Indicators of dental health in young adults

To assess the level of dental health of key WHO groups, as well as the intensity and prevalence of caries and non-carious lesions, 660 young people were examined according to the procedure recommended by WHO in the Russian Federation. Epidemiology of the main dental diseases in Ufa is characterized by a significant spread of caries to 98 ± 0,001%, while the intensity of the carious process averaged 12.29 ± 0.97, the prevalence of non-carious lesions was 60%.Для оценки уровня стоматологического здоровья ключевых групп по ВОЗ, а также интенсивности и распространенности кариеса и некариозных поражений проведено обследование 660 лиц молодого возраста по методике, рекомендованной ВОЗ в РФ. Эпидемиология основных стоматологических заболеваний в Уфе характеризуется значительным распространением кариеса до 98±0,001%, при этом интенсивность кариозного процесса составила в среднем 12,29±0,97, распространенность некариозных поражений составила 60%

STUDY OF CARDIOPROTECTIVE AND ANTI-ISCHEMIC EFFECTIVENESS OF STANDARD TREATMENT FOR ISCHEMIC HEART DISEASE WITH ADDITION OF PERINDOPRIL ARGININE, IN OLDER PATIENTS

Aim. To evaluate the cardioprotective, anti-ischemic and vasoprotective effectiveness of perindopril arginine (Prestarium А®, Les Laboratories Servier, France) in stable angina patients of older age, after myocardial infarction (MI).Material and methods. Totally, 68 patients of older age (72±12 y.) included, with stable angina, who had MI. All patients underwent echocardiography with dopplerographic analysis of transmitral blood flow, Holter monitoring of ECG, ultrasound dopplerography of carotid arteries. Patients from the 1 group (33 persons) were taking standard therapy of stable angina. Patients from the 2 group (n=35) as addition were taking PA 10 mg daily.Results. By the data of Holter ECG, in patients of both groups there was decrease of mean frequency of angina attacks (by 76,4% in 1 group, by 86,3% in 2), need for nitroglycerin use (by 68,7% and 71,3%, resp.), frequency of ischemia episodes (by 35,5% and 55,6%, resp.), total daily duration of ischemia (50,3% and 49,7%), depth of ischemic ST segment depression (44,6% and 58,6%, resp.). There was more prominent significant decrease of the parameters mentioned, in patients taking Prestarium А®. Also, in the 2 group patients the decrease of intima-media thickness of the right and left common carotid arteries was more significant than in the 1 group. In 2 group there was increase of relation of the peak velocities of the left ventricle (LV) filling in early phase of diastole and in atrium systole phase, by 14,6% and decrease of end-diastolic size of the LV by 10,9%.Conclusion. Usage of Prestarium А® in stable angina patients of older age, after MI, was effective, which presented with the decrease of the frequency and intensity of angina attacks, slowing of desadaptive LV remodeling processes, improvement of clinical condition, decrease of supraventricular rhythm disorders, positive influence on the heart and vessels, hence having vasoprotective and cardioprotective effect

The main regularities of the ratio between riverbed and basin components of erosion and suspended sediment yield in river basins of the USA

© 2019 Russian Academy of Sciences. All rights reserved. Suspended sediment yield is one of the objective and sufficiently accurate measures of erosion intensity in river basinsriver basins. In first approximation, it can be divided into the riverbed component-r(rb), the products of vertical and horizontal riverbed deformations), and basin component-r(bas), the products of soil and gully erosion. An attempt was made to distinguish this erosion structure in the USA river basins based on the partition of suspended sediments of 224 rivers (based on the data from the US Geological Service on the average monthly water discharges and suspended sediment yields) according to the method proposed by one of the authors of the paper, as well as an assessment of its factor dependence. The average r(rb) value for the analyzed rivers of the USA is 7.9±1.1%: For lowland rivers-10.6±1.7%, for low-mountain (including high uplands) rivers-5.7±1.5%, for mid-mountain rivers-4.3±1.5%. The geomorphic factor, landscape and climatic conditions within the river basins have a major impact on the suspended sediments flux ratio/(ib)/r(bas). Thus, in the USA plains, the largest average r(rb) portion is in the forest landscapes (taiga, mixed and broadleaf forests of the temperate zone, subtropical forests)-10-15%. On the contrary, in the arid landscapes (semi-deserts) this value does not exceed 1%. Within these general trends, there are quite strong variations in the/)/r(bas)-estimates and their factor dependence on the US rivers with the rivers of Northern Eurasia (the territory of the former Soviet Union) makes it possible to reveal good convergence of the results obtained in these parts of the Earth, and to suggest the universal nature of the revealed regularities (in total for 684 river basins) for the whole temperate (partly for subtropical and tropical) zone of the Northern hemisphere of our planet

