71 research outputs found

    Transmission through correlated Cun_nCoCun_n heterostructures

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    The effects of local electronic interactions and finite temperatures upon the transmission across the Cu4_4CoCu4_4 metallic heterostructure are studied in a combined density functional and dynamical mean field theory. It is shown that, as the electronic correlations are taken into account via a local but dynamic self-energy, the total transmission at the Fermi level gets reduced (predominantly in the minority spin channel), whereby the spin polarization of the transmission increases. The latter is due to a more significant dd-electrons contribution, as compared to the non-correlated case in which the transport is dominated by ss and pp electrons.Comment: 29 pages, 7 figures, submited to PR

    Emergence of classical behavior from the quantum spin

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    Classical Hamiltonian system of a point moving on a sphere of fixed radius is shown to emerge from the constrained evolution of quantum spin. The constrained quantum evolution corresponds to an appropriate coarse-graining of the quantum states into equivalence classes, and forces the equivalence classes to evolve as single units representing the classical states. The coarse-grained quantum spin with the constrained evolution in the limit of the large spin becomes indistinguishable from the classical system

    Emergency treatment in case of cyanide poisoning during fumigation

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    Ovaj rad se bavi osnovnim aspektima toksikologije i klinike trovanja cijanidima, organizacije i metodologije pružanja prve pomoći kod trovanja cijanovodonikom prilikom vršenja furnigacija. Osim toga, dat je i komparativni prikaz najvažnijih antidota cijanida.The paper deals with the principal aspects of the toxicology and clinical treatment of cyanide poisoning and with the organisation of emergency medical care in cases of cyanide poisoning during fumigation. Comparative characteristics of the most important cyanide antidotes are also presented

    Diversity of Cortical Interneurons in Primates: The Role of the Dorsal Proliferative Niche

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    Summary Evolutionary elaboration of tissues starts with changes in the genome and location of the stem cells. For example, GABAergic interneurons of the mammalian neocortex are generated in the ventral telencephalon and migrate tangentially to the neocortex, in contrast to the projection neurons originating in the ventricular/subventricular zone (VZ/SVZ) of the dorsal telencephalon. In human and nonhuman primates, evidence suggests that an additional subset of neocortical GABAergic interneurons is generated in the cortical VZ and a proliferative niche, the outer SVZ. The origin, magnitude, and significance of this species-specific difference are not known. We use a battery of assays applicable to the human, monkey, and mouse organotypic cultures and supravital tissue to identify neuronal progenitors in the cortical VZ/SVZ niche that produce a subset of GABAergic interneurons. Our findings suggest that these progenitors constitute an evolutionary novelty contributing to the elaboration of higher cognitive functions in primates

    Association of acute Babesia canis infection and serum lipid, lipoprotein, and apoprotein concentrations in dogs

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    Background: Babesia canis infection induces a marked acute phase response (APR) that might be associated with alteration in lipid and lipoprotein metabolism and disease prognosis. Hypothesis: Dogs with B. canis-induced APR develop dyslipidemia with altered lipoprotein concentration and morphology. Animals: Twenty-nine client-owned dogs with acute B. canis infection and 10 clinically healthy control dogs. Methods: Observational cross-sectional study. Serum amyloid A (SAA) was measured using ELISA. Cholesterol, phospholipids, and triglycerides were determined biochemically. Lipoproteins were separated using agarose gel electrophoresis. Lipoprotein diameter was assessed by polyacrylamide gradient gel electrophoresis; correlation with ApoA-1 (radioimmunoassay) and SAA was determined. Results: Dogs with B. canis infection had a marked APR (median SAA, 168.3 μg/mL; range, 98.1-716.2 μg/mL) compared with controls (3.2 μg/mL, 2.0-4.2 μg/mL) (P lt .001). Dogs with B. canis infection had significantly lower median cholesterol (4.79 mmol/L, 1.89-7.64 mmol/L versus 6.15 mmol/L, 4.2-7.4 mmol/L) (P =.02), phospholipid (4.64 mmol/L, 2.6-6.6 mmol/L versus 5.72 mmol/L, 4.68-7.0 mmol/L) (P =.02), and α-lipoproteins (77.5%, 27.7%-93.5% versus 89.2%, 75.1%-93.5%) (P =.04), and higher ApoA-1 (1.36 U, 0.8-2.56 U versus 0.95 U, 0.73-1.54 U) concentrations (P =.02). Serum amyloid A correlated with high-density lipoproteins (HDLs) diameter (rho =.43; P =.03) and ApoA-1 (rho =.63, P lt .001). Conclusions and Clinical Importance: Major changes associated with B. canis-induced APR in dogs are related to concentration, composition, and morphology of HDL particles pointing to an altered reverse cholesterol transport. Parallel ApoA-1 and SAA concentration increase is a unique still unexplained pathophysiological finding
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