Robust propagation direction of stresses in a minimal granular packing

By employing the adaptive network simulation method, we demonstrate that the ensemble-averaged stress caused by a local force for packings of frictionless rigid beads is concentrated along rays whose slope is consistent with unity: forces propagate along lines at 45 degrees to the horizontal or vertical. This slope is shown to be independent of polydispersity or the degree to which the system is sheared. Further confirmation of this result comes from fitting the components of the stress tensor to the null stress constitutive equation. The magnitude of the response is also shown to fall off with the -1/2 power of distance. We argue that our findings are a natural consequence of a system that preserves its volume under small perturbations.Comment: 8 pages, 6 figures. Some extra clarification and minor improvements. To appear in EPJ-

Tkachenko modes as sources of quasiperiodic pulsar spin variations

We study the long wavelength shear modes (Tkachenko waves) of triangular lattices of singly quantized vortices in neutron star interiors taking into account the mutual friction between the superfluid and the normal fluid and the shear viscosity of the normal fluid. The set of Tkachenko modes that propagate in the plane orthogonal to the spin vector are weakly damped if the coupling between the superfluid and normal fluid is small. In strong coupling, their oscillation frequencies are lower and are undamped for small and moderate shear viscosities. The periods of these modes are consistent with the observed ~100-1000 day variations in spin of PSR 1828-11.Comment: 7 pages, 3 figures, uses RevTex, v2: added discussion/references, matches published versio

Pinning and collective modes of a vortex lattice in a Bose-Einstein condensate

We consider the ground state of vortices in a rotating Bose-Einstein condensate that is loaded in a corotating two-dimensional optical lattice. Due to the competition between vortex interactions and their potential energy, the vortices arrange themselves in various patterns, depending on the strength of the optical potential and the vortex density. We outline a method to determine the phase diagram for arbitrary vortex filling factor. Using this method, we discuss several filling factors explicitly. For increasing strength of the optical lattice, the system exhibits a transition from the unpinned hexagonal lattice to a lattice structure where all the vortices are pinned by the optical lattice. The geometry of this fully pinned vortex lattice depends on the filling factor and is either square or triangular. For some filling factors there is an intermediate half-pinned phase where only half of the vortices is pinned. We also consider the case of a two-component Bose-Einstein condensate, where the possible coexistence of the above-mentioned phases further enriches the phase diagram. In addition, we calculate the dispersion of the low-lying collective modes of the vortex lattice and find that, depending on the structure of the ground state, they can be gapped or gapless. Moreover, in the half-pinned and fully pinned phases, the collective mode dispersion is anisotropic. Possible experiments to probe the collective mode spectrum, and in particular the gap, are suggested.Comment: 29 pages, 4 figures, changes in section

Colloids with key-lock interactions: non-exponential relaxation, aging and anomalous diffusion

The dynamics of particles interacting by key-lock binding of attached biomolecules are studied theoretically. Experimental realizations of such systems include colloids grafted with complementary single-stranded DNA (ssDNA), and particles grafted with antibodies to cell-membrane proteins. Depending on the coverage of the functional groups, we predict two distinct regimes. In the low coverage localized regime, there is an exponential distribution of departure times. As the coverage is increased the system enters a diffusive regime resulting from the interplay of particle desorption and diffusion. This interplay leads to much longer bound state lifetimes, a phenomenon qualitatively similar to aging in glassy systems. The diffusion behavior is analogous to dispersive transport in disordered semiconductors: depending on the interaction parameters it may range from a finite renormalization of the diffusion coefficient to anomalous, subdiffusive behavior. We make connections to recent experiments and discuss the implications for future studies.Comment: v2: substantially revised version, new treatment of localized regime, 19 pages, 10 figure

Kinetic limitations of cooperativity based drug delivery systems

We study theoretically a novel drug delivery system that utilizes the overexpression of certain proteins in cancerous cells for cell specific chemotherapy. The system consists of dendrimers conjugated with "keys" (ex: folic acid) which "key-lock" bind to particular cell membrane proteins (ex: folate receptor). The increased concentration of "locks" on the surface leads to a longer residence time for the dendrimer and greater incorporation into the cell. Cooperative binding of the nanocomplexes leads to an enhancement of cell specificity. However, both our theory and detailed analysis of in-vitro experiments indicate that the degree of cooperativity is kinetically limited. We demonstrate that cooperativity and hence the specificity to particular cell type can be increased by making the strength of individual bonds weaker, and suggest a particular implementation of this idea. The implications of the work for optimizing the design of drug delivery vehicles are discussed.Comment: 4 pages, 4 figures, v3: minor revision

Energy losses of fast heavy-ion projectiles in dense hydrogen plasmas

It has been recently shown that the Bethe-Larkin formula for the energy losses of fast heavy-ion projectiles in dense hydrogen plasmas is corrected by the electron-ion correlations [Phys. Rev. Lett. \textbf{101}, 075002 (2008)]. We report numerical estimates of this correction based on the values of $g_{ei}(0)$ obtained by numerical simulations in [Phys. Rev. E \textbf{61}, 3470 (2000)]. We also extend this result to the case of projectiles with dicluster charge distribution. We show that the experimental visibility of the electron-ion correlation correction is enhanced in the case of dicluster projectiles with randomly orientated charge centers. Although we consider here the hydrogen plasmas to make the effect physically more clear, the generalization to multispecies plasmas is straightforward.Comment: 5 pages, 1 figure. International Conference on Strongly Coupled Coulomb Systems 2008, Camerino (Italy). To appear in J. Phys.

Subject self-determination of the philosophy of evil

В статье дается набросок философии зла, исследующей силы, воздействующей на морального субъекта. Автор дает определение зла как силы, лишенной принципа ее применения.The article gives an outline of the philosophy of evil, which studies forced exerted on the moral subject. The author gives the definition of evil as force without principle of its application

Coulomb Charging Effects in an Open Quantum Dot

Low-temperature transport properties of a lateral quantum dot formed by overlaying finger gates in a clean one-dimensional channel are investigated. Continuous and periodic oscillations superimposed upon ballistic conductance steps are observed, when the conductance G of the dot changes within a wide range 0<G<6e^2/h. Calculations of the electrostatics confirm that the measured periodic conductance oscillations correspond to successive change of the total charge of the dot by $e$. By modelling the transport it is shown that the progression of the Coulomb oscillations into the region G>2e^2/h may be due to suppression of inter-1D-subband scattering. Fully transmitted subbands contribute to coherent background of conductance, while sequential tunneling via weakly transmitted subbands leads to Coulomb charging of the dot.Comment: 12 pages, RevTeX, 15 eps figures included, submitted to Phys. Rev.