Magellan

The Magellan Mission consists of a single spacecraft to be placed in an elliptical orbit around Venus. The main objective of the mission is to perform radar imaging, altimetry, and reflectivity of 90 percent of the planet for one Venusian year (243 days). A flight profile is given, and information is presented in tabular form on the following topics: Deep Space Network support, frequency assignments, telemetry, command, and tracking support responsibilities

A high-rate telemetry system for the Mariner Mars 1969 mission

High rate telemetry system for Mariner Mars 1969 missio

Study of controlled diffusion stator blading. 1. Aerodynamic and mechanical design report

Pratt & Whitney Aircraft is conducting a test program for NASA in order to demonstrate that a controlled-diffusion stator provides low losses at high loadings and Mach numbers. The technology has shown great promise in wind tunnel tests. Details of the design of the controlled diffusion stator vanes and the multiple-circular-arc rotor blades are presented. The stage, including stator and rotor, was designed to be suitable for the first-stage of an advanced multistage, high-pressure compressor

Oxygen-related traps in pentacene thin films: Energetic position and implications for transistor performance

We studied the influence of oxygen on the electronic trap states in a pentacene thin film. This was done by carrying out gated four-terminal measurements on thin-film transistors as a function of temperature and without ever exposing the samples to ambient air. Photooxidation of pentacene is shown to lead to a peak of trap states centered at 0.28 eV from the mobility edge, with trap densities of the order of 10(18) cm(-3). These trap states need to be occupied at first and cause a reduction in the number of free carriers, i.e. a consistent shift of the density of free holes as a function of gate voltage. Moreover, the exposure to oxygen reduces the mobility of the charge carriers above the mobility edge. We correlate the change of these transport parameters with the change of the essential device parameters, i.e. subthreshold performance and effective field-effect mobility. This study supports the assumption of a mobility edge for charge transport, and contributes to a detailed understanding of an important degradation mechanism of organic field-effect transistors. Deep traps in an organic field-effect transistor reduce the effective field-effect mobility by reducing the number of free carriers and their mobility above the mobility edge.Comment: 13 pages, 14 figures, to be published in Phys. Rev.

Analysis of systems hardware flown on LDEF. Results of the systems special investigation group

The Long Duration Exposure Facility (LDEF) was retrieved after spending 69 months in low Earth orbit (LEO). LDEF carried a remarkable variety of mechanical, electrical, thermal, and optical systems, subsystems, and components. The Systems Special Investigation Group (Systems SIG) was formed to investigate the effects of the long duration exposure to LEO on systems related hardware and to coordinate and collate all systems analysis of LDEF hardware. Discussed here is the status of the LDEF Systems SIG investigation through the end of 1991

Learning to serve together : creating an inter-continental classroom for service-learning

Version of RecordPublishe

Pharmacological Inhibition of CDK8 in Triple-Negative Breast Cancer Cell line MDA-MB-468 Increases E2F1 Protein, Induces Phosphorylation of STAT3 and Apoptosis

Cyclin-dependent kinase 8 (CDK8) has been identified as a colon cancer oncogene. Since this initial observation, CDK8 has been implicated as a potential driver of other cancers including acute myelogenous leukemia (AML) and some breast cancers. Here, we observed different biological responses to CDK8 inhibition among colon cancer cell lines and the triple-negative breast cancer (TNBC) cell line MDA-MB-468. When treated with CDK8 inhibitor 4, all treated cell lines responded with decreased cell viability and increased apoptosis. In the MDA-MB-468 cell line, the decrease in cell viability was dependent on increased phosphorylation of signal transducer and activator of transcription 3 (STAT3), which is not observed in the colon cancer cell lines. Furthermore, increased STAT3 phosphorylation in 4 treated MDA-MB-468 cells was dependent on increased transcription factor E2F1 protein. These results are consistent with previous reports of exogenous expression of E2F1-induced apoptosis in MDA-MB-468 cells

Adolescent binge-like alcohol alters sensitivity to acute alcohol effects on dopamine release in the nucleus accumbens of adult rats

Early onset of alcohol drinking has been associated with alcohol abuse in adulthood. The neurobiology of this phenomenon is unclear, but mesolimbic dopamine pathways, which are dynamic during adolescence, may play a role

Modeling and Simulation Techniques Used in High Strain Rate Projectile Impact

A series of computational models and simulations were conducted for determining the dynamic responses of a solid metal projectile impacting a target under a prescribed high strain rate loading scenario in three-dimensional space. The focus of this study was placed on two different modeling techniques within finite element analysis available in the Abaqus software suite. The first analysis technique relied heavily on more traditional Lagrangian analysis methods utilizing a fixed mesh, while still taking advantage of the finite difference integration present under the explicit analysis approach. A symmetry reduced model using the Lagrangian coordinate system was also developed for comparison in physical and computational performance. The second analysis technique relied on a mixed model that still made use of some Lagrangian modeling, but included smoothed particle hydrodynamics techniques as well, which are mesh free. The inclusion of the smoothed particle hydrodynamics was intended to address some of the known issues in Lagrangian analysis under high displacement and deformation. A comparison of the models was first performed against experimental results as a validation of the models, then the models were compared against each other based on closeness to experimentation and computational performance