Tris(ethane-1,2-diamine)copper(II) bis­(trifluoro­acetate)

In the title complex, [Cu(H2NCH2CH2NH2)3](CF3COO)2, the environment of the Cu atom is distorted octa­hedral, formed by six N atoms from three chelating ethane-1,2-diamine ligands. The Cu—N distances range from 2.050 (2) to 2.300 (2) Å. This complex cation and the two trifluoro­acetate anions are connected by weak N—H⋯O and N—H⋯F hydrogen bonds, forming a three-dimensional framework. In both anions, the F atoms are disordered over two positions; in one the site-occupancy factors are 0.55 and 0.45, in the other the values are 0.69 and 0.31

Респираторная поддержка при тромбоэмболии легочной артерии (обзор)

Pulmonary artery thromboembolia (PATE) is not a clinical entity as such, but a complication of different diseases and conditions leading to deep thrombosis in the low tension circulation system, right cardiac chambers or causing local thrombosis in the pulmonary artery system. PATE is characterized by complex pathogenesis of respiratory failure of varying severity, which makes it difficult to choose a respiratory support technique.Purpose of the overview: to show advantages of different respiratory support techniques and prospects of high-flux oxygen therapy with regard to PATE pathophysiology.82 sources were selected based on the principle of combining clinical and experimental data from papers published over the recent 5 years and earlier that are still relevant for medical practice.The overview presents the structure of main causes and prevalence of PATE and considers thrombogenesis stages and predominant manifestations of respiratory failure during PATE occurring due to inconsistency between pulmonary ventilation and perfusion. Review discusses five methods of respiratory therapy in PATE patients: low-flux and high-flux oxygen therapy, non-invasive and invasive artificial lung ventilation, extracorporeal blood oxygenation. Finally, the paper shows the efficacy and limitations of these methods.Conclusion. High-flux oxygen therapy seems to be the most effective and promising technique in PATE patients thanks to absence of adverse cardiohemodynamic consequences, subjective comfort for patients, and relation to minimal risks of secondary infectious complications.Nevertheless, the clinical experience accumulated is insufficient to make an absolute choice of one particular technique for respiratory support during PATE. It is necessary to continue investigating the clinical efficacy of high-flux oxygen therapy in the specific population of patients who experienced PATE.Тромбоэмболия легочной артерии (ТЭЛА) — не самостоятельная нозологическая единица, а осложнение различных заболеваний и состояний, приводящих к возникновению глубоких тромбозов в венозной системе, правых камерах сердца, либо вызывающих местный тромбоз в системе легочной артерии. ТЭЛА характеризуется сложностью патогенеза развития дыхательной недостаточности различной степени выраженности, что обуславливает сложность выбора способов респираторной поддержки.Цель обзора. Показать возможности различных методов респираторной поддержки и перспективы применения высокопоточной оксигенотерапии с учетом патофизиологических особенностей ТЭЛА.Отбор 82 источников проводили по принципу сочетания клинических и экспериментальных данных из источников последних 5 лет и более ранних, сохранивших актуальность для медицинской практики.В обзоре представили структуру основных причин и частоту распространения ТЭЛА; рассмотрели этапы тромбогенеза и основные проявления дыхательной недостаточности при ТЭЛА, возникающие при несоответствии вентиляции и перфузии легких; привели 5 методов респираторной терапии у больных с ТЭЛА: низкопоточную и высокопоточную оксигенотерапию, неинвазивную и инвазивную искусственную вентиляцию легких, экстракорпоральную оксигенацию крови; показали эффективность и ограничения этих методов.Заключение. Метод высокопоточной оксигенотерапии представляется наиболее эффективным и перспективным у больных с ТЭЛА в связи с отсутствием негативных кардиогемодинамических последствий, субъективной комфортностью для пациентов, а также ввиду соотношения с минимальными рисками вторичных инфекционных осложнений.Тем не менее, накопленного клинического опыта недостаточно для однозначного выбора того или иного метода респираторной поддержки при ТЭЛА. Необходимо продолжение изучения клинической эффективности высокопоточной оксигенотерапии у специфического контингента больных, перенесших ТЭЛА

Metalloporphyrins on oxygen-passivated iron: Conformation and order beyond the first layer

On-surface metal porphyrins can undergo electronic and conformational changes that play a crucial role in determining the chemical reactivity of the molecular layer. Therefore, accessing those properties is pivotal for their implementation in organic-based devices. Here, by means of photoemission orbital tomography supported by density functional theory calculations, we investigate the electronic and geometrical structure of two metallated tetraphenyl porphyrins (MTPPs), namely ZnTPP and NiTPP, adsorbed on the oxygen-passivated Fe(100)-p(1 × 1)O surface. Both molecules weakly interact with the surface as no charge transfer is observed. In the case of ZnTPP, our data correspond to those of moderately distorted molecules whereas NiTPP exhibits a severe saddle-shape deformation. From additional experiments on NiTPP multilayer films, we conclude that this distortion is a consequence of the interaction with the substrate, as the NiTPP macrocycle of the second layer turns out to be flat. We further find that distortions in the MTPP macrocycle are accompanied by an increasing energy gap between the highest occupied molecular orbitals (HOMO and HOMO-1). Our results demonstrate that photoemission orbital tomography can simultaneously probe the energy level alignment, the azimuthal orientation, and the adsorption geometry of complex aromatic molecules even in the multilayer regime

