Update on the Measurement of alpha_S with a 500 GeV Linear Collider

An update on the prospects for the precise measurement of the strong coupling constant alpha_S at a high energy Linear Collider via the three-jet rate is presented. In particular, the issue of the distribution of center-of-mass energies of the identified q-qbar event sample, which can affect the determination of \alpha_S at the scale Q^2=(500 GeV)^2$, is addressed.Comment: 4 pages, 3 figures, LaTex, requires epsfig and aipproc macro

The Fishes of Maryland

Fish, from both a commercial and a sporting standpoint. Based on fishes collected in Maryland only. A general treatise on fishes, setting forth the species, describing them and telling of their distribution, habits and other pertinent facts such as adaptations and coloring. Includes marine, freshwater littoral fishes. (PDF contains 120 pages

The Chemical Composition of {\tau} Ceti and Possible Effects on Terrestrial Planets

{\tau} Ceti (HD10700), a G8 dwarf with solar mass of 0.78, is a close (3.65 pc) sun-like star where 5 possibly terrestrial planet candidates (minimum masses of 2, 3.1, 3.5, 4.3, and 6.7 Earth masses) have recently been discovered. We report abundances of 23 elements using spectra from the MIKE spectrograph on Magellan. Using stellar models with the abundances determined here, we calculate the position of the classical habitable zone with time. At the current best fit age, 7.63 Gy, up to two planets (e and f) may be in the habitable zone, depending on atmospheric properties. The Mg/Si ratio of the star is found to be 1.78, which is much greater than for Earth (about 1.2). With a system that has such an excess of Mg to Si ratio it is possible that the mineralogical make-up of planets around {\tau} Ceti could be significantly different from that of Earth, with possible oversaturation of MgO, resulting in an increase in the content of olivine and ferropericlase compared with Earth. The increase in MgO would have a drastic impact on the rheology of the mantles of the planets around {\tau} Ceti.Comment: 17 pages, 1 figure, supplemental table, Astrophysical Journa

Positively Correlated miRNA-miRNA Regulatory Networks in Mouse Frontal Cortex During Early Stages of Alcohol Dependence

Although the study of gene regulation via the action of specific microRNAs (miRNAs) has experienced a boom in recent years, the analysis of genome-wide interaction networks among miRNAs and respective targeted mRNAs has lagged behind. MicroRNAs simultaneously target many transcripts and fine-tune the expression of genes through cooperative/combinatorial targeting. Therefore, they have a large regulatory potential that could widely impact development and progression of diseases, as well as contribute unpredicted collateral effects due to their natural, pathophysiological, or treatment-induced modulation. We support the viewpoint that whole mirnome-transcriptome interaction analysis is required to better understand the mechanisms and potential consequences of miRNA regulation and/or deregulation in relevant biological models. In this study, we tested the hypotheses that ethanol consumption induces changes in miRNA-mRNA interaction networks in the mouse frontal cortex and that some of the changes observed in the mouse are equivalent to changes in similar brain regions from human alcoholics. Results: miRNA-mRNA interaction networks responding to ethanol insult were identified by differential expression analysis and weighted gene coexpression network analysis (WGCNA). Important pathways (coexpressed modular networks detected by WGCNA) and hub genes central to the neuronal response to ethanol are highlighted, as well as key miRNAs that regulate these processes and therefore represent potential therapeutic targets for treating alcohol addiction. Importantly, we discovered a conserved signature of changing miRNAs between ethanol-treated mice and human alcoholics, which provides a valuable tool for future biomarker/diagnostic studies in humans. We report positively correlated miRNA-mRNA expression networks that suggest an adaptive, targeted miRNA response due to binge ethanol drinking. Conclusions: This study provides new evidence for the role of miRNA regulation in brain homeostasis and sheds new light on current understanding of the development of alcohol dependence. To our knowledge this is the first report that activated expression of miRNAs correlates with activated expression of mRNAs rather than with mRNA downregulation in an in vivo model. We speculate that early activation of miRNAs designed to limit the effects of alcohol-induced genes may be an essential adaptive response during disease progression.NIAAA 5R01AA012404, 5P20AA017838, 5U01AA013520, P01AA020683, 5T32AA007471-24/25Waggoner Center for Alcohol and Addiction Researc

Electrical spin injection from an organic-based ferrimagnet in a hybrid organic/inorganic heterostructure

We report the successful extraction of spin polarized current from the organic-based room temperature ferrimagnetic semiconductor V[TCNE]x (x~2, TCNE: tetracyanoethylene; TC ~ 400 K, EG ~ 0.5 eV, s ~ 10-2 S/cm) and its subsequent injection into a GaAs/AlGaAs light-emitting diode (LED). The spin current tracks the magnetization of V[TCNE]x~2, is weakly temperature dependent, and exhibits heavy hole / light hole asymmetry. This result has implications for room temperature spintronics and the use of inorganic materials to probe spin physics in organic and molecular systems

Dissipation in nanocrystalline-diamond nanomechanical resonators

We have measured the dissipation and frequency of nanocrystalline-diamond nanomechanical resonators with resonant frequencies between 13.7 MHz and 157.3 MHz, over a temperature range of 1.4–274 K. Using both magnetomotive network analysis and a time-domain ring-down technique, we have found the dissipation in this material to have a temperature dependence roughly following T^(0.2), with Q^(–1) ≈ 10^(–4) at low temperatures. The frequency dependence of a large dissipation feature at ~35–55 K is consistent with thermal activation over a 0.02 eV barrier with an attempt frequency of 10 GHz

Very Shallow Water Bathymetry Retrieval from Hyperspectral Imagery at the Virginia Coast Reserve (VCR\u2707) Multi-Sensor Campaign

A number of institutions, including the Naval Research Laboratory (NRL), have developed look up tables for remote retrieval of bathymetry and in-water optical properties from hyperspectral imagery (HSI) [6]. For bathymetry retrieval, the lower limit is the very shallow water case (here defined as \u3c 2m), a depth zone which is not well resolved by many existing bathymetric LIDAR sensors, such as SHOALS [4]. The ability to rapidly model these shallow water depths from HSI directly has potential benefits for combined HSI/LIDAR systems such as the Compact Hydrographic Airborne Rapid Total Survey (CHARTS) [10]. In this study, we focused on the validation of a near infra-red feature, corresponding to a local minimum in absorption (and therefore a local peak in reflectance), which can be correlated directly to bathymetry with a high degree of confidence. Compared to other VNIR wavelengths, this particular near-IR feature corresponds to a peak in the correlation with depth in this very shallow water regime, and this is a spectral range where reflectance depends primarily on water depth (water absorption) and bottom type, with suspended constituents playing a secondary role

Controllable valley splitting in silicon quantum devices

Silicon has many attractive properties for quantum computing, and the quantum dot architecture is appealing because of its controllability and scalability. However, the multiple valleys in the silicon conduction band are potentially a serious source of decoherence for spin-based quantum dot qubits. Only when these valleys are split by a large energy does one obtain well-defined and long-lived spin states appropriate for quantum computing. Here we show that the small valley splittings observed in previous experiments on Si/SiGe heterostructures result from atomic steps at the quantum well interface. Lateral confinement in a quantum point contact limits the electron wavefunctions to several steps, and enhances the valley splitting substantially, up to 1.5 meV. The combination of electronic and magnetic confinement produces a valley splitting larger than the spin splitting, which is controllable over a wide range. These results improve the outlook for realizing spin qubits with long coherence times in silicon-based devices.Comment: Published version, including supplementary material