5 research outputs found

    Selective Breeding for a Behavioral Trait Changes Digit Ratio

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    The ratio of the length of the second digit (index finger) divided by the fourth digit (ring finger) tends to be lower in men than in women. This 2D∶4D digit ratio is often used as a proxy for prenatal androgen exposure in studies of human health and behavior. For example, 2D∶4D ratio is lower (i.e. more “masculinized”) in both men and women of greater physical fitness and/or sporting ability. Lab mice have also shown variation in 2D∶4D as a function of uterine environment, and mouse digit ratios seem also to correlate with behavioral traits, including daily activity levels. Selective breeding for increased rates of voluntary exercise (wheel running) in four lines of mice has caused correlated increases in aerobic exercise capacity, circulating corticosterone level, and predatory aggression. Here, we show that this selection regime has also increased 2D∶4D. This apparent “feminization” in mice is opposite to the relationship seen between 2D∶4D and physical fitness in human beings. The present results are difficult to reconcile with the notion that 2D∶4D is an effective proxy for prenatal androgen exposure; instead, it may more accurately reflect effects of glucocorticoids, or other factors that regulate any of many genes

    Reversibility of minimal hepatic encephalopathy following liver transplantation in Egyptian cirrhotic patients

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    CompilaciĂłn de resĂșmenes de los trabajos presentados en el I Encuentro de Sanidad Forestal de la Facultad de Ciencias Agrarias y Forestales (UNLP), realizado el 14 de noviembre de 2013 y organizado por el Curso de ProtecciĂłn Forestal de la Facultad de Ciencias Agrarias y Forestales (UNLP).Facultad de Ciencias Agrarias y Forestale

    Inflammatory signaling mechanisms in bipolar disorder

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