Острый инфаркт миокарда как осложнение коронавирусной инфекции (клиническое наблюдение)

Coronavirus infection caused by the SARS-CoV-2 virus is a multifaceted disease due to generalized vascular endothelial damage. Endothelial damage also underlies COVID-associated coagulopathy.The paper presents a case of coagulopathy causing myocardial infarction in a 43-year-old patient with no history of coronary disease. We have reviewed the available literature for the pathophysiological rationale of the assumed possibility of coronary thrombosis resulting from coagulopathy with the intact intima of the coronary arteries.Conclusion. The present observation of coronary thrombosis with radiographically intact coronary artery intima confirms the important role of coronavirus infection in triggering endothelial dysfunction. Currently, the most effective strategy for this type of coronary lesions is the use of anticoagulants and antiplatelet agents along with ECG, echocardiography and troponin level monitoring.Коронавирусная инфекция, вызываемая вирусом SARS-CoV-2, является полиморфным заболеванием за счет генерализованного поражения эндотелия сосудов. Повреждение эндотелия лежит в основе ковид-ассоциированной коагулопатии.Привели наблюдение подобной коагулопатии, которая стала причиной острого инфаркта миокарда у 43-летнего мужчины без предшествующего коронарного анамнеза. Выполнили анализ доступных литературных источников на предмет патофизиологического обоснования гипотезы о возможности коронарного тромбоза как исхода ковид-ассоциированной коагулопатии при интактной интиме коронарных артерий.Заключение. Приведенное наблюдение подтверждает важную роль коронавирусной инфекциив запуске эндотелиальной дисфункции на примере коронарного тромбоза при рентгенологически интактной интиме венечных артерий. В настоящий момент наиболее эффективной тактикой при данном виде поражения коронарного русла остается антикоагулянтная и антиагрегантная терапия под контролем электрокардиографической, эхокардиографической картины и динамики тропонина

The Azimuthal Decorrelation of Jets Widely Separated in Rapidity

This study reports the first measurement of the azimuthal decorrelation between jets with pseudorapidity separation up to five units. The data were accumulated using the D{\O}detector during the 1992--1993 collider run of the Fermilab Tevatron at $\sqrt{s}=$ 1.8 TeV. These results are compared to next--to--leading order (NLO) QCD predictions and to two leading--log approximations (LLA) where the leading--log terms are resummed to all orders in $\alpha_{\scriptscriptstyle S}$. The final state jets as predicted by NLO QCD show less azimuthal decorrelation than the data. The parton showering LLA Monte Carlo {\small HERWIG} describes the data well; an analytical LLA prediction based on BFKL resummation shows more decorrelation than the data.Comment: 6 pages with 4 figures, all uuencoded and gzippe

Measurement of the WW Boson Mass

A measurement of the mass of the $W$ boson is presented based on a sample of 5982 $W \rightarrow e \nu$ decays observed in $p\overline{p}$ collisions at $\sqrt{s}$ = 1.8~TeV with the D\O\ detector during the 1992--1993 run. From a fit to the transverse mass spectrum, combined with measurements of the $Z$ boson mass, the $W$ boson mass is measured to be $M_W = 80.350 \pm 0.140 (stat.) \pm 0.165 (syst.) \pm 0.160 (scale) GeV/c^2$.Comment: 12 pages, LaTex, style Revtex, including 3 postscript figures (submitted to PRL

Search for Top Squark Pair Production in the Dielectron Channel

This report describes the first search for top squark pair production in the channel stop_1 stopbar_1 -> b bbar chargino_1 chargino_1 -> ee+jets+MEt using 74.9 +- 8.9 pb^-1 of data collected using the D0 detector. A 95% confidence level upper limit on sigma*B is presented. The limit is above the theoretical expectation for sigma*B for this process, but does show the sensitivity of the current D0 data set to a particular topology for new physics.Comment: Five pages, including three figures, submitted to PRD Brief Report

Search for a Fourth Generation Charge -1/3 Quark via Flavor Changing Neutral Current Decay

We report on a search for pair production of a fourth generation charge -1/3 quark (b') in pbar p collisions at sqrt(s) = 1.8 TeV at the Fermilab Tevatron using an integrated luminosity of 93 pb^-1. Both quarks are assumed to decay via flavor changing neutral currents (FCNC). The search uses the signatures gamma + 3 jets + mu-tag and 2 gamma + 2 jets. We see no significant excess of events over the expected background. We place an upper limit on the production cross section times branching fraction that is well below theoretical expectations for a b' quark decaying exclusively via FCNC for b' quark masses up to m(Z) + m(b).Comment: Eleven pages, two postscript figures, submitted to Physical Review Letter