3 research outputs found
Voluntary Refusal to Commit a Crime: Significance, General and Special Signs
The article describes and examines the significance of the rule of the voluntary refusal to commit a crime, as well as explores its general and special signs. It is noted that the voluntary refusal to commit a crime is the rule contained in any modern, progressive law. In this vein, there are different theoretical approaches to the determination of its value and signs. The signs are debatable in nature, and their establishment by the law enforcer may cause difficulties. The difference between voluntary refusal to commit a crime, which is implemented in three functions, is determined, definitions of general signs of voluntary refusal are proposed, their content is clarified. Special signs of voluntary refusal are disclosed
Attempt: signs and types
The objective of this study was to analyze what was tempted by direct criminal science. A basic investigation is a dialectical approach to the dissemination of legal phenomena and processes, going through gerais scientific methods (systematic and logical methods, analysis and synthesis) and specific scientific methods. The results will show that the attempted crime was part of the objective side of a certain criminal corpus. The beginning of the attempt may coincide as the beginning of the constitutive act of the crime. Furthermore, an attempt is classified by the implementation of the intention as completed and not completed. And, finally, a special kind of attempt is a "futile attempt."An unsuccessful attempt must be subject to responsibility and qualification, bem as a common attempt
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Clinical significance of PlA polymorphism of platelet GP IIb/IIIa receptors during long-term VAD support
Although bleeding and thromboembolism remain major complications after implantation of ventricular assist devices (VADs), no standard anticoagulation protocols are available. Genetic polymorphism of platelet glycoprotein IIb/IIIa may contribute to the development of complications. The present study demonstrates a relationship between the PlA genotype and postoperative complications in patients implanted with pulsatile and axial flow VADs.
The PlA genotype was determined in 41 consecutive patients treated with a VAD who received anticoagulation with phenprocoumon and aspirin. Pulsatile Novacor (Novacor Corp, Oakland, CA) and Berlin Heart VADs (Berlin Heart, Berlin, Germany) were implanted in 28 patients and the axial flow MicroMed DeBakey VAD (MicroMed Technology, Inc, Houston, TX) in 13. The relationship between the PlA genotype, the anticoagulation regime, and bleeding and thromboembolic events was analyzed.
There were no differences between patients with the A1A1 and A1A2 genotype regarding demographic characteristics, weight, or infection episodes. The international normalized ratio (INR), platelet activation tests, and doses of aspirin and dipyridamol before events were similar in both groups. Patients with the A1A1 genotype developed more bleeding complications (39% vs 0%,
p = 0.021), while patients with the A1A2 genotype showed a tendency toward more thromboembolic events (13% vs 30%,
p = 0.33). With regard to different types of VAD, patients with the axial flow DeBakey VAD and the A1A1 genotype developed significantly more bleeding complications (70% vs 0%,
p = 0.033).
In patients with a long-term VAD determination of PlA polymorphism and subsequent adjustment of the anticoagulation regime may lead to a reduction of bleeding and thromboembolic complications