STUDENT SOCIO-PSYCHOLOGICAL EXPECTATIONS FROM STUDYING IN HIGHER EDUCATION INSTITUTION: SATISFACTION DEGREE AND IMPLEMENTATION EVALUATION

O objetivo do estudo é analisar a implementação das expectativas dos alunos de estudar na Universidade. O método principal para o estudo desse problema é o método do questionário, que permite o estudo mais qualitativo e aprofundado das expectativas dos jovens em relação ao ensino superior. É revelado que os problemas existentes têm um impacto negativo na atitude dos alunos em relação à sua instituição educacional e, consequentemente, reduzir sua imagem aos olhos dos futuros alunos e do público em geral. Os dados obtidos neste trabalho podem ser utilizados nas áreas de psicologia da educação, psicologia da idade, psicologia social, pedagogia, sociologia, bem como para o desenvolvimento teórico adicional desta questão.El objetivo del estudio es analizar la implementación de las expectativas de los estudiantes al estudiar en la Universidad. El método principal para el estudio de este problema es el método del cuestionario, que permite el estudio más cualitativo y profundo de las expectativas de los jóvenes en relación con la educación superior. Se revela que los problemas existentes tienen un impacto negativo. sobre la actitud de los estudiantes hacia su institución educativa y, en consecuencia, reducir su imagen ante los futuros estudiantes y el público en general. Los datos obtenidos en este trabajo pueden utilizarse en psicología de la educación, psicología de la edad, psicología social, pedagogía, sociología, así como para un mayor desarrollo teórico de este tema.The aim of the study is to analyze the implementation of students' expectations from studying at the University. The leading method for the study of this problem is the method of the questionnaire, which allows the most qualitative and in-depth study of the expectations of young people in relation to higher education.. It is revealed that the existing problems have a negative impact on the attitude of students to their educational institution and, consequently, reduce its image in the eyes of future students and the public as a whole. The data obtained in this work can be used in the psychology of education, age psychology, social psychology, pedagogy, sociology, as well as for further theoretical development of this issue

МОРФОФУНКЦИОНАЛЬНЫЕ ХАРАКТЕРИСТИКИ САРКОМЫ М-1 КРЫС ПОСЛЕ ФОТОДИНАМИЧЕСКОЙ ТЕРАПИИ С ПРОИЗВОДНЫМ БАКТЕРИОХЛОРОФИЛЛА А

The study of the functional morphology of rat sarcoma M-1 after photodynamic therapy using bacteriopurpurinimide disulfide derivative (disulfide-BPI) as a photosensitizer is described. The research methods included immunohistochemistry for PCNA and CD31, evaluation of mitotic activity and apoptosis of tumor cells, as well as computer analysis of microscopic images. Photoinduced antitumor effect was shown to be due to the destruction of sarcoma M-1 vascular bed, the rapid inhibition of proliferative activity and devitalization of tumor cells by apoptosis and necrosis. It is reasonable to suppose that in the early stages after photodynamic therapy destruction of the microvasculature and photocytostatic shock of tumor cells with subsequent development of necrosis are caused by direct influence of the light flux on sensitized cellular elements in parenchyma and stroma of tumors. The efficiency of photodynamic therapy with the novel photosensitizer is determined by the sequence of destructive and inflammatory changes in tumor parenchyma and surrounding tissues, as well as repopulation potential of tumor cells survived after treatment.В работе описаны результаты изучения функциональной морфологии саркомы М-1 крыс после фотодинамической терапии с применением в качестве фотосенсибилизатора дисульфидного производного бактериопурпуринимида (дисульфид-БПИ). Методы исследования включали иммуноокрашивание на PCNA и CD31, определение митотической активности и апоптотической гибели опухолевых клеток, а также компьютерный анализ микроскопических изображений. Показано, что фотоиндуцированное противоопухолевое действие обусловлено разрушением сосудистого русла саркомы М-1, быстрым ингибированием пролиферативной активности и девитализацией опухолевых клеток путем апоптоза и некроза. Есть основания полагать, что в ранние сроки после фотодинамической терапии деструкция микроциркуляторного русла и фотоцитостатический шок опухолевых клеток с последующим развитием некроза обусловлены прямым воздействием светового потока на сенсибилизированные клеточные элементы паренхимы и стромы опухолей. Эффективность фотодинамической терапии с новым фотосенсибилизатором определяется последовательностью деструктивных и воспалительных изменений в паренхиме опухолей и окружающих тканях, а также репопуляционным потенциалом выживших после лечения опухолевых клеток

USE OF FERTILIZERS AND BIO MEDICINE FOR SUNFLOWER ON ORDINARY CHERNOZEM (BLACK SOIL)

In 2012-2013 we carried out field trials of sunflower hybrid ‘Patriot’ fertilizing it with bio fertilizers on ordinary chernozem of the central part of the Rostov region. Such fertilizers as ammonium phosphate and ammonium nitrate were added during presowing cultivation and bio fertilizer with microorganisms PG-5, 30 P, 7, 17-1 were used for seed processing. The use of N40Р50 dose of fertilizer increased sunflower productivity, oil content and oil yield per hectare on 24,6%, 3,2% and 33,7% respectively in comparison with a standard. The increase of the dose of phosphorus up to 100 kg/ha with presence of 15 mg/kg of moving phosphorus in soil didn’t greatly change these indexes. Nitrogen increase up to 80 kg/ha reduced these indexes but only with a high content of nitrogen in soil.  The seed treatment with bio medicine with microorganisms 7 and PG-5 gave good results. The productivity increased on 20,5%, the oil yield on 27,6 and 24,1%. The variants 30P and 17-1 are unstable to moisture deficit in soil and boiling temperature, which occurred in both years of trials

MORPHOFUNCTIONAL CHARACTERISTICS OF RAT SARCOMA M-1 AFTER PHOTODYNAMIC THERAPY WITH THE BACTERIOCHLOROPHYLL A DERIVATIVE

The study of the functional morphology of rat sarcoma M-1 after photodynamic therapy using bacteriopurpurinimide disulfide derivative (disulfide-BPI) as a photosensitizer is described. The research methods included immunohistochemistry for PCNA and CD31, evaluation of mitotic activity and apoptosis of tumor cells, as well as computer analysis of microscopic images. Photoinduced antitumor effect was shown to be due to the destruction of sarcoma M-1 vascular bed, the rapid inhibition of proliferative activity and devitalization of tumor cells by apoptosis and necrosis. It is reasonable to suppose that in the early stages after photodynamic therapy destruction of the microvasculature and photocytostatic shock of tumor cells with subsequent development of necrosis are caused by direct influence of the light flux on sensitized cellular elements in parenchyma and stroma of tumors. The efficiency of photodynamic therapy with the novel photosensitizer is determined by the sequence of destructive and inflammatory changes in tumor parenchyma and surrounding tissues, as well as repopulation potential of tumor cells survived after treatment.</p

MORPHOFUNCTIONAL CHARACTERISTICS OF RAT SARCOMA M-1 AFTER PHOTODYNAMIC THERAPY WITH THE BACTERIOCHLOROPHYLL A DERIVATIVE

The study of the functional morphology of rat sarcoma M-1 after photodynamic therapy using bacteriopurpurinimide disulfide derivative (disulfide-BPI) as a photosensitizer is described. The research methods included immunohistochemistry for PCNA and CD31, evaluation of mitotic activity and apoptosis of tumor cells, as well as computer analysis of microscopic images. Photoinduced antitumor effect was shown to be due to the destruction of sarcoma M-1 vascular bed, the rapid inhibition of proliferative activity and devitalization of tumor cells by apoptosis and necrosis. It is reasonable to suppose that in the early stages after photodynamic therapy destruction of the microvasculature and photocytostatic shock of tumor cells with subsequent development of necrosis are caused by direct influence of the light flux on sensitized cellular elements in parenchyma and stroma of tumors. The efficiency of photodynamic therapy with the novel photosensitizer is determined by the sequence of destructive and inflammatory changes in tumor parenchyma and surrounding tissues, as well as repopulation potential of tumor cells survived after treatment