The main regularities of the ratio between riverbed and basin components of erosion and suspended sediment yield in river basins of the USA

© 2019 Russian Academy of Sciences. All rights reserved. Suspended sediment yield is one of the objective and sufficiently accurate measures of erosion intensity in river basinsriver basins. In first approximation, it can be divided into the riverbed component-r(rb), the products of vertical and horizontal riverbed deformations), and basin component-r(bas), the products of soil and gully erosion. An attempt was made to distinguish this erosion structure in the USA river basins based on the partition of suspended sediments of 224 rivers (based on the data from the US Geological Service on the average monthly water discharges and suspended sediment yields) according to the method proposed by one of the authors of the paper, as well as an assessment of its factor dependence. The average r(rb) value for the analyzed rivers of the USA is 7.9±1.1%: For lowland rivers-10.6±1.7%, for low-mountain (including high uplands) rivers-5.7±1.5%, for mid-mountain rivers-4.3±1.5%. The geomorphic factor, landscape and climatic conditions within the river basins have a major impact on the suspended sediments flux ratio/(ib)/r(bas). Thus, in the USA plains, the largest average r(rb) portion is in the forest landscapes (taiga, mixed and broadleaf forests of the temperate zone, subtropical forests)-10-15%. On the contrary, in the arid landscapes (semi-deserts) this value does not exceed 1%. Within these general trends, there are quite strong variations in the/)/r(bas)-estimates and their factor dependence on the US rivers with the rivers of Northern Eurasia (the territory of the former Soviet Union) makes it possible to reveal good convergence of the results obtained in these parts of the Earth, and to suggest the universal nature of the revealed regularities (in total for 684 river basins) for the whole temperate (partly for subtropical and tropical) zone of the Northern hemisphere of our planet

Application of the MODIS “snow cover” product for identification of the snow cover pattern in Gis-Baikal region

Validation of remote sensing data MODIS «snow cover» in the period from September to May 2000/01, 2007/08, 2008/09 is realized on the base of weather stations data. Good repeatability of weather stations data and snow cover data is shown (more than 80% when snow depth is exceeds 2 cm). The minimum accuracy is in May and October for the variety of snowfall winters. Remote sensing data give possibility to extend the dot information of hydrometeorological stations network on the spatial snow distribution to the mountainous area of Predbajkalje where ground-based observations are absent. According to remote sensing earlier appearance and later melting of snow in mountain areas were identified. The plains and basins areas are characterized by later appearance and earlier melting of snow

The usage of unremovable artefacts for the quantitative “reading” of nanonoises in voltammetry

© The Royal Society of Chemistry and the Centre National de la Recherche Scientifique. We propose two modified and rather “universal” methods for the quantitative evaluation of electrochemical noises registered in running voltammetric sensor systems in the presence of unremovable artefacts. One approach is based on the discrete geometrical invariant (DGI) method and another is based on the usage of modified Fourier transform. Both approaches did not use model suppositions and were free from the treatment errors. We discussed the reasons for the appearance of the artefacts and showed their applications for increasing the sensitivity and specificity in the detection of some complex organic fluids. As an example, we obtained olive oils from two different producers for their definite differentiation. The selected olive oils from two different countries (Italy and Spain) were placed in working tube electrode cells, and we realized the possibility for the extraction of some useful information from the large amount of nanocurrents. The obtained quantitative parameters allowed the differentiation of URA from possible random noises. These two treatment methods have been proven to be rather “universal” and can be used for the analysis of other URAs having different natures

Detection of additives with the help of discrete geometrical invariants

© 2019 by the authors. In this paper, we propose a general mathematical method for the detection of electrochemical additives in a given solute with the help of discrete geometrical invariants (DGI). This idea is based on the generalization of Pythagor's theorem that can be proved for two random sets located in the two-dimensional (2D) plane. This statement follows from the previous ideas proposed by Babenko, who essentially modernized the well-known theorem and propagated it on a wide class of "right" discrete sets with different symmetry. However, attentive analysis of these results shows that there is a possibility for their further generalization. For practical purposes, it is important to have discrete and deterministic curve(s) with the limited number of parameters that enables comparing two random sets of any nature if their quantitative description expressed in terms of the "best-fit" model is absent. Under the best-fit model, we imply the microscopic model that enables describing the measured data in terms of the minimal set of the fitting parameters. We propose at least two invariants: (a) the curve of the second order that coincides with the classical ellipse oriented at an arbitrary direction relative to the X- and Y-axes, and (b) the curve of the fourth order that has eight quantitative parameters and includes the cross-combination of the integer moments. In this paper, the DGIs of both types were used. These curves are made useful for the solution of a key problem in electrochemistry, i.e.; the detection of small concentrations of D-tryptophan (6.54 ÷ 38.7) 10 -5 mol L -1 in a given solute (phosphate buffer solution (Na 2 HPO 4 + KH 2 PO 4 ) with pH = 6.86) that was activated by electrodes of two types-Pt (platinum) and C (carbon). The DGI method is free from treatment errors and model suppositions; therefore, it can be applied for the detection of small additives in a given solute and a further description can be attained with the help of a monotone/calibration curve expressed by means of parameters associated with the DGI

Detection of additives with the help of discrete geometrical invariants

© 2019 by the authors. In this paper, we propose a general mathematical method for the detection of electrochemical additives in a given solute with the help of discrete geometrical invariants (DGI). This idea is based on the generalization of Pythagor's theorem that can be proved for two random sets located in the two-dimensional (2D) plane. This statement follows from the previous ideas proposed by Babenko, who essentially modernized the well-known theorem and propagated it on a wide class of "right" discrete sets with different symmetry. However, attentive analysis of these results shows that there is a possibility for their further generalization. For practical purposes, it is important to have discrete and deterministic curve(s) with the limited number of parameters that enables comparing two random sets of any nature if their quantitative description expressed in terms of the "best-fit" model is absent. Under the best-fit model, we imply the microscopic model that enables describing the measured data in terms of the minimal set of the fitting parameters. We propose at least two invariants: (a) the curve of the second order that coincides with the classical ellipse oriented at an arbitrary direction relative to the X- and Y-axes, and (b) the curve of the fourth order that has eight quantitative parameters and includes the cross-combination of the integer moments. In this paper, the DGIs of both types were used. These curves are made useful for the solution of a key problem in electrochemistry, i.e.; the detection of small concentrations of D-tryptophan (6.54 ÷ 38.7) 10 -5 mol L -1 in a given solute (phosphate buffer solution (Na 2 HPO 4 + KH 2 PO 4 ) with pH = 6.86) that was activated by electrodes of two types-Pt (platinum) and C (carbon). The DGI method is free from treatment errors and model suppositions; therefore, it can be applied for the detection of small additives in a given solute and a further description can be attained with the help of a monotone/calibration curve expressed by means of parameters associated with the DGI

Prospects of Chemotherapy for Gastrointestential Stromal Colon Tumours

Gastrointetinal stromal tumours are the most common primary mesenchymal tumours of the gastrointestinal tract. According to statistical data, the annual incidence of this pathology in Russia comprises 13 patients per 1 million inhabitants, i.e. about 2,000 patients per year on average. In the United States, 3,000–4,000 cases are registered every year. This article discusses general and specific issues associated with morbidity and mortality from gastrointestinal stromal tumours, as well as reasons for the low efficacy of surgical and targeted therapies. Methods for combined treatment of patients with gastrointestinal stromal tumours are proposed. The treatment of such pathologies has evolved with the development of immunohystochemical analytical procedures and therapies against KIT/PDGFRA-specific protooncogenes, as well as the emergence of low-molecular kinase inhibitors. However, the probability of non-recurrence survival can only be increased by complete surgical removal of gastrointestinal stromal colon tumours. In the surgical treatment, three main approaches are defined: the initial stage of treatment, provided that the tumour is resectable and has a small size; surgical treatment after neoadjuvant therapy; symptomatic treatment, so-called ‘debulking surgery’. Adjuvant targeted therapy with Imatinib provides for a high objective response. The use of Imatinib chemotherapy determines the efficacy and radicality of surgical treatment in most cases. In general, the question of treating gastrointestinal stromal colon tumours is still relevant, requiring further research and objective evaluation of all technical and tactical approaches in the context of distant results

The usage of unremovable artefacts for the quantitative “reading” of nanonoises in voltammetry

© The Royal Society of Chemistry and the Centre National de la Recherche Scientifique. We propose two modified and rather “universal” methods for the quantitative evaluation of electrochemical noises registered in running voltammetric sensor systems in the presence of unremovable artefacts. One approach is based on the discrete geometrical invariant (DGI) method and another is based on the usage of modified Fourier transform. Both approaches did not use model suppositions and were free from the treatment errors. We discussed the reasons for the appearance of the artefacts and showed their applications for increasing the sensitivity and specificity in the detection of some complex organic fluids. As an example, we obtained olive oils from two different producers for their definite differentiation. The selected olive oils from two different countries (Italy and Spain) were placed in working tube electrode cells, and we realized the possibility for the extraction of some useful information from the large amount of nanocurrents. The obtained quantitative parameters allowed the differentiation of URA from possible random noises. These two treatment methods have been proven to be rather “universal” and can be used for the analysis of other URAs having different natures