In Situ Environmental Scanning Electron Microscopy (ESEM) of Semi-Solid Samples

The ESEM (Environmental Scanning Electron Microscope) is an instrument that circumvents a limitation of conventional SEM, in that samples can be examined in a gaseous atmosphere rather than a vacuum. With a heating stage, dynamic processes can be observed in situ at high temperature. In this study, A201 aluminium alloy samples with globular structures have been examined in the semisolid region. In addition, a manipulator has been installed onto the heating stage to allow the probing of semi-solid surfaces. The paper shows the potential for manipulating semi-solid materials in order to better understand thixotropic phenomena

The Herschel Multi-Tiered Extragalactic Survey: source extraction and cross-identifications in confusion-dominated SPIRE images

We present the cross-identification and source photometry techniques used to process Herschel SPIRE imaging taken as part of the Herschel Multi-Tiered Extragalactic Survey (HerMES). Cross-identifications are performed in map-space so as to minimize source-blending effects. We make use of a combination of linear inversion and model selection techniques to produce reliable cross-identification catalogues based on Spitzer MIPS 24-μm source positions. Testing on simulations and real Herschel observations shows that this approach gives robust results for even the faintest sources (S250∼ 10 mJy). We apply our new technique to HerMES SPIRE observations taken as part of the science demonstration phase of Herschel. For our real SPIRE observations, we show that, for bright unconfused sources, our flux density estimates are in good agreement with those produced via more traditional point source detection methods (SUSSEXtractor) by Smith et al. When compared to the measured number density of sources in the SPIRE bands, we show that our method allows the recovery of a larger fraction of faint sources than these traditional methods. However, this completeness is heavily dependent on the relative depth of the existing 24-μm catalogues and SPIRE imaging. Using our deepest multiwavelength data set in the GOODS-N, we estimate that the use of shallow 24-μm catalogues in our other fields introduces an incompleteness at faint levels of between 20–40 per cent at 250 μm

The Deep SPIRE HerMES Survey: spectral energy distributions and their astrophysical indications at high redshift

The Spectral and Photometric Imaging Receiver on-board Herschel has been carrying out deep extragalactic surveys, one of the aims of which is to establish spectral energy distributions of individual galaxies spanning the infrared/submillimetre (IR/SMM) wavelength region. We report observations of the IR/SMM emission from the Lockman North field and Great Observatories Origins Deep Survey Field-North. Because galaxy images in the wavelength range covered by Herschel generally represent a blend with contributions from neighbouring galaxies, we present sets of galaxies in each field, especially free of blending at 250, 350 and 500 μm. We identify the cumulative emission of these galaxies and the fraction of the FIR cosmic background radiation they contribute. Our surveys reveal a number of highly luminous galaxies at redshift z≲ 3 and a novel relationship between IR and visible emission that shows a dependence on luminosity and redshift

Evolution of dust temperature of galaxies through cosmic time as seen by Herschel

We study the dust properties of galaxies in the redshift range 0.1 ≲z≲ 2.8 observed by the Herschel Space Observatory in the field of the Great Observatories Origins Deep Survey-North as part of the PACS Extragalactic Probe (PEP) and Herschel Multi-tiered Extragalactic Survey (HerMES) key programmes. Infrared (IR) luminosity (LIR) and dust temperature (Tdust) of galaxies are derived from the spectral energy distribution fit of the far-IR (FIR) flux densities obtained with the PACS and SPIRE instruments onboard Herschel. As a reference sample, we also obtain IR luminosities and dust temperatures of local galaxies at z < 0.1 using AKARI and IRAS data in the field of the Sloan Digital Sky Survey. We compare the LIR–Tdust relation between the two samples and find that the median Tdust of Herschel-selected galaxies at z≳ 0.5 with LIR≳ 5 × 1010 L⊙ appears to be 2–5 K colder than that of AKARI-selected local galaxies with similar luminosities, and the dispersion in Tdust for high-z galaxies increases with LIR due to the existence of cold galaxies that are not seen among local galaxies. We show that this large dispersion of the LIR−Tdust relation can bridge the gap between local star-forming galaxies and high-z submillimetre galaxies (SMGs). We also find that three SMGs with very low Tdust (≲20 K) covered in this study have close neighbouring sources with similar 24-μm brightness, which could lead to an overestimation of FIR/(sub)millimetre fluxes of the SMGs

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.

To dissect the genetic architecture of blood pressure and assess effects on target organ damage, we analyzed 128,272 SNPs from targeted and genome-wide arrays in 201,529 individuals of European ancestry, and genotypes from an additional 140,886 individuals were used for validation. We identified 66 blood pressure-associated loci, of which 17 were new; 15 harbored multiple distinct association signals. The 66 index SNPs were enriched for cis-regulatory elements, particularly in vascular endothelial cells, consistent with a primary role in blood pressure control through modulation of vascular tone across multiple tissues. The 66 index SNPs combined in a risk score showed comparable effects in 64,421 individuals of non-European descent. The 66-SNP blood pressure risk score was significantly associated with target organ damage in multiple tissues but with minor effects in the kidney. Our findings expand current knowledge of blood pressure-related pathways and highlight tissues beyond the classical renal system in blood pressure regulation