12 research outputs found
Effect of the DGAT1 inhibitor pradigastat on triglyceride and apoB48 levels in patients with familial chylomicronemia syndrome
Ī³-Hydroxy-1,N2-propano-2ā²-deoxyguanosine DNA Adduct Conjugates the N-Terminal Amine of the KWKK Peptide via a Carbinolamine Linkage
SurfaceāEnhanced Polymerization via Schiff-Base Coupling at the SolidāWater Interface under pH Control
On-surface polymerization realized at the solidāliquid interface represents a promising route to obtain stable and conductive organic layers with tunable properties. We present here spectroscopic evidence of Ļ-conjugated polymer formation at the interface between an iodine-modified Au(111) and an aqueous solution. Schiff-base coupling has been used to drive the reaction by changing the pH. Scanning tunneling microscopy (STM) investigations show that the substrate acts as a template driving the formation of 1D ordered nanostructures. All the chemical states of the molecules on the surface have been identified and their evolution as a function of the pH has been monitored by synchrotron radiation X-ray photoelectron spectroscopy (XPS), demonstrating that two polymeric phases, undistinguishable by STM, exist on the surface: intermediate state and Ļ-conjugated final product. The I/Au(111) substrate enhances the formation of Ļ-conjugated polymers, as established comparing their production on the surface and in the bulk solution