Properties of Foreshocks and Aftershocks of the Non-Conservative SOC Olami-Feder-Christensen Model: Triggered or Critical Earthquakes?

Following Hergarten and Neugebauer [2002] who discovered aftershock and foreshock sequences in the Olami-Feder-Christensen (OFC) discrete block-spring earthquake model, we investigate to what degree the simple toppling mechanism of this model is sufficient to account for the properties of earthquake clustering in time and space. Our main finding is that synthetic catalogs generated by the OFC model share practically all properties of real seismicity at a qualitative level, with however significant quantitative differences. We find that OFC catalogs can be in large part described by the concept of triggered seismicity but the properties of foreshocks depend on the mainshock magnitude, in qualitative agreement with the critical earthquake model and in disagreement with simple models of triggered seismicity such as the Epidemic Type Aftershock Sequence (ETAS) model [Ogata, 1988]. Many other features of OFC catalogs can be reproduced with the ETAS model with a weaker clustering than real seismicity, i.e. for a very small average number of triggered earthquakes of first generation per mother-earthquake.Comment: revtex, 19 pages, 8 eps figure

Intestinal Acid Sphingomyelinase Protects From Severe Pathogen-Driven Colitis

Inflammatory diseases of the gastrointestinal tract are emerging as a global problem with increased evidence and prevalence in numerous countries. A dysregulated sphingolipid metabolism occurs in patients with ulcerative colitis and is discussed to contribute to its pathogenesis. In the present study, we determined the impact of acid sphingomyelinase (Asm), which catalyzes the hydrolysis of sphingomyelin to ceramide, on the course of Citrobacter (C.) rodentium-driven colitis. C. rodentium is an enteric pathogen and induces colonic inflammation very similar to the pathology in patients with ulcerative colitis. We found that mice with Asm deficiency or Asm inhibition were strongly susceptible to C. rodentium infection. These mice showed increased levels of C. rodentium in the feces and were prone to bacterial spreading to the systemic organs. In addition, mice lacking Asm activity showed an uncontrolled inflammatory Th1 and Th17 response, which was accompanied by a stronger colonic pathology compared to infected wild type mice. These findings identified Asm as an essential regulator of mucosal immunity to the enteric pathogen C. rodentium

Solar and Atmospheric Neutrinos: Background Sources for the Direct Dark Matter Searches

In experiments for direct dark matter searches, neutrinos coherently scattering off nuclei can produce similar events as Weakly Interacting Massive Particles (WIMPs). The calculated count rate for solar neutrinos in such experiments is a few events per ton-year. This count rate strongly depends on the nuclear recoil energy threshold achieved in the experiments for the WIMP search. We show that solar neutrinos can be a serious background source for direct dark matter search experiments using Ge, Ar, Xe and CaWO_4 as target materials. To reach sensitivities better than approximatly 10^-10 pb for the elastic WIMP nucleon spin-independent cross section in the zero-background limit, energy thresholds for nuclear recoils should be approximatly >2.05 keV for CaWO_4, >4.91 keV for Ge, >2.89 keV for Xe, and >8.62 keV for Ar as target material. Next-generation experiments should not only strive for a reduction of the present energy thresholds but mainly focus on an increase of the target mass. Atmospheric neutrinos limit the achievable sensitivity for the background-free direct dark matter search to approximatly >10^-12 pb.Comment: accepted by Astroparticle Physic