessment of the maximum blade response on a mistuned rotor disk is performed using the computer code NESSUS. The uncertainties in natural frequency, excitation frequency, amplitude of excitation and damping are included to obtain the cumulative distribution function (CDF) of blade responses. Advanced mean value first order analysis is used to compute CDF. The sensitivities of different random variables are identified. Effect of the number of blades on a rotor on mistuning is evaluated. It is shown that the uncertainties associated with the forcing function parameters have significant effect on the response distribution of the bladed rotor

    Rapid Prediction of Moments in High-rise Composite Frames Considering Cracking and Time-effects

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    There can be a significant amount of moment redistribution in steel concrete composite frames due to cracking, creep and shrinkage in concrete. In the present study, neural network models have been developed for rapid prediction of the inelastic moments (typically for 20 years considering cracking, creep and shrinkage in concrete) in high rise composite frames. The possibility of sagging moment being developed at ends of beams due to the substantial differential shortening of adjacent columns has also been taken into account. Closed form expressions, based on the weights and biases of the trained neural networks, are proposed to predict the inelastic moments from the elastic moments (neglecting cracking and time effects). The expressions are verified for example frames of different number of spans and storeys and errors are found to be small. The expressions require computational effort that is a fraction of that required for the available methods

    Analysis with observational constraints in Λ \Lambda -cosmology in f(R,T)f(R,T) gravity

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    An exact cosmological solution of Einstein field equations (EFEs) is derived for a dynamical vacuum energy in f(R,T)f(R,T) gravity for Friedmann-Lemaitre-Robertson-Walker (FLRW) space-time. A parametrization of the Hubble parameter is used to find a deterministic solution of EFE. The cosmological dynamics of our model is discussed in detail. We have analyzed the time evolution of physical parameters and obtained their bounds analytically. Moreover, the behavior of these parameters are shown graphically in terms of redshift z`z'. Our model is consistent with the formation of structure in the Universe. The role of the f(R,T)f(R,T) coupling constant λ\lambda is discussed in the evolution of the equation of state parameter. The statefinder and Om diagnostic analysis is used to distinguish our model with other dark energy models. The maximum likelihood analysis has been reviewed to obtain the constraints on the Hubble parameter H0H_0 and the model parameter nn by taking into account the observational Hubble data set H(z)H(z), the Union 2.1 compilation data set SNeIaSNeIa, the Baryon Acoustic Oscillation data BAOBAO, and the joint data set H(z)H(z) + SNeIa SNeIa and H(z)H(z) + SNeIaSNeIa + BAOBAO . It is demonstrated that the model is in good agreement with various observations.Comment: 21 PAGES, 20 FIGURE

    Endoscopic tunneling of HeartMate II left ventricular assist device driveline

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    Probabilistic Estimation of Critical Flaw Sizes in the Primary Structure Welds of the Ares I-X Launch Vehicle

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    The primary structure of the Ares I-X Upper Stage Simulator (USS) launch vehicle is constructed of welded mild steel plates. There is some concern over the possibility of structural failure due to welding flaws. It was considered critical to quantify the impact of uncertainties in residual stress, material porosity, applied loads, and material and crack growth properties on the reliability of the welds during its pre-flight and flight. A criterion--an existing maximum size crack at the weld toe must be smaller than the maximum allowable flaw size--was established to estimate the reliability of the welds. A spectrum of maximum allowable flaw sizes was developed for different possible combinations of all of the above listed variables by performing probabilistic crack growth analyses using the ANSYS finite element analysis code in conjunction with the NASGRO crack growth code. Two alternative methods were used to account for residual stresses: (1) The mean residual stress was assumed to be 41 ksi and a limit was set on the net section flow stress during crack propagation. The critical flaw size was determined by parametrically increasing the initial flaw size and detecting if this limit was exceeded during four complete flight cycles, and (2) The mean residual stress was assumed to be 49.6 ksi (the parent material s yield strength) and the net section flow stress limit was ignored. The critical flaw size was determined by parametrically increasing the initial flaw size and detecting if catastrophic crack growth occurred during four complete flight cycles. Both surface-crack models and through-crack models were utilized to characterize cracks in the weld toe

    Probabilistic evaluation of uncertainties and risks in aerospace components

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    This paper summarizes a methodology developed at NASA Lewis Research Center which computationally simulates the structural, material, and load uncertainties associated with Space Shuttle Main Engine (SSME) components. The methodology was applied to evaluate the scatter in static, buckling, dynamic, fatigue, and damage behavior of the SSME turbo pump blade. Also calculated are the probability densities of typical critical blade responses, such as effective stress, natural frequency, damage initiation, most probable damage path, etc. Risk assessments were performed for different failure modes, and the effect of material degradation on the fatigue and damage behaviors of a blade were calculated using a multi-factor interaction equation. Failure probabilities for different fatigue cycles were computed and the uncertainties associated with damage initiation and damage propagation due to different load cycle were quantified. Evaluations on the effects of mistuned blades on a rotor were made; uncertainties in the excitation frequency were found to significantly amplify the blade responses of a mistuned rotor. The effects of the number of blades on a rotor were studied. The autocorrelation function of displacements and the probability density function of the first passage time for deterministic and random barriers for structures subjected to random processes also were computed. A brief discussion was included on the future direction of probabilistic structural analysis

    Shrouded CMC Rotor Blades for High Pressure Turbine Applications

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    The density of Ceramic Matrix Compos-ite(CMC) materials is approximately 1/3 the density of metals currently used for High Pressure Turbine(HPT) blades. A lower density, and consequently lower centrifugal stresses, increases the feasibility of shrouding HPT blades. Shrouding HPT blades improves aerodynamic eciency, especially for low aspect ratio turbine blades. This paper explores aerodynamic and structural issues associated with shrouding HPT rotor blades. Detailed Navier-Stokes analysis of a rotor blade showed that shrouding improved blade row aerodynamic eciency by 1.3%, when the clearance was 2% of the blade span. Recessed casings were used. Without a shroud the depth of the recess equaled the clearance. With a shroud the recess depth increased by the shroud thickness, which included a knife seal. There was good agreement between the predicted stage eciency for the unshrouded blades and the experimentally measured efficiency. Structural analysis showed a strong interaction between stresses in the shroud and peak stresses at the hub of the blade. A thin shroud of uniform thickness only moderately increased maximum blade stress, but there were very high stresses in the shroud itself. Increasing shroud thickness reduced stresses in the shroud, but increased blade stresses near the hub. A single knife seal added to the thin shroud noticeably decreased maximum shroud stress, without increasing maximum blade stress. Maximum stresses due to pressure loads and combined pressure and centrifugal loads were nearly the same as the maximum stresses for individual pressure or cen-trifugal loads. Stresses due to a 100K temperatur

    Neurofilament Heavy Polypeptide Regulates the Akt-β-Catenin Pathway in Human Esophageal Squamous Cell Carcinoma

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    Aerobic glycolysis and mitochondrial dysfunction are common features of aggressive cancer growth. We observed promoter methylation and loss of expression in neurofilament heavy polypeptide (NEFH) in a significant proportion of primary esophageal squamous cell carcinoma (ESCC) samples that were of a high tumor grade and advanced stage. RNA interference-mediated knockdown of NEFH accelerated ESCC cell growth in culture and increased tumorigenicity in vivo, whereas forced expression of NEFH significantly inhibited cell growth and colony formation. Loss of NEFH caused up-regulation of pyruvate kinase-M2 type and down-regulation of pyruvate dehydrogenase, via activation of the Akt/β-catenin pathway, resulting in enhanced aerobic glycolysis and mitochondrial dysfunction. The acceleration of glycolysis and mitochondrial dysfunction in NEFH-knockdown cells was suppressed in the absence of β-catenin expression, and was decreased by the treatment of 2-Deoxyglucose, a glycolytic inhibitor, or API-2, an Akt inhibitor. Loss of NEFH activates the Akt/β-catenin pathway and increases glycolysis and mitochondrial dysfunction. Cancer cells with methylated NEFH can be targeted for destruction with specific inhibitors of deregulated downstream pathways